1NC1
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![BU of 1nc1 by Molmil](/molmil-images/mine/1nc1) | Crystal structure of E. coli MTA/AdoHcy nucleosidase complexed with 5'-methylthiotubercidin (MTH) | 分子名称: | 2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-METHYLSULFANYLMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, MTA/SAH nucleosidase | 著者 | Lee, J.E, Cornell, K.A, Riscoe, M.K, Howell, P.L. | 登録日 | 2002-12-04 | 公開日 | 2003-11-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of Escherichia coli 5'-methylthioadenosine/ S-adenosylhomocysteine nucleosidase inhibitor complexes provide insight into the conformational changes required for substrate binding and catalysis. J.Biol.Chem., 278, 2003
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1NC3
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![BU of 1nc3 by Molmil](/molmil-images/mine/1nc3) | Crystal structure of E. coli MTA/AdoHcy nucleosidase complexed with formycin A (FMA) | 分子名称: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, MTA/SAH nucleosidase | 著者 | Lee, J.E, Cornell, K.A, Riscoe, M.K, Howell, P.L. | 登録日 | 2002-12-04 | 公開日 | 2003-03-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of Escherichia coli 5'-methylthioadenosine/ S-adenosylhomocysteine nucleosidase inhibitor complexes provide insight into the conformational changes required for substrate binding and catalysis. J.Biol.Chem., 278, 2003
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3INU
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![BU of 3inu by Molmil](/molmil-images/mine/3inu) | Crystal structure of an unbound KZ52 neutralizing anti-Ebolavirus antibody. | 分子名称: | GLYCEROL, KZ52 antibody fragment heavy chain, KZ52 antibody fragment light chain, ... | 著者 | Lee, J.E, Fusco, M.L, Abelson, D.M, Hessell, A.J, Burton, D.R, Saphire, E.O. | 登録日 | 2009-08-12 | 公開日 | 2009-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Techniques and tactics used in determining the structure of the trimeric ebolavirus glycoprotein. Acta Crystallogr.,Sect.D, 65, 2009
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1Y6Q
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![BU of 1y6q by Molmil](/molmil-images/mine/1y6q) | Cyrstal structure of MTA/AdoHcy nucleosidase complexed with MT-DADMe-ImmA | 分子名称: | (3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL, CHLORIDE ION, MTA/SAH nucleosidase | 著者 | Lee, J.E, Singh, V, Evans, G.B, Tyler, P.C, Furneaux, R.H, Cornell, K.A, Riscoe, M.K, Schramm, V.L, Howell, P.L. | 登録日 | 2004-12-06 | 公開日 | 2005-03-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. J.Biol.Chem., 280, 2005
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1Y6R
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![BU of 1y6r by Molmil](/molmil-images/mine/1y6r) | Crystal structure of MTA/AdoHcy nucleosidase complexed with MT-ImmA. | 分子名称: | (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL, MTA/SAH nucleosidase | 著者 | Lee, J.E, Singh, V, Evans, G.B, Tyler, P.C, Furneaux, R.H, Cornell, K.A, Riscoe, M.K, Schramm, V.L, Howell, P.L. | 登録日 | 2004-12-06 | 公開日 | 2005-03-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. J.Biol.Chem., 280, 2005
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1SD1
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![BU of 1sd1 by Molmil](/molmil-images/mine/1sd1) | STRUCTURE OF HUMAN 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH FORMYCIN A | 分子名称: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, 5'-methylthioadenosine phosphorylase | 著者 | Lee, J.E, Settembre, E.C, Cornell, K.A, Riscoe, M.K, Sufrin, J.R, Ealick, S.E, Howell, P.L. | 登録日 | 2004-02-12 | 公開日 | 2004-05-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structural Comparison of MTA Phosphorylase and MTA/AdoHcy Nucleosidase Explains Substrate Preferences and Identifies Regions Exploitable for Inhibitor Design. Biochemistry, 43, 2004
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1SD2
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![BU of 1sd2 by Molmil](/molmil-images/mine/1sd2) | STRUCTURE OF HUMAN 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH 5'-METHYLTHIOTUBERCIDIN | 分子名称: | 2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-METHYLSULFANYLMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, 5'-methylthioadenosine phosphorylase, SULFATE ION | 著者 | Lee, J.E, Settembre, E.C, Cornell, K.A, Riscoe, M.K, Sufrin, J.R, Ealick, S.E, Howell, P.L. | 登録日 | 2004-02-12 | 公開日 | 2004-05-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Comparison of MTA Phosphorylase and MTA/AdoHcy Nucleosidase Explains Substrate Preferences and Identifies Regions Exploitable for Inhibitor Design. Biochemistry, 43, 2004
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3CSY
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![BU of 3csy by Molmil](/molmil-images/mine/3csy) | Crystal structure of the trimeric prefusion Ebola virus glycoprotein in complex with a neutralizing antibody from a human survivor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein GP1, ... | 著者 | Lee, J.E, Fusco, M.L, Hessell, A.J, Oswald, W.B, Burton, D.R, Saphire, E.O. | 登録日 | 2008-04-10 | 公開日 | 2008-07-08 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor. Nature, 454, 2008
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1JYS
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![BU of 1jys by Molmil](/molmil-images/mine/1jys) | Crystal Structure of E. coli MTA/AdoHcy Nucleosidase | 分子名称: | ADENINE, MTA/SAH nucleosidase | 著者 | Lee, J.E, Cornell, K.A, Riscoe, M.K, Howell, P.L. | 登録日 | 2001-09-13 | 公開日 | 2002-10-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of E. coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase reveals similarity to the purine nucleoside phosphorylases. Structure, 9, 2001
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1Z5P
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![BU of 1z5p by Molmil](/molmil-images/mine/1z5p) | Crystal structure of MTA/AdoHcy nucleosidase with a ligand-free purine binding site | 分子名称: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, GLYCEROL, ISOPROPYL ALCOHOL, ... | 著者 | Lee, J.E, Smith, G.D, Horvatin, C, Huang, D.J.T, Cornell, K.A, Riscoe, M.K, Howell, P.L. | 登録日 | 2005-03-18 | 公開日 | 2005-10-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis J.Mol.Biol., 352, 2005
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1Z5O
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![BU of 1z5o by Molmil](/molmil-images/mine/1z5o) | Crystal structure of MTA/AdoHcy nucleosidase Asp197Asn mutant complexed with 5'-methylthioadenosine | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, MTA/SAH nucleosidase | 著者 | Lee, J.E, Smith, G.D, Horvatin, C, Huang, D.J.T, Cornell, K.A, Riscoe, M.K, Howell, P.L. | 登録日 | 2005-03-18 | 公開日 | 2005-10-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis J.Mol.Biol., 352, 2005
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1Z5N
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![BU of 1z5n by Molmil](/molmil-images/mine/1z5n) | Crystal structure of MTA/AdoHcy nucleosidase Glu12Gln mutant complexed with 5-methylthioribose and adenine | 分子名称: | 5-S-methyl-5-thio-alpha-D-ribofuranose, ADENINE, MTA/SAH nucleosidase | 著者 | Lee, J.E, Smith, G.D, Horvatin, C, Huang, D.J.T, Cornell, K.A, Riscoe, M.K, Howell, P.L. | 登録日 | 2005-03-18 | 公開日 | 2005-10-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis J.Mol.Biol., 352, 2005
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2QHR
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![BU of 2qhr by Molmil](/molmil-images/mine/2qhr) | Crystal structure of the 13F6-1-2 Fab fragment bound to its Ebola virus glycoprotein peptide epitope. | 分子名称: | 13F6-1-2 Fab fragment V lambda x light chain, 13F6-1-2 Fab fragment heavy chain, Envelope glycoprotein peptide | 著者 | Lee, J.E, Kuehne, A, Abelson, D.M, Fusco, M.L, Hart, M.K, Saphire, E.O. | 登録日 | 2007-07-02 | 公開日 | 2008-01-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Complex of a protective antibody with its Ebola virus GP peptide epitope: unusual features of a V lambda x light chain. J.Mol.Biol., 375, 2008
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7S94
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![BU of 7s94 by Molmil](/molmil-images/mine/7s94) | |
7N07
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![BU of 7n07 by Molmil](/molmil-images/mine/7n07) | Crystal structure of the apo 3D6 antibody fragment | 分子名称: | Fab 3D6 heavy chain, Fab 3D6 light chain, SULFATE ION | 著者 | Cook, J.D, Lee, J.E. | 登録日 | 2021-05-25 | 公開日 | 2022-03-30 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Conformational plasticity of the HIV-1 gp41 immunodominant region is recognized by multiple non-neutralizing antibodies. Commun Biol, 5, 2022
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7N04
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![BU of 7n04 by Molmil](/molmil-images/mine/7n04) | Crystal structure of the apo F240 antibody fragment | 分子名称: | Fab F240 heavy chain, Fab F240 light chain, alpha-D-glucopyranose | 著者 | Cook, J.D, Lee, J.E. | 登録日 | 2021-05-25 | 公開日 | 2022-03-30 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.70000517 Å) | 主引用文献 | Conformational plasticity of the HIV-1 gp41 immunodominant region is recognized by multiple non-neutralizing antibodies. Commun Biol, 5, 2022
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7N08
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![BU of 7n08 by Molmil](/molmil-images/mine/7n08) | |
7N05
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![BU of 7n05 by Molmil](/molmil-images/mine/7n05) | |
7TA2
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![BU of 7ta2 by Molmil](/molmil-images/mine/7ta2) | Crystal structure of the human sperm-expressed surface protein SPACA6 | 分子名称: | BROMIDE ION, Sperm acrosome membrane-associated protein 6 | 著者 | Vance, T.D.R, Yip, P, Jimenez, E, Uson, I, Lee, J.E. | 登録日 | 2021-12-20 | 公開日 | 2022-08-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | SPACA6 ectodomain structure reveals a conserved superfamily of gamete fusion-associated proteins. Commun Biol, 5, 2022
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7UJV
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![BU of 7ujv by Molmil](/molmil-images/mine/7ujv) | Structure of PHD2 in complex with HIF2a-CODD | 分子名称: | Egl nine homolog 1, Endothelial PAS domain-containing protein 1, FE (III) ION, ... | 著者 | Ferens, F.G, Tarade, D, Lee, J.E, Ohh, M. | 登録日 | 2022-03-31 | 公開日 | 2023-04-05 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Deficiency in PHD2-mediated hydroxylation of HIF2 alpha underlies Pacak-Zhuang syndrome. Commun Biol, 7, 2024
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4XYP
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![BU of 4xyp by Molmil](/molmil-images/mine/4xyp) | Crystal structure of a piscine viral fusion protein | 分子名称: | 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM, CHLORIDE ION, Fusion protein | 著者 | Cook, J.D, Lee, J.E. | 登録日 | 2015-02-02 | 公開日 | 2015-06-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Electrostatic Architecture of the Infectious Salmon Anemia Virus (ISAV) Core Fusion Protein Illustrates a Carboxyl-Carboxylate pH Sensor. J.Biol.Chem., 290, 2015
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2Y6S
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![BU of 2y6s by Molmil](/molmil-images/mine/2y6s) | Structure of an Ebolavirus-protective antibody in complex with its mucin-domain linear epitope | 分子名称: | ENVELOPE GLYCOPROTEIN, HEAVY CHAIN, LIGHT CHAIN | 著者 | Olal, D.O, Kuehne, A, Lee, J.E, Bale, S, Dye, J.M, Saphire, E.O. | 登録日 | 2011-01-25 | 公開日 | 2012-01-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of an Ebola Virus-Protective Antibody in Complex with its Mucin-Domain Linear Epitope. J.Virol., 86, 2012
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3BL6
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![BU of 3bl6 by Molmil](/molmil-images/mine/3bl6) | Crystal structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase in complex with formycin A | 分子名称: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase | 著者 | Siu, K.K.W, Lee, J.E, Smith, G.D, Horvatin, C, Howell, P.L. | 登録日 | 2007-12-10 | 公開日 | 2008-06-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Acta Crystallogr.,Sect.F, 64, 2008
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1JDI
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![BU of 1jdi by Molmil](/molmil-images/mine/1jdi) | CRYSTAL STRUCTURE OF L-RIBULOSE-5-PHOSPHATE 4-EPIMERASE | 分子名称: | L-RIBULOSE 5 PHOSPHATE 4-EPIMERASE, ZINC ION | 著者 | Luo, Y, Samuel, J, Mosimann, S.C, Lee, J.E, Tanner, M.E, Strynadka, N.C.J. | 登録日 | 2001-06-13 | 公開日 | 2002-01-23 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The structure of L-ribulose-5-phosphate 4-epimerase: an aldolase-like platform for epimerization. Biochemistry, 40, 2001
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6WKO
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![BU of 6wko by Molmil](/molmil-images/mine/6wko) | |