3MAZ
Crystal Structure of the Human BRDG1/STAP-1 SH2 Domain in Complex with the NTAL pTyr136 Peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Signal-transducing adaptor protein 1 | polymer | 125 | 14180.1 | 1 | UniProt (Q9ULZ2) Pfam (PF00017) In PDB | Homo sapiens (human) | STAP-1, Stem cell adaptor protein 1, BCR downstream-signaling protein 1, Docking protein BRDG1 |
2 | B | CheD family protein | polymer | 12 | 1300.4 | 1 | UniProt (Q9GZY6) In PDB | ||
3 | A | MALONATE ION | non-polymer | 102.0 | 1 | Chemie (MLI) | |||
4 | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence modifications
A: 167 - 285 (UniProt: Q9ULZ2)
B: 133 - 143 (UniProt: Q9GZY6)
PDB | External Database | Details |
---|---|---|
Gly 161 | - | expression tag |
Ser 162 | - | expression tag |
Gly 163 | - | expression tag |
Arg 164 | - | expression tag |
Ala 165 | - | expression tag |
Met 166 | - | expression tag |
Ala 269 | Cys 269 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ala 142 | Cys 142 | engineered mutation |
Nh2 144 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 15480.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 102.0 | |
All* | Total formula weight | 15582.5 |