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PDB: 222 件

5YOA
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Crystal structure of KAS III from Acinetobacter baumannii
分子名称: 3-Oxoacyl-[acyl-carrier-(ACP)] synthase III C terminal family protein, OCTANOYL-COENZYME A
著者Lee, W.C, Jung, M, Lee, J, Kim, Y.
登録日2017-10-27
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal structure of a novel KAS III from Acinetobacter baumannii
to be published
5YZU
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Crystal structure of KAS III from Acinetobacter baumannii
分子名称: 3-Oxoacyl-[acyl-carrier-(ACP)] synthase III C terminal family protein
著者Lee, W.C, Jung, M, Lee, J, Kim, Y.
登録日2017-12-15
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.122 Å)
主引用文献Crystal structure of a novel KAS III from Acinetobacter baumannii
to be published
2KI2
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Solution Structure of ss-DNA Binding Protein 12RNP2 Precursor, HP0827(O25501_HELPY) form Helicobacter pylori
分子名称: Ss-DNA binding protein 12RNP2
著者Ma, C, Lee, J, Kim, J, Park, S, Kwon, A, Lee, B.
登録日2009-04-20
公開日2009-10-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR solution structure of HP0827 (O25501_HELPY) from Helicobacter pylori: model of the possible RNA-binding site
J.Biochem., 146, 2009
1LX8
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Regulation of directionality in bacteriophage lambda site-specific recombination: structure of the Xis protein
分子名称: Excisionase
著者Sam, M.D, Papagiannis, C, Connolly, K.M, Corselli, L, Iwahara, J, Lee, J, Phillips, M, Wojciak, J.M, Johnson, R.C, Clubb, R.T.
登録日2002-06-04
公開日2003-06-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Regulation of directionality in bacteriophage lambda site-specific recombination: structure of the Xis protein
J.Mol.Biol., 324, 2002
8SXR
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Crystal structure of SARS-CoV-2 Mpro with C5a
分子名称: 3C-like proteinase nsp5, N-[(4-chlorothiophen-2-yl)methyl]-N-[4-(dimethylamino)phenyl]-2-(5-hydroxyisoquinolin-4-yl)acetamide
著者Worrall, L.J, Kenward, C, Lee, J, Strynadka, N.C.J.
登録日2023-05-23
公開日2023-08-30
実験手法X-RAY DIFFRACTION (2.114 Å)
主引用文献A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants.
Emerg Microbes Infect, 12, 2023
2KCC
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Solution Structure of biotinoyl domain from human acetyl-CoA carboxylase 2
分子名称: Acetyl-CoA carboxylase 2
著者Lee, C, Cheong, H, Ryu, K, Lee, J, Lee, W, Jeon, Y, Cheong, C.
登録日2008-12-19
公開日2009-02-17
最終更新日2023-09-27
実験手法SOLUTION NMR
主引用文献Biotinoyl domain of human acetyl-CoA carboxylase: Structural insights into the carboxyl transfer mechanism.
Proteins, 72, 2008
8CYU
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Crystal structure of SARS-CoV-2 Mpro with compound C5
分子名称: 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-N-[4-(dimethylamino)phenyl]-2-(isoquinolin-4-yl)acetamide
著者Worrall, L.J, Lee, J, Strynadka, N.C.J.
登録日2022-05-24
公開日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants.
Emerg Microbes Infect, 12, 2023
8CZ7
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Crystal structure of SARS-CoV-2 Mpro with compound C2
分子名称: 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)-N-(4-methoxyphenyl)acetamide
著者Worrall, L.J, Lee, J, Strynadka, N.C.J.
登録日2022-05-24
公開日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants.
Emerg Microbes Infect, 12, 2023
8CYZ
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Crystal structure of SARS-CoV-2 Mpro with compound C4
分子名称: 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)-N-[4-(methylsulfanyl)phenyl]acetamide
著者Worrall, L.J, Lee, J, Strynadka, N.C.J.
登録日2022-05-24
公開日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants.
Emerg Microbes Infect, 12, 2023
8CZ4
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Crystal structure of SARS-CoV-2 Mpro with compound C3
分子名称: 3C-like proteinase, N-(4-tert-butylphenyl)-N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)acetamide
著者Worrall, L.J, Lee, J, Strynadka, N.C.J.
登録日2022-05-24
公開日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants.
Emerg Microbes Infect, 12, 2023
3KPX
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Crystal Structure Analysis of photoprotein clytin
分子名称: Apophotoprotein clytin-3, C2-HYDROPEROXY-COELENTERAZINE, CALCIUM ION
著者Titushin, M.S, Li, Y, Stepanyuk, G.A, Wang, B.-C, Lee, J, Vysotski, E.S, Liu, Z.-J.
登録日2009-11-17
公開日2010-10-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.899 Å)
主引用文献NMR derived topology of a GFP-photoprotein energy transfer complex
J.Biol.Chem., 285, 2010
2CW0
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Crystal structure of Thermus thermophilus RNA polymerase holoenzyme at 3.3 angstroms resolution
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
著者Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark Jr, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E.
登録日2005-06-15
公開日2005-09-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation
Cell(Cambridge,Mass.), 122, 2005
2F0Y
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Crystal Structure Of Human Protein Farnesyltransferase Complexed With Farnesyl Diphosphate and hydantoin derivative
分子名称: 3-({3-[3-(1H-IMIDAZOL-1-YL)PROPYL]-5-METHYL-5-(1-NAPHTHYL)-2,4-DIOXOIMIDAZOLIDIN-1-YL}METHYL)BENZONITRILE, FARNESYL DIPHOSPHATE, Protein farnesyltransferase beta subunit, ...
著者Kim, K.H, Lee, J, Kim, J.
登録日2005-11-14
公開日2006-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献hydantoin derivatives as Non-pepridic inhibitors of Ras Farnesyl transferase
To be published
4PKX
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The structure of a conserved Piezo channel domain reveals a novel beta sandwich fold
分子名称: Protein C10C5.1, isoform i
著者Kamajaya, A, Kaiser, J, Lee, J, Reid, M, Rees, D.C.
登録日2014-05-15
公開日2014-10-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献The Structure of a Conserved Piezo Channel Domain Reveals a Topologically Distinct beta Sandwich Fold.
Structure, 22, 2014
2PNL
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Crystal structure of VP4 protease from infectious pancreatic necrosis virus (IPNV) in space group P1
分子名称: GUANIDINE, Protease VP4
著者Paetzel, M, Lee, J, Feldman, A.R, Delmas, B.
登録日2007-04-24
公開日2007-06-05
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction.
J.Biol.Chem., 282, 2007
4PKE
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The structure of a conserved Piezo channel domain reveals a novel beta sandwich fold
分子名称: PLATINUM (II) ION, Protein C10C5.1, isoform i
著者Kamajaya, A, Kaiser, J, Lee, J, Reid, M, Rees, D.C.
登録日2014-05-14
公開日2014-10-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Structure of a Conserved Piezo Channel Domain Reveals a Topologically Distinct beta Sandwich Fold.
Structure, 22, 2014
2PNM
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Crystal Structure of VP4 protease from infectious pancreatic necrosis virus (IPNV) in space group P6122
分子名称: Protease VP4
著者Paetzel, M, Lee, J, Feldman, A.R, Delmas, B.
登録日2007-04-24
公開日2007-06-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction.
J.Biol.Chem., 282, 2007
1ZYR
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BU of 1zyr by Molmil
Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic streptolydigin
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase omega chain, ...
著者Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E.
登録日2005-06-10
公開日2005-09-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation.
Cell(Cambridge,Mass.), 122, 2005
4FJS
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Crystal structure of ureidoglycolate dehydrogenase enzyme in apo form
分子名称: Ureidoglycolate dehydrogenase
著者Kim, M.I, Shin, I, Lee, J, Rhee, S.
登録日2012-06-12
公開日2013-01-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural and functional insights into (s)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization.
Plos One, 7, 2012
4MN0
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Spatial structure of the novel light-sensitive photoprotein berovin from the ctenophore Beroe abyssicola in the Ca2+-loaded apoprotein conformation state
分子名称: Berovin, CALCIUM ION, MAGNESIUM ION
著者Liu, Z.J, Stepanyuk, G.A, Vysotski, E.S, Lee, J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2013-09-09
公開日2013-10-16
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Spatial structure of the novel light-sensitive photoprotein berovin from the ctenophore Beroe abyssicola in the Ca(2+)-loaded apoprotein conformation state.
Biochim.Biophys.Acta, 1834, 2013
7LKP
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Structure of ATP-free human ABCA4
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Liu, F, Lee, J, Chen, J.
登録日2021-02-02
公開日2021-03-03
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Molecular structures of the eukaryotic retinal importer ABCA4.
Elife, 10, 2021
7LKZ
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Structure of ATP-bound human ABCA4
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Liu, F, Lee, J, Chen, J.
登録日2021-02-03
公開日2021-03-03
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Molecular structures of the eukaryotic retinal importer ABCA4.
Elife, 10, 2021
4N1G
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Crystal Structure of Ca(2+)- discharged F88Y obelin mutant from Obelia longissima at 1.50 Angstrom resolution
分子名称: CALCIUM ION, N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE, Obelin
著者Natashin, P.V, Markova, S.V, Lee, J, Vysotski, E.S, Liu, Z.J.
登録日2013-10-04
公開日2014-02-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structures of the F88Y obelin mutant before and after bioluminescence provide molecular insight into spectral tuning among hydromedusan photoproteins
Febs J., 281, 2014
3BA5
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Crystal structure of D28A mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Blaber, M, Lee, J.
登録日2007-11-07
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BAD
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Crystal structure of D70A/H93G mutant of Human acidic fibroblast growth factor
分子名称: Heparin-binding growth factor 1, SULFATE ION
著者Blaber, M, Lee, J.
登録日2007-11-07
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008

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