4LUQ
 
 | |
7BTN
 | |
5XMK
 | | Cryo-EM structure of the ATP-bound Vps4 mutant-E233Q complex with Vta1 (masked) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Vacuolar protein sorting-associated protein 4, Vacuolar protein sorting-associated protein VTA1 | | Authors: | Sun, S, Li, L, Yang, F, Wang, X, Fan, F, Li, X, Wang, H, Sui, S. | | Deposit date: | 2017-05-15 | | Release date: | 2017-08-09 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.18 Å) | | Cite: | Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution
Nat Commun, 8, 2017
|
|
3V6L
 | | Crystal Structure of caspase-6 inactivation mutation | | Descriptor: | Caspase-6 | | Authors: | Cao, Q, Wang, X.J, Liu, D.F, Li, L.F, Su, X.D. | | Deposit date: | 2011-12-20 | | Release date: | 2012-03-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Inhibitory mechanism of caspase-6 phosphorylation revealed by crystal structures, molecular dynamics simulations, and biochemical assays
J.Biol.Chem., 287, 2012
|
|
3V69
 | | Filia-N crystal structure | | Descriptor: | Protein Filia | | Authors: | Wang, J, Xu, M, Zhu, K, Li, L, Liu, X. | | Deposit date: | 2011-12-19 | | Release date: | 2012-02-15 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The N-terminus of FILIA Forms an Atypical KH Domain with a Unique Extension Involved in Interaction with RNA.
Plos One, 7, 2012
|
|
3MAZ
 | | Crystal Structure of the Human BRDG1/STAP-1 SH2 Domain in Complex with the NTAL pTyr136 Peptide | | Descriptor: | CheD family protein, MALONATE ION, Signal-transducing adaptor protein 1 | | Authors: | Kaneko, T, Huang, H, Zhao, B, Li, L, Liu, H, Voss, C.K, Wu, C, Schiller, M.R, Li, S.S. | | Deposit date: | 2010-03-24 | | Release date: | 2010-05-12 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Loops govern SH2 domain specificity by controlling access to binding pockets.
Sci.Signal., 3, 2010
|
|
7M2P
 | |
3HBF
 | | Structure of UGT78G1 complexed with myricetin and UDP | | Descriptor: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, Flavonoid 3-O-glucosyltransferase, URIDINE-5'-DIPHOSPHATE | | Authors: | Wang, X, Modolo, L, Li, L, Dixon, R. | | Deposit date: | 2009-05-04 | | Release date: | 2009-09-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures of glycosyltransferase UGT78G1 reveal the molecular basis for glycosylation and deglycosylation of (iso)flavonoids.
J.Mol.Biol., 392, 2009
|
|
3IS2
 | | 2.3 Angstrom Crystal Structure of a Cys71 Sulfenic Acid form of Vivid | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Vivid PAS protein VVD | | Authors: | Zoltowski, B.D, Lamb, J.S, Pabit, S.A, Li, L, Pollack, L, Crane, B.R. | | Deposit date: | 2009-08-25 | | Release date: | 2009-11-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Illuminating solution responses of a LOV domain protein with photocoupled small-angle X-ray scattering.
J.Mol.Biol., 393, 2009
|
|
6M3B
 | | hAPC-c25k23 Fab complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Vitamin K-dependent protein C heavy chain, Vitamin K-dependent protein C light chain, ... | | Authors: | Wang, X, Li, L, Zhao, X, Egner, U. | | Deposit date: | 2020-03-03 | | Release date: | 2020-07-08 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia.
Nat Commun, 11, 2020
|
|
5Z87
 | | Structural of a novel b-glucosidase EmGH1 at 2.3 angstrom from Erythrobacter marinus | | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BENZAMIDINE, ... | | Authors: | Li, J.X, Hu, X.J, Zhao, Y, Li, L. | | Deposit date: | 2018-01-31 | | Release date: | 2019-02-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and biochemical analysis of a novel b-glucosidase EmGH1 from Erythrobacter marinus
To Be Published
|
|
6CFF
 | | Stimulator of Interferon Genes Human | | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Stimulator of interferon genes protein | | Authors: | Fernandez, D, Li, L, Ergun, S.L. | | Deposit date: | 2018-02-14 | | Release date: | 2019-03-13 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.396 Å) | | Cite: | STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition.
Cell, 178, 2019
|
|
3OZJ
 | | Crystal structure of human retinoic X receptor alpha complexed with bigelovin and coactivator SRC-1 | | Descriptor: | (3aR,4S,4aR,7aR,8R,9aS)-4a,8-dimethyl-3-methylidene-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl acetate, Retinoic acid receptor RXR-alpha, SRC-1, ... | | Authors: | Zhang, H, Li, L, Chen, L, Hu, L, Shen, X. | | Deposit date: | 2010-09-25 | | Release date: | 2011-02-02 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure basis of bigelovin as a selective RXR agonist with a distinct binding mode
J.Mol.Biol., 407, 2011
|
|
3HBJ
 | | Structure of UGT78G1 complexed with UDP | | Descriptor: | Flavonoid 3-O-glucosyltransferase, URIDINE-5'-DIPHOSPHATE | | Authors: | Wang, X, Modolo, L, Li, L, Dixon, R. | | Deposit date: | 2009-05-04 | | Release date: | 2009-09-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures of glycosyltransferase UGT78G1 reveal the molecular basis for glycosylation and deglycosylation of (iso)flavonoids.
J.Mol.Biol., 392, 2009
|
|
6CY7
 | | Human Stimulator of Interferon Genes | | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, GLYCEROL, IMIDAZOLE, ... | | Authors: | Fernandez, D, Li, L, Ergun, S.L. | | Deposit date: | 2018-04-04 | | Release date: | 2019-03-13 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition.
Cell, 178, 2019
|
|
3R7W
 | | Crystal Structure of Gtr1p-Gtr2p complex | | Descriptor: | GTP-binding protein GTR1, GTP-binding protein GTR2, MAGNESIUM ION, ... | | Authors: | Gong, R, Li, L, Liu, Y, Wang, P, Yang, H, Wang, L, Cheng, J, Guan, K.L, Xu, Y. | | Deposit date: | 2011-03-23 | | Release date: | 2011-08-24 | | Last modified: | 2013-06-19 | | Method: | X-RAY DIFFRACTION (2.773 Å) | | Cite: | Crystal structure of the Gtr1p-Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation
Genes Dev., 25, 2011
|
|
2YBA
 | | Crystal structure of Nurf55 in complex with histone H3 | | Descriptor: | HISTONE H3, PROBABLE HISTONE-BINDING PROTEIN CAF1 | | Authors: | Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H. | | Deposit date: | 2011-03-02 | | Release date: | 2011-05-11 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks
Mol.Cell, 42, 2011
|
|
2YB8
 | | Crystal structure of Nurf55 in complex with Su(z)12 | | Descriptor: | POLYCOMB PROTEIN SU(Z)12, PROBABLE HISTONE-BINDING PROTEIN CAF1, SULFATE ION | | Authors: | Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H. | | Deposit date: | 2011-03-02 | | Release date: | 2011-05-18 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks.
Mol.Cell, 42, 2011
|
|
4K9R
 | | Spore photoproduct lyase Y98F mutant | | Descriptor: | IRON/SULFUR CLUSTER, SULFATE ION, Spore photoproduct lyase, ... | | Authors: | Yang, L, Nelson, R.S, Benjdia, A, Lin, G, Telser, J, Stoll, S, Schlichting, I, Li, L. | | Deposit date: | 2013-04-20 | | Release date: | 2013-05-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A radical transfer pathway in spore photoproduct lyase.
Biochemistry, 52, 2013
|
|
3B3D
 | | B.subtilis YtbE | | Descriptor: | CALCIUM ION, Putative morphine dehydrogenase | | Authors: | Zhou, Y.F, Li, L.F, Liang, Y.H, Su, X.-D. | | Deposit date: | 2007-10-20 | | Release date: | 2008-10-21 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and biochemical analyses of YvgN and YtbE from Bacillus subtilis
Protein Sci., 18, 2009
|
|
6LCP
 | | Cryo-EM structure of Dnf1 from Chaetomium thermophilum in the E2P state | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | He, Y, Xu, J, Wu, X, Li, L. | | Deposit date: | 2019-11-19 | | Release date: | 2020-04-29 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.48 Å) | | Cite: | Structures of a P4-ATPase lipid flippase in lipid bilayers.
Protein Cell, 11, 2020
|
|
7DRV
 | | Structural basis of SARS-CoV-2-closely-related bat coronavirus RaTG13 to hACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | Authors: | Liu, K.F, Pan, X.Q, Li, L.J, Feng, Y, Meng, Y.M, Zhang, Y.F, Wu, L.L, Chen, Q, Zheng, A.Q, Song, C.L, Jia, Y.F, Niu, S, Qiao, C.P, Zhao, X, Ma, D.L, Ma, X.P, Tan, S.G, Qi, J.X, Gao, G.F, Wang, Q.H. | | Deposit date: | 2020-12-29 | | Release date: | 2021-08-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.09 Å) | | Cite: | Binding and molecular basis of the bat coronavirus RaTG13 virus to ACE2 in humans and other species.
Cell, 184, 2021
|
|
8H95
 | | Structure of mouse SCMC bound with full-length FILIA | | Descriptor: | NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ... | | Authors: | Chi, P, Ou, G, Han, Z, Li, L, Deng, D. | | Deposit date: | 2022-10-24 | | Release date: | 2024-01-10 | | Last modified: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | Structural basis of the subcortical maternal complex and its implications in reproductive disorders.
Nat.Struct.Mol.Biol., 31, 2024
|
|
6LO8
 | | Cryo-EM structure of the TIM22 complex from yeast | | Descriptor: | Mitochondrial import inner membrane translocase subunit TIM10, Mitochondrial import inner membrane translocase subunit TIM12, Mitochondrial import inner membrane translocase subunit TIM18, ... | | Authors: | Zhang, Y, Zhou, X, Wu, X, Li, L. | | Deposit date: | 2020-01-04 | | Release date: | 2020-09-30 | | Last modified: | 2021-03-17 | | Method: | ELECTRON MICROSCOPY (3.83 Å) | | Cite: | Structure of the mitochondrial TIM22 complex from yeast.
Cell Res., 31, 2021
|
|
3O4O
 | | Crystal structure of an Interleukin-1 receptor complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 beta, ... | | Authors: | Wang, X.Q, Wang, D.L, Zhang, S.Y, Li, L, Liu, X, Mei, K.R. | | Deposit date: | 2010-07-27 | | Release date: | 2010-09-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structural insights into the assembly and activation of IL-1beta with its receptors
Nat.Immunol., 11, 2010
|
|
