3MAZ
Crystal Structure of the Human BRDG1/STAP-1 SH2 Domain in Complex with the NTAL pTyr136 Peptide
Summary for 3MAZ
Entry DOI | 10.2210/pdb3maz/pdb |
Descriptor | Signal-transducing adaptor protein 1, CheD family protein, MALONATE ION, ... (4 entities in total) |
Functional Keywords | modular domain, phosphotyrosine, specificity, cytoplasm, phosphoprotein, sh2 domain, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm (Potential): Q9ULZ2 Cell membrane; Single-pass type III membrane protein: Q9GZY6 |
Total number of polymer chains | 2 |
Total formula weight | 15582.51 |
Authors | Kaneko, T.,Huang, H.,Zhao, B.,Li, L.,Liu, H.,Voss, C.K.,Wu, C.,Schiller, M.R.,Li, S.S. (deposition date: 2010-03-24, release date: 2010-05-12, Last modification date: 2023-11-22) |
Primary citation | Kaneko, T.,Huang, H.,Zhao, B.,Li, L.,Liu, H.,Voss, C.K.,Wu, C.,Schiller, M.R.,Li, S.S. Loops govern SH2 domain specificity by controlling access to binding pockets. Sci.Signal., 3:ra34-ra34, 2010 Cited by PubMed: 20442417DOI: 10.1126/scisignal.2000796 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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