1Y6R

Crystal structure of MTA/AdoHcy nucleosidase complexed with MT-ImmA.

Summary for 1Y6R

Entry DOI	10.2210/pdb1y6r/pdb
Related	1Y6Q
Descriptor	MTA/SAH nucleosidase, (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL (3 entities in total)
Functional Keywords	mixed alpha/beta, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	51571.00
Authors	Lee, J.E.,Singh, V.,Evans, G.B.,Tyler, P.C.,Furneaux, R.H.,Cornell, K.A.,Riscoe, M.K.,Schramm, V.L.,Howell, P.L. (deposition date: 2004-12-06, release date: 2005-03-01, Last modification date: 2023-08-23)
Primary citation	Lee, J.E.,Singh, V.,Evans, G.B.,Tyler, P.C.,Furneaux, R.H.,Cornell, K.A.,Riscoe, M.K.,Schramm, V.L.,Howell, P.L. Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. J.Biol.Chem., 280:18274-18282, 2005 Cited by PubMed: 15746096 DOI: 10.1074/jbc.M414471200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation