3V6L
Crystal Structure of caspase-6 inactivation mutation
Summary for 3V6L
| Entry DOI | 10.2210/pdb3v6l/pdb |
| Related | 3NR2 3OD5 3V6M |
| Descriptor | Caspase-6 (2 entities in total) |
| Functional Keywords | apoptotic protease, caspase domain, hydrolase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P55212 |
| Total number of polymer chains | 2 |
| Total formula weight | 65146.33 |
| Authors | Cao, Q.,Wang, X.J.,Liu, D.F.,Li, L.F.,Su, X.D. (deposition date: 2011-12-20, release date: 2012-03-28, Last modification date: 2023-11-08) |
| Primary citation | Cao, Q.,Wang, X.J.,Liu, C.W.,Liu, D.F.,Li, L.F.,Gao, Y.Q.,Su, X.D. Inhibitory mechanism of caspase-6 phosphorylation revealed by crystal structures, molecular dynamics simulations, and biochemical assays J.Biol.Chem., 287:15371-15379, 2012 Cited by PubMed: 22433863DOI: 10.1074/jbc.M112.351213 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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