4WHL
 
 | | A New Class of Peptidomimetics Targeting the Polo-box Domain of Polo-like kinase 1 | | 分子名称: | C6H5(CH2)8-DERIVATIZED PEPTIDE INHIBITOR, Serine/threonine-protein kinase PLK1 | | 著者 | Bang, J.K, Han, Y.H, Ahn, M.J, Lee, K.S. | | 登録日 | 2014-09-23 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | A new class of peptidomimetics targeting the polo-box domain of polo-like kinase 1.
J.Med.Chem., 58, 2015
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8D87
 | | Fitted crystal structure of the homotrimer of fusion glycoprotein E1 from SFV into subtomogram averaged CHIKV E1 glycoprotein density | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Mangala Prasad, V, Lee, K.K. | | 登録日 | 2022-06-08 | | 公開日 | 2022-08-31 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (27.200001 Å) | | 主引用文献 | Visualization of conformational changes and membrane remodeling leading to genome delivery by viral class-II fusion machinery.
Nat Commun, 13, 2022
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3NJ4
 | | Fluoro-neplanocin A in Human S-Adenosylhomocysteine Hydrolase | | 分子名称: | (4S,5S)-4-(6-amino-9H-purin-9-yl)-3-fluoro-5-hydroxy-2-(hydroxymethyl)cyclopent-2-en-1-one, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Jeong, L.S, Lee, K.M, Hwang, K.Y, Choi, S, Heo, Y.S. | | 登録日 | 2010-06-17 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analogues.
J.Med.Chem., 54, 2011
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9FLU
 | | CryoEM structure of the fragment-1 (3402-3733) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-06-05 | | 公開日 | 2024-10-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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9FLX
 | | CryoEM structure of the fragment-4 (4074-4421) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-06-05 | | 公開日 | 2024-10-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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9G8B
 | | CryoEM structure of the fragment-2 (2892-3236) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-07-23 | | 公開日 | 2024-10-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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9FLV
 | | CryoEM structure of the fragment-5 (2393-2807) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-06-05 | | 公開日 | 2024-10-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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9FLS
 | | CryoEM structure of the fragment-3 (2061-2397) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-06-05 | | 公開日 | 2024-10-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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9FLW
 | | CryoEM structure of the fragment-6 (3571-4078) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-06-05 | | 公開日 | 2024-10-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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9FLP
 | | CryoEM structure of the neck (1403-2314) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-06-05 | | 公開日 | 2024-10-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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9FLY
 | | CryoEM structure of the base (4151-5009) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-06-05 | | 公開日 | 2024-10-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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4QXZ
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1JXV
 | | Crystal Structure of Human Nucleoside Diphosphate Kinase A | | 分子名称: | Nucleoside Diphosphate Kinase A | | 著者 | Min, K, Song, H.K, Chang, C, Kim, S.Y, Lee, K.J, Suh, S.W. | | 登録日 | 2001-09-10 | | 公開日 | 2002-04-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of human nucleoside diphosphate kinase A, a metastasis suppressor.
Proteins, 46, 2002
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6CSV
 | | The structure of the Cep63-Cep152 heterotetrameric complex | | 分子名称: | Centrosomal protein of 63 kDa,Centrosomal protein of 152 kDa | | 著者 | Lee, E, Chen, Y, Zhang, L, Kim, T.S, Ahn, J.I, Park, J.E, Lee, K.S. | | 登録日 | 2018-03-21 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular architecture of a cylindrical self-assembly at human centrosomes.
Nat Commun, 10, 2019
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6CSU
 | | The structure of the Cep63-Cep152 heterotetrameric complex | | 分子名称: | Centrosomal protein of 152 kDa, Centrosomal protein of 63 kDa | | 著者 | Lee, E, Chen, Y, Zhang, L, Kim, T.S, Ahn, J.I, Park, J.E, Lee, K.S. | | 登録日 | 2018-03-21 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular architecture of a cylindrical self-assembly at human centrosomes.
Nat Commun, 10, 2019
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4O6W
 | | Peptide-Based Inhibitors of Plk1 Polo-box Domain | | 分子名称: | Peptide-Based inhibitor, Serine/threonine-protein kinase PLK1 | | 著者 | Qian, W.-J, Park, J.-E, Lim, D.C, Park, S.-Y, Lee, K.-W, Yaffe, M.B, Lee, K.S, Burke, T.R. | | 登録日 | 2013-12-23 | | 公開日 | 2014-12-03 | | 実験手法 | X-RAY DIFFRACTION (1.448 Å) | | 主引用文献 | Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in hela cells.
Biopolymers, 102, 2014
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5XE3
 | | Endoribonuclease in complex with its cognate antitoxin from Mycobacterial species | | 分子名称: | Endoribonuclease MazF4, Probable antitoxin MazE4 | | 著者 | Ahn, D.-H, Lee, K.-Y, Lee, S.J, Yoon, H.J, Kim, S.-J, Lee, B.-J. | | 登録日 | 2017-03-31 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural analyses of the MazEF4 toxin-antitoxin pair in Mycobacterium tuberculosis provide evidence for a unique extracellular death factor.
J. Biol. Chem., 292, 2017
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1JTD
 | | Crystal structure of beta-lactamase inhibitor protein-II in complex with TEM-1 beta-lactamase | | 分子名称: | CALCIUM ION, TEM-1 beta-lactamase, beta-lactamase inhibitor protein II | | 著者 | Lim, D.C, Park, H.U, De Castro, L, Kang, S.G, Lee, H.S, Jensen, S, Lee, K.J, Strynadka, N.C.J. | | 登録日 | 2001-08-20 | | 公開日 | 2001-10-03 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure and kinetic analysis of beta-lactamase inhibitor protein-II in complex with TEM-1 beta-lactamase.
Nat.Struct.Biol., 8, 2001
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4NQY
 | | The reduced form of MJ0499 | | 分子名称: | Isopropylmalate/citramalate isomerase large subunit, ZINC ION | | 著者 | Hwang, K.Y, Lee, E.H, Lee, K. | | 登録日 | 2013-11-26 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural characterization and comparison of the large subunits of IPM isomerase and homoaconitase from Methanococcus jannaschii
Acta Crystallogr.,Sect.D, 70, 2014
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6PTS
 | | NMR data-driven model of KRas-GMPPNP:RBD-CRD complex tethered to a nanodisc (state A) | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... | | 著者 | Fang, Z, Lee, K, Gasmi-Seabrook, G, Ikura, M, Marshall, C.B. | | 登録日 | 2019-07-16 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6PTW
 | | NMR data-driven model of KRas-GMPPNP:RBD-CRD complex tethered to a nanodisc (state B) | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... | | 著者 | Fang, Z, Lee, K, Gasmi-Seabrook, G, Ikura, M, Marshall, C.B. | | 登録日 | 2019-07-16 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane.
Proc.Natl.Acad.Sci.USA, 117, 2020
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4DWZ
 | | Crystal Structure of Ton_0340 | | 分子名称: | Hypothetical protein TON_0340, ZINC ION | | 著者 | Lee, S.G, Lee, K.H, Cha, S.S, Oh, B.H. | | 登録日 | 2012-02-27 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Experimental phasing using zinc anomalous scattering
Acta Crystallogr.,Sect.D, 68, 2012
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4FC5
 | | Crystal Structure of Ton_0340 | | 分子名称: | Putative uncharacterized protein, ZINC ION | | 著者 | Lee, S.G, Lee, K.H, An, Y.J, Cha, S.S, Oh, B.H. | | 登録日 | 2012-05-24 | | 公開日 | 2012-09-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Experimental phasing using zinc anomalous scattering
Acta Crystallogr.,Sect.D, 68, 2012
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4Q0F
 | | Crystal Structure of Thermotoga maritima FtsH Periplasmic domain | | 分子名称: | ATP-dependent zinc metalloprotease FtsH | | 著者 | An, J.Y, Sharif, H, Barrera, F.N, Karabadzhak, A, Kang, G.B, Park, K.J, Sakkiah, S, Lee, K.W, Lee, S, Engelman, D.M, Wang, J, Eom, S.H. | | 登録日 | 2014-04-01 | | 公開日 | 2015-04-01 | | 実験手法 | X-RAY DIFFRACTION (1.948 Å) | | 主引用文献 | Structures of periplasmic and transmembrane domains of FtsH suggest a reverse translocon mechanism for protein extraction from membrane
To be Published
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5XE2
 | | Endoribonuclease from Mycobacterial species | | 分子名称: | Endoribonuclease MazF4 | | 著者 | Ahn, D.-H, Lee, K.-Y, Lee, S.J, Yoon, H.J, Kim, S.-J, Lee, B.-J. | | 登録日 | 2017-03-31 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structural analyses of the MazEF4 toxin-antitoxin pair in Mycobacterium tuberculosis provide evidence for a unique extracellular death factor.
J. Biol. Chem., 292, 2017
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