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PDB: 312 results

4Z6C
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Structure of human DNA polymerase beta 279NA mutant complexed with G in the template base paired with incoming non-hydrolyzable CTP
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Koag, M.-C, Lee, S.
Deposit date:2015-04-04
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.677 Å)
Cite:Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase beta.
Biochem. J., 475, 2018
4Z6D
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BU of 4z6d by Molmil
Structure of human DNA polymerase beta 279NA mutant complexed with G in the template base paired with incoming non-hydrolyzable TTP
Descriptor: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Koag, M.-C, Lee, S.
Deposit date:2015-04-04
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase beta.
Biochem. J., 475, 2018
7TFM
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Atomic Structure of the Leishmania spp. Hsp100 N-Domain
Descriptor: ATP-dependent Clp protease subunit, heat shock protein 100 (HSP100), GLYCEROL
Authors:Mercado, J.M, Lee, S, Chang, C, Sung, N, Soong, L, Catic, A, Tsai, F.T.F.
Deposit date:2022-01-06
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.055 Å)
Cite:Atomic structure of the Leishmania spp. Hsp100 N-domain.
Proteins, 90, 2022
3OGD
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BU of 3ogd by Molmil
AlkA Undamaged DNA Complex: Interrogation of a G*:C base pair
Descriptor: 5'-D(*CP*AP*(BRU)P*GP*AP*CP*(BRU)P*GP*C)-3', 5'-D(*GP*CP*AP*GP*TP*CP*AP*TP*G)-3', DNA-3-methyladenine glycosylase 2
Authors:Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
Deposit date:2010-08-16
Release date:2010-09-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Escherichia coli AlkA in Complex with Undamaged DNA.
J.Biol.Chem., 285, 2010
4YPR
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Crystal Structure of D144N MutY bound to its anti-substrate
Descriptor: A/G-specific adenine glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(*T*GP*TP*CP*CP*AP*CP*GP*TP*CP*T)-3'), ...
Authors:Wang, L, Lee, S, Verdine, G.L.
Deposit date:2015-03-13
Release date:2015-05-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase.
J.Biol.Chem., 290, 2015
4YPH
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Crystal Structure of MutY bound to its anti-substrate with the disulfide cross-linker reduced
Descriptor: A/G-specific adenine glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(TP*GP*TP*CP*CP*AP*CP*GP*TP*CP*T)-3'), ...
Authors:Wang, L, Lee, S, Verdine, G.L.
Deposit date:2015-03-12
Release date:2015-05-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase.
J.Biol.Chem., 290, 2015
3C9B
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Crystal structure of SeMet Vps75
Descriptor: Vacuolar protein sorting-associated protein 75
Authors:Keck, J.L, Berndsen, C.E, Tsubota, T, Lindner, S.E, Lee, S, Holton, J.M, Kaufman, P.D, Denu, J.M.
Deposit date:2008-02-15
Release date:2008-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75
Nat.Struct.Mol.Biol., 15, 2008
4YOQ
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Crystal Structure of MutY bound to its anti-substrate
Descriptor: A/G-specific adenine glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(*T*GP*TP*CP*CP*AP*CP*GP*TP*CP*T)-3'), ...
Authors:Wang, L, Lee, S, Verdine, G.L.
Deposit date:2015-03-11
Release date:2015-05-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase.
J.Biol.Chem., 290, 2015
2AG4
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Crystal Structure Analysis of GM2-activator protein complexed with phosphatidylcholine
Descriptor: (7R)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM 4-OXIDE, Ganglioside GM2 activator, ISOPROPYL ALCOHOL, ...
Authors:Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F.
Deposit date:2005-07-26
Release date:2005-10-25
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2AG9
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Crystal Structure of the Y137S mutant of GM2-Activator Protein
Descriptor: Ganglioside GM2 activator, ISOPROPYL ALCOHOL, MYRISTIC ACID
Authors:Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F.
Deposit date:2005-07-26
Release date:2005-10-25
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2AGC
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Crystal Structure of mouse GM2- activator Protein
Descriptor: Ganglioside GM2 activator, LAURIC ACID, MYRISTIC ACID
Authors:Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F.
Deposit date:2005-07-26
Release date:2005-10-25
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
5IS1
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BU of 5is1 by Molmil
Crystal structure of the extracellular domain of sensor histidine kinase YycG from Staphylococcus aureus at 2.0 Angstrom resolution
Descriptor: Histidine kinase
Authors:Kim, T, Choi, J, Lee, S, Kim, K.K.
Deposit date:2016-03-15
Release date:2016-07-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Structural Studies on the Extracellular Domain of Sensor Histidine Kinase YycG from Staphylococcus aureus and Its Functional Implications
J.Mol.Biol., 428, 2016
1YD8
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BU of 1yd8 by Molmil
COMPLEX OF HUMAN GGA3 GAT DOMAIN AND UBIQUITIN
Descriptor: ADP-RIBOSYLATION FACTOR BINDING PROTEIN GGA3, UBIQUIN
Authors:Prag, G, Lee, S, Mattera, R, Arighi, C.N, Beach, B.M, Bonifacino, J.S, Hurley, J.H.
Deposit date:2004-12-23
Release date:2005-02-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural mechanism for ubiquitinated-cargo recognition by the Golgi-localized, {gamma}-ear-containing, ADP-ribosylation-factor-binding proteins
Proc.Natl.Acad.Sci.USA, 102, 2005
2F6M
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BU of 2f6m by Molmil
Structure of a Vps23-C:Vps28-N subcomplex
Descriptor: DECYLAMINE-N,N-DIMETHYL-N-OXIDE, MAGNESIUM ION, Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, ...
Authors:Kostelansky, M.S, Lee, S, Kim, J, Hurley, J.H.
Deposit date:2005-11-29
Release date:2006-04-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and functional organization of the ESCRT-I trafficking complex.
Cell(Cambridge,Mass.), 125, 2006
4OFH
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BU of 4ofh by Molmil
Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis
Descriptor: 12-mer DNA(O6MeG), 12-mer DNA(T), MAGNESIUM ION, ...
Authors:Ouzon-Shubeita, H, Lin, Y.-L, Lee, S.
Deposit date:2014-01-14
Release date:2015-04-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structure of MBD4 bound to O6MeG:T mispair DNA
To be Published
4F4B
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Structure of OSH4 with a cholesterol analog
Descriptor: (3beta,9beta,25R)-3-hydroxy-26-iodocholest-5-ene-16,22-dione, Protein KES1
Authors:Koag, M.C, Monzingo, A.F, Cheun, Y, Lee, S.
Deposit date:2012-05-10
Release date:2013-05-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4.
Steroids, 78, 2013
4FD2
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BU of 4fd2 by Molmil
Crystal structure of the C-terminal domain of ClpB
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB
Authors:Biter, A.B, Lee, S, Sung, N, Tsai, F.T.F.
Deposit date:2012-05-25
Release date:2012-07-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for intersubunit signaling in a protein disaggregating machine.
Proc.Natl.Acad.Sci.USA, 109, 2012
4J4K
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BU of 4j4k by Molmil
Crystal structure of glucose isomerase
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, Xylose isomerase, ...
Authors:Kim, M.K, An, Y.J, Lee, S, Jeong, C.S, Cha, S.S.
Deposit date:2013-02-07
Release date:2014-04-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of glucose isomerase
To be Published
5CHZ
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BU of 5chz by Molmil
Structure of wild-type human MBD4 bound to a G:T mismatch
Descriptor: 12-mer DNA(G), 5-mer DNA, 7-mer DNA, ...
Authors:Ouzon-Shubeita, H, Lin, Y.-L, Lee, S.
Deposit date:2015-07-10
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure of wild-type human MBD4 bound to a G:T mismatch
To Be Published
4PHE
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BU of 4phe by Molmil
Structure of human DNA polymerase beta complexed with T in the template base paired with incoming non-hydrolyzable GTP
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2014-05-06
Release date:2015-05-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The spontaneous base substitution mechanisms of human DNA polymerase beta
To Be Published
4O5C
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Structure of human DNA polymerase complexed with N7-MG as the template base in a 1-nucleotide gapped DNA
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2013-12-19
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.363 Å)
Cite:Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine.
Nucleic Acids Res., 42, 2014
5DBA
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Structure of human DNA polymerase beta Host-Guest complex with the dG base paired with a dT
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-21
Release date:2015-11-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.965 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
4O5E
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BU of 4o5e by Molmil
Structure of human DNA polymerase complexed with N7MG in the template base paired with incoming non-hydrolyzable TTP
Descriptor: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2013-12-19
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.532 Å)
Cite:Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine.
Nucleic Acids Res., 42, 2014
4O5K
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Structure of human DNA polymerase complexed with N7MG in the template base paired with incoming non-hydrolyzable CTP
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2013-12-19
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.058 Å)
Cite:Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine.
Nucleic Acids Res., 42, 2014
4NLN
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BU of 4nln by Molmil
Structure of human DNA polymerase beta complexed with nicked DNA containing a template 8BrG and incoming CTP
Descriptor: 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
Authors:Koag, M.-C, Min, K, Monzingo, A.F, Lee, S.
Deposit date:2013-11-14
Release date:2014-01-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.261 Å)
Cite:Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014

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