4LEV
Structure of human cGAS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cyclic GMP-AMP synthase | polymer | 369 | 43383.2 | 2 | UniProt (Q8N884) Pfam (PF03281) Pfam (PF20266) | Homo sapiens (human) | cGAMP synthase, cGAS, h-cGAS, Mab-21 domain-containing protein 1 |
| 2 | C, D (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 451 | Chemie (HOH) |
Sequence modifications
A, B: 157 - 522 (UniProt: Q8N884)
| PDB | External Database | Details |
|---|---|---|
| Phe 154 | - | expression tag |
| Glu 155 | - | expression tag |
| Leu 156 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86766.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 86897.2 |
