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PDB: 1804 件
7YI4
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Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in close state
分子名称: Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ...
著者Li, H.T, Yan, C.Y, Guan, H.P, Wang, P.
登録日2022-07-14
公開日2023-06-14
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023
2OJE
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BU of 2oje by Molmil
Mycoplasma arthritidis-derived mitogen complexed with class II MHC molecule HLA-DR1/HA complex in the presence of EDTA
分子名称: HLA class II histocompatibility antigen, DR alpha chain precursor, DRB1-1 beta chain precursor, ...
著者Li, H, Zhao, Y, Guo, Y, Li, Z, Eisele, L, Mourad, W.
登録日2007-01-12
公開日2007-01-23
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Zinc induces dimerization of the class II major histocompatibility complex molecule that leads to cooperative binding to a superantigen.
J.Biol.Chem., 282, 2007
1DQQ
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BU of 1dqq by Molmil
CRYSTAL STRUCTURE OF ANTI-LYSOZYME ANTIBODY HYHEL-63
分子名称: ANTI-LYSOZYME ANTIBODY HYHEL-63 (HEAVY CHAIN), ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN)
著者Li, H, Mariuzza, R.A.
登録日2000-01-04
公開日2000-01-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,).
Biochemistry, 39, 2000
2OY0
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BU of 2oy0 by Molmil
Crystal structure of the West Nile virus methyltransferase
分子名称: Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Li, H.M, Zhao, Y.W, Guo, Y, Shi, P.Y.
登録日2007-02-21
公開日2007-04-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and Function of Flavivirus NS5 Methyltransferase.
J.Virol., 81, 2007
1LZZ
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BU of 1lzz by Molmil
Rat neuronal NOS heme domain with N-isopropyl-N'-hydroxyguanidine bound
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-ISOPROPYL-N'-HYDROXYGUANIDINE, ...
著者Li, H, Shimizu, H, Flinspach, M, Jamal, J, Yang, W, Xian, M, Cai, T, Wen, E.Z, Jia, Q, Wang, P.G, Poulos, T.L.
登録日2002-06-11
公開日2002-11-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41, 2002
1LZX
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BU of 1lzx by Molmil
Rat neuronal NOS heme domain with NG-hydroxy-L-arginine bound
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-OMEGA-HYDROXY-L-ARGININE, ...
著者Li, H, Shimizu, H, Flinspach, M, Jamal, J, Yang, W, Xian, M, Cai, T, Wen, E.Z, Jia, Q, Wang, P.G, Poulos, T.L.
登録日2002-06-11
公開日2002-11-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41, 2002
2NAE
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BU of 2nae by Molmil
Membrane-bound mouse CD28 cytoplasmic tail
分子名称: T-cell-specific surface glycoprotein CD28
著者Li, H, Xu, C, Pan, W.
登録日2015-12-23
公開日2016-12-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Dynamic regulation of CD28 conformation and signaling by charged lipids and ions.
Nat.Struct.Mol.Biol., 24, 2017
4V3W
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BU of 4v3w by Molmil
Structure of rat neuronal nitric oxide synthase heme domain in complex with 2-(2-(1H-imidazol-1-yl)pyrimidin-4-yl)-N-(3- fluorophenethyl)ethan-1-amine
分子名称: 2-(3-fluorophenyl)-N-{2-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]ethyl}ethanamine, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ...
著者Li, H, Poulos, T.L.
登録日2014-10-20
公開日2014-12-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Novel 2,4-Disubstituted Pyrimidines as Potent, Selective, and Cell-Permeable Inhibitors of Neuronal Nitric Oxide Synthase.
J.Med.Chem., 58, 2015
4V3X
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BU of 4v3x by Molmil
Structure of rat neuronal nitric oxide synthase heme domain in complex with N-2-(2-(1H-imidazol-1-yl)pyrimidin-4-yl)ethyl-3-(3- fluorophenyl)propan-1-amine
分子名称: 3-(3-fluorophenyl)-N-{2-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]ethyl}propan-1-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ...
著者Li, H, Poulos, T.L.
登録日2014-10-20
公開日2014-12-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Novel 2,4-Disubstituted Pyrimidines as Potent, Selective, and Cell-Permeable Inhibitors of Neuronal Nitric Oxide Synthase.
J.Med.Chem., 58, 2015
3P6Y
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BU of 3p6y by Molmil
CF Im25-CF Im68-UGUAA complex
分子名称: 5'-R(*UP*GP*UP*AP*A)-3', Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6
著者Li, H, Tong, S, Li, X, Shi, H, Gao, Y, Ge, H, Niu, L, Teng, M.
登録日2010-10-11
公開日2010-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of pre-mRNA recognition by the human cleavage factor Im complex
To be Published
3P5T
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BU of 3p5t by Molmil
CFIm25-CFIm68 complex
分子名称: Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6
著者Li, H, Tong, S, Li, X, Shi, H, Gao, Y, Ge, H, Niu, L, Teng, M.
登録日2010-10-11
公開日2010-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of pre-mRNA recognition by the human cleavage factor Im complex
To be Published
1FAH
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BU of 1fah by Molmil
STRUCTURE OF CYTOCHROME P450
分子名称: CYTOCHROME P450 BM-3, PROTOPORPHYRIN IX CONTAINING FE
著者Li, H.Y, Poulos, T.L.
登録日1996-08-01
公開日1997-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The role of Thr268 in oxygen activation of cytochrome P450BM-3.
Biochemistry, 34, 1995
1DQM
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BU of 1dqm by Molmil
CRYSTAL STRUCTURE OF ANTI-LYSOZYME ANTIBODY
分子名称: ANTI-LYSOZYME ANTIBODY HYHEL-63 (HEAVY CHAIN), ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN)
著者Li, H, Mariuzza, R.A.
登録日2000-01-04
公開日2000-01-19
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,).
Biochemistry, 39, 2000
3MD1
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BU of 3md1 by Molmil
Crystal Structure of the Second RRM Domain of Yeast Poly(U)-Binding Protein (Pub1)
分子名称: GLYCEROL, Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1
著者Li, H, Shi, H, Li, Y, Cui, Y, Niu, L, Teng, M.
登録日2010-03-29
公開日2010-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of the Second RRM Domain of Yeast Poly(U)-Binding Protein (Pub1)
To be published
6LN1
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BU of 6ln1 by Molmil
A natural inhibitor of DYRK1A for treatment of diabetes mellitus
分子名称: 1,3,5,8-tetrakis(oxidanyl)xanthen-9-one, Dual specificity tyrosine-phosphorylation-regulated kinase 1A
著者Li, H, Chen, L.X, Zheng, M.Z, Zhang, Q.Z, Zhang, C.L, Wu, C.R, Yang, K.Y, Song, Z.R, Wang, Q.Q, Li, C, Zhou, Y.R, Chen, J.C.
登録日2019-12-28
公開日2021-10-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.699 Å)
主引用文献A natural DYRK1A inhibitor as a potential stimulator for beta-cell proliferation in diabetes.
Clin Transl Med, 11, 2021
3T88
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BU of 3t88 by Molmil
Crystal structure of Escherichia coli MenB in complex with substrate analogue, OSB-NCoA
分子名称: 1,4-Dihydroxy-2-naphthoyl-CoA synthase, CHLORIDE ION, GLYCEROL, ...
著者Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P.
登録日2011-08-01
公開日2011-08-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member.
Biochemistry, 50, 2011
3T8A
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BU of 3t8a by Molmil
Crystal structure of Mycobacterium tuberculosis MenB in complex with substrate analogue, OSB-NCoA
分子名称: 1,4-Dihydroxy-2-naphthoyl-CoA synthase, o-succinylbenzoyl-N-coenzyme A
著者Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P.
登録日2011-08-01
公開日2011-08-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.245 Å)
主引用文献Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member.
Biochemistry, 50, 2011
1DQJ
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BU of 1dqj by Molmil
CRYSTAL STRUCTURE OF THE ANTI-LYSOZYME ANTIBODY HYHEL-63 COMPLEXED WITH HEN EGG WHITE LYSOZYME
分子名称: ANTI-LYSOZYME ANTIBODY HYHEL-63 (HEAVY CHAIN), ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN), LYSOZYME
著者Li, H, Mariuzza, R.A.
登録日2000-01-04
公開日2000-01-19
最終更新日2021-07-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,).
Biochemistry, 39, 2000
1K2T
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BU of 1k2t by Molmil
Structure of rat brain nNOS heme domain complexed with S-ethyl-N-phenyl-isothiourea
分子名称: 2-ETHYL-1-PHENYL-ISOTHIOUREA, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ...
著者Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L, Raman, C.S.
登録日2001-09-28
公開日2003-03-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of rat brain nNOS heme domain
To be Published
1K2U
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BU of 1k2u by Molmil
Structure of rat brain nNOS heme domain complexed with S-ethyl-N-[4-(trifluoromethyl)phenyl] isothiourea
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L, Raman, C.S.
登録日2001-09-28
公開日2003-03-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of rat brain nNOS heme domain
To be Published
3T89
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BU of 3t89 by Molmil
Crystal structure of Escherichia coli MenB, the 1,4-dihydroxy-2-naphthoyl-CoA synthase in vitamin K2 biosynthesis
分子名称: 1,4-Dihydroxy-2-naphthoyl-CoA synthase, GLYCEROL, MALONATE ION
著者Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P.
登録日2011-08-01
公開日2011-08-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member.
Biochemistry, 50, 2011
6CFW
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BU of 6cfw by Molmil
cryoEM structure of a respiratory membrane-bound hydrogenase
分子名称: IRON/SULFUR CLUSTER, MBH subunit, Mbh13 NADH dehydrogenase subunit, ...
著者Li, H.L, Yu, H.J.
登録日2018-02-17
公開日2018-05-23
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of an Ancient Respiratory System.
Cell, 173, 2018
5EIB
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BU of 5eib by Molmil
Crystal structure of CPAP PN2-3 C-terminal loop-helix in complex with DARPin-tubulin
分子名称: Designed ankyrin repeat protein, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Li, H, Zheng, X.
登録日2015-10-29
公開日2016-10-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length
Nat Commun, 7, 2016
1K2R
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BU of 1k2r by Molmil
Structure of rat brain nNOS heme domain complexed with NG-nitro-L-arginine
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-OMEGA-NITRO-L-ARGININE, ...
著者Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L, Raman, C.S.
登録日2001-09-28
公開日2003-03-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of rat brain nNOS heme domain
To be Published
1K2S
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BU of 1k2s by Molmil
Structure of rat brain nNOS heme domain complexed with NG-allyl-L-arginine
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 5-N-ALLYL-ARGININE, ACETATE ION, ...
著者Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L, Raman, C.S.
登録日2001-09-28
公開日2003-03-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of rat brain nNOS heme domain
To be Published

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件を2024-10-30に公開中

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