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PDB: 235 件

6A9N
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Crystal structure of KAS III from Propionibacterium acnes
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 3, GLYCEROL, POTASSIUM ION
著者Lee, W.C, Cheon, D, Kim, Y.
登録日2018-07-14
公開日2019-07-17
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Crystal structure of KAS III from Propionibacterium acnes
to be published
7F28
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Crystal structure of a bacterial ketosynthase
分子名称: Ketoacyl_synth_N domain-containing protein, Putative 3-oxoacyl-[ACP] synthase FabV
著者Lee, W.C, Kim, Y.
登録日2021-06-10
公開日2022-06-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.877 Å)
主引用文献Structural basis of the complementary activity of two ketosynthases in aryl polyene biosynthesis.
Sci Rep, 11, 2021
2MVF
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Structural insight into an essential assembly factor network on the pre-ribosome
分子名称: Uncharacterized protein
著者Lee, W, Bassler, J, Paternoga, H, Holdermann, I, Thomas, M, Granneman, S, Barrio-Garcia, C, Nyarko, A, Stier, G, Clark, S.A, Schraivogel, D, Kallas, M, Beckmann, R, Tollervey, D, Barbar, E, Sinning, I, Hurt, E.
登録日2014-10-02
公開日2014-12-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation.
J.Cell Biol., 207, 2014
5J4F
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Crystal structure of the N-terminally His6-tagged HP0902, an uncharacterized protein from Helicobacter pylori 26695
分子名称: Uncharacterized protein
著者Sim, D.-W, Lee, W.-C, Kim, H.Y, Kim, J.-H, Won, H.-S.
登録日2016-04-01
公開日2017-02-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural identification of the lipopolysaccharide-binding capability of a cupin-family protein from Helicobacter pylori
FEBS Lett., 590, 2016
7LHQ
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Solution structure of SARS-CoV-2 nonstructural protein 7 at pH 7.0
分子名称: Non-structural protein 7
著者Lee, Y, Tonelli, M, Anderson, T.K, Kirchdoerfer, R.N, Henzler-Wildman, K, Lee, W.
登録日2021-01-26
公開日2022-02-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献pH-dependent polymorphism of the structure of SARS-CoV-2 nsp7
Biorxiv, 2021
3KKL
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Crystal structure of functionally unknown HSP33 from Saccharomyces cerevisiae
分子名称: Probable chaperone protein HSP33
著者Hwang, K.Y, Sung, M.W, Lee, W.H.
登録日2009-11-05
公開日2010-03-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal structure of functionally unknown HSP33 from Saccharomyces cerevisiae
To be Published
1R02
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Solution structure of Human Orexin-A:Regulator of Appetite and Wakefulness
分子名称: Orexin-A
著者Kim, H.-Y, Hong, E, Kim, J.-I, Lee, W.
登録日2003-09-19
公開日2004-09-19
最終更新日2024-10-23
実験手法SOLUTION NMR
主引用文献Solution structure of human orexin-A: regulator of appetite and wakefulness.
J.Biochem.Mol.Biol., 37, 2004
6MW6
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Antimicrobial lasso peptide citrocin
分子名称: Citrocin
著者Link, A.J, Cheung-Lee, W.L.
登録日2018-10-29
公開日2019-03-13
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Discovery and structure of the antimicrobial lasso peptide citrocin.
J.Biol.Chem., 294, 2019
2ABY
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BU of 2aby by Molmil
Solution structure of TA0743 from Thermoplasma acidophilum
分子名称: hypothetical protein TA0743
著者Kim, B, Jung, J, Hong, E, Yee, A, Arrowsmith, C.H, Lee, W.
登録日2005-07-18
公開日2006-08-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure of the conserved novel-fold protein TA0743 from Thermoplasma acidophilum.
Proteins, 62, 2006
6POR
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Antimicrobial lasso peptide ubonodin
分子名称: Ubonodin
著者Link, A.J, Cheung-Lee, W.L.
登録日2019-07-05
公開日2019-12-04
最終更新日2024-10-23
実験手法SOLUTION NMR
主引用文献Discovery of Ubonodin, an Antimicrobial Lasso Peptide Active against Members of the Burkholderia cepacia Complex.
Chembiochem, 21, 2020
6Q1X
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Lasso peptide pandonodin
分子名称: Pandonodin
著者Link, A.J, Cheung-Lee, W.L.
登録日2019-08-06
公開日2019-12-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Pandonodin: A Proteobacterial Lasso Peptide with an Exceptionally Long C-Terminal Tail.
Acs Chem.Biol., 14, 2019
8Y4Z
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Monomeric HERC5 HECT c-lobe structure in solution
分子名称: E3 ISG15--protein ligase HERC5
著者Dag, C, Lambert, M, Kahraman, K, Lohn, F, Lee, W, Gocenler, O, Guntert, P, Dotsch, V.
登録日2024-01-31
公開日2024-02-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Monomeric HERC5 HECT c-lobe structure in solution
To Be Published
8SVB
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Antimicrobial lasso peptide achromonodin-1
分子名称: Achromonodin-1
著者Carson, D.V, Cheung-Lee, W.L, So, L, Link, A.J.
登録日2023-05-16
公開日2023-10-11
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献Discovery, Characterization, and Bioactivity of the Achromonodins: Lasso Peptides Encoded by Achromobacter .
J.Nat.Prod., 86, 2023
6L7Z
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Solution NMR structure of the N-terminal immunoglobulin variable domain of BTNL2
分子名称: Butyrophilin-like protein 2
著者Basak, A.J, Lee, W, Samanta, D, De, S.
登録日2019-11-03
公開日2020-10-14
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural Insights into N-terminal IgV Domain of BTNL2, a T Cell Inhibitory Molecule, Suggests a Non-canonical Binding Interface for Its Putative Receptors.
J.Mol.Biol., 432, 2020
6T8W
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Complement factor B in complex with (-)-4-(1-((5,7-Dimethyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic acid
分子名称: 5,7-dimethyl-4-[[(2~{S})-2-phenylpiperidin-1-yl]methyl]-1~{H}-indole, Complement factor B, SULFATE ION, ...
著者Mainolfi, N, Ehara, T, Karki, R.G, Anderson, K, Sweeney, A.M, Wiesmann, C, Adams, C, Mainolfi, N, Liao, S.M, Argikar, U.A, Jendza, K, Zhang, C, Powers, J, Klosowski, D.W, Crowley, M, Kawanami, T, Ding, J, April, M, Forster, C, Wu, M.S, Capparelli, M, Ramqaj, R, Solovay, C, Cumin, F, Smith, T.M, Ferrara, L, Lee, W, Long, D, Prentiss, M, Erkenez, A.D, Yang, L, Fang, L, Sellner, H, Sirockin, F, Valeur, E, Erbel, P, Ramage, P, Gerhartz, B, Schubart, A, Flohr, S, Gradoux, N, Feifel, R, Vogg, B, Wiesmann, C, Maibaum, J, Eder, J, Sedrani, R, Harrison, R.A, Mogi, M, Jaffee, B.D, Adams, C.M.
登録日2019-10-25
公開日2020-03-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases.
J.Med.Chem., 63, 2020
6T8U
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BU of 6t8u by Molmil
Complement factor B in complex with 5-Bromo-3-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-7-methyl-1H-indol-4-amine
分子名称: 5-bromanyl-3-chloranyl-~{N}-(1~{H}-imidazol-2-yl)-7-methyl-1~{H}-indol-4-amine, Complement factor B, SULFATE ION
著者Mainolfi, N, Ehara, T, Karki, R.G, Anderson, K, Mac Sweeney, A, Wiesmann, C, Adams, C, Liao, S.-M, Argikar, U.A, Jendza, K, Zhang, C, Powers, J, Klosowski, D.W, Crowley, M, Kawanami, T, Ding, J, April, M, Forster, C, Serrano-Wu, M, Capparelli, M, Ramqaj, R, Solovay, C, Cumin, F, Smith, T.M, Ferrara, L, Lee, W, Long, D, Prentiss, M, De Erkenez, A, Yang, L, Fang, L, Sellner, H, Sirockin, F, Valeur, E, Erbel, P, Ramage, P, Gerhartz, B, Schubart, A, Flohr, S, Gradoux, N, Feifel, R, Vogg, B, Maibaum, J, Eder, J, Sedrani, R, Harrison, R.A, Mogi, M, Jaffee, B.D, Adams, C.M.
登録日2019-10-25
公開日2020-03-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases.
J.Med.Chem., 63, 2020
6T8V
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BU of 6t8v by Molmil
Complement factor B in complex with (S)-5,7-Dimethyl-4-((2-phenylpiperidin-1-yl)methyl)-1H-indole
分子名称: 4-[(2~{S})-1-[(5,7-dimethyl-1~{H}-indol-4-yl)methyl]piperidin-2-yl]benzoic acid, Complement factor B, SULFATE ION, ...
著者Mainolfi, N, Ehara, T, Karki, R.G, Anderson, K, Mac Sweeney, A, Wiesmann, C, Adams, C, Mainolfi, N, Liao, S.-M, Argikar, U.A, Jendza, K, Zhang, C, Powers, J, Klosowski, D.W, Crowley, M, Kawanami, T, Ding, J, April, M, Forster, C, Serrano-Wu, M, Capparelli, M, Ramqaj, R, Solovay, C, Cumin, F, Smith, T.M, Ferrara, L, Lee, W, Long, D, Prentiss, M, De Erkenez, A, Yang, L, Fang, L, Sellner, H, Sirockin, F, Valeur, E, Erbel, P, Ramage, P, Gerhartz, B, Schubart, A, Flohr, S, Gradoux, N, Feifel, R, Vogg, B, Wiesmann, C, Maibaum, J, Eder, J, Sedrani, R, Harrison, R.A, Mogi, M, Jaffee, B.D, Adams, C.M.
登録日2019-10-25
公開日2020-03-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases.
J.Med.Chem., 63, 2020
5J4G
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BU of 5j4g by Molmil
Crystal structure of the C-terminally His6-tagged HP0902, an uncharacterized protein from Helicobacter pylori 26695
分子名称: Uncharacterized protein
著者Sim, D.W, Lee, W.C, Kim, H.Y, Kim, J.H, Won, H.S.
登録日2016-04-01
公開日2017-02-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural identification of the lipopolysaccharide-binding capability of a cupin-family protein from Helicobacter pylori
FEBS Lett., 590, 2016
1CQ0
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SOLUTION STRUCTURE OF A HUMAN HYPOCRETIN-2/OREXIN-B'SOLUTION STRUCTURE OF A HUMAN HYPOCRETIN-2/OREXIN-B '
分子名称: PROTEIN (NEW HYPOTHALAMIC NEUROPEPTIDE/OREXIN-B28)
著者Lee, K.-H, Bang, E.J, Chae, K.-J, Lee, D.W, Lee, W.
登録日1999-08-04
公開日2000-01-10
最終更新日2024-04-10
実験手法SOLUTION NMR
主引用文献Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B.
Eur.J.Biochem., 266, 1999
1MNL
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HIGH-RESOLUTION SOLUTION STRUCTURE OF A SWEET PROTEIN SINGLE-CHAIN MONELLIN (SCM) DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND DYNAMICAL SIMULATED ANNEALING CALCULATIONS, 21 STRUCTURES
分子名称: MONELLIN
著者Lee, S.-Y, Lee, J.-H, Chang, H.-J, Jo, J.-M, Jung, J.-W, Lee, W.
登録日1998-08-06
公開日1999-06-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of a sweet protein single-chain monellin determined by nuclear magnetic resonance and dynamical simulated annealing calculations.
Biochemistry, 38, 1999
6X6N
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NMR structure of the putative GTPase-Activating (GAP) domain of VopE
分子名称: Outer membrane virulence protein yopE
著者Smith, K.P, Lee, W, Tonelli, M.
登録日2020-05-28
公開日2021-12-22
最終更新日2024-05-15
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Solution structure and dynamics of the mitochondrial-targeted GTPase-activating protein (GAP) VopE by an integrated NMR/SAXS approach.
Protein Sci., 31, 2022
1RYJ
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BU of 1ryj by Molmil
Solution NMR Structure of Protein Mth1743 from Methanobacterium thermoautotrophicum. Ontario Centre for Structural Proteomics target MTH1743_1_70; Northeast Structural Genomics Consortium Target TT526.
分子名称: unknown
著者Yee, A, Chang, X, Pineda-Lucena, A, Wu, B, Semesi, A, Le, B, Ramelot, T, Lee, G.M, Bhattacharyya, S, Gutierrez, P, Denisov, A, Lee, C.H, Cort, J.R, Kozlov, G, Liao, J, Finak, G, Chen, L, Wishart, D, Lee, W, McIntosh, L.P, Gehring, K, Kennedy, M.A, Edwards, A.M, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG)
登録日2003-12-22
公開日2004-02-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献AN NMR APPROACH TO STRUCTURAL PROTEOMICS
Proc.Natl.Acad.Sci.USA, 99, 2002
1RJA
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Solution Structure and Backbone Dynamics of the Nonreceptor Tyrosine Kinase PTK6/Brk SH2 Domain
分子名称: Tyrosine-protein kinase 6
著者Hong, E, Shin, J, Lee, W.
登録日2003-11-18
公開日2004-07-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution Structure and Backbone Dynamics of the Non-receptor Protein-tyrosine Kinase-6 Src Homology 2 Domain
J.Biol.Chem., 279, 2004
6O6W
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Solution structure of human myeloid-derived growth factor
分子名称: Myeloid-derived growth factor
著者Bortnov, V, Tonelli, M, Lee, W, Markley, J.L, Mosher, D.F.
登録日2019-03-07
公開日2019-11-13
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution structure of human myeloid-derived growth factor suggests a conserved function in the endoplasmic reticulum.
Nat Commun, 10, 2019
1IQO
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BU of 1iqo by Molmil
Solution structure of MTH1880 from methanobacterium thermoautotrophicum
分子名称: HYPOTHETICAL PROTEIN MTH1880
著者Lee, C.H, Shin, J, Bang, E, Jung, J.W, Yee, A, Arrowsmith, C.H, Lee, W.
登録日2001-07-23
公開日2002-07-24
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of a novel calcium binding protein, MTH1880, from Methanobacterium thermoautotrophicum.
Protein Sci., 13, 2004

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