3QWZ
 
 | | Crystal structure of FAF1 UBX-p97N-domain complex | | 分子名称: | FAS-associated factor 1, Transitional endoplasmic reticulum ATPase | | 著者 | Park, J.K, Jeon, H, Lee, J.J, Kim, K.H, Lee, K.J, Kim, E.E. | | 登録日 | 2011-02-28 | | 公開日 | 2012-05-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Dissection of the interaction between FAF1 UBX and p97
To be Published
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1J9K
 | | CRYSTAL STRUCTURE OF SURE PROTEIN FROM T.MARITIMA IN COMPLEX WITH TUNGSTATE | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, STATIONARY PHASE SURVIVAL PROTEIN, ... | | 著者 | Suh, S.W, Lee, J.Y, Kwak, J.E, Moon, J. | | 登録日 | 2001-05-27 | | 公開日 | 2001-09-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure and functional analysis of the SurE protein identify a novel phosphatase family.
Nat.Struct.Biol., 8, 2001
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2KI2
 | | Solution Structure of ss-DNA Binding Protein 12RNP2 Precursor, HP0827(O25501_HELPY) form Helicobacter pylori | | 分子名称: | Ss-DNA binding protein 12RNP2 | | 著者 | Ma, C, Lee, J, Kim, J, Park, S, Kwon, A, Lee, B. | | 登録日 | 2009-04-20 | | 公開日 | 2009-10-20 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structure of HP0827 (O25501_HELPY) from Helicobacter pylori: model of the possible RNA-binding site
J.Biochem., 146, 2009
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5WLY
 | | E. coli LpxH- 8 mutations | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, FORMIC ACID, ... | | 著者 | Bohl, T.E, Aihara, H, Shi, K, Lee, J.K. | | 登録日 | 2017-07-28 | | 公開日 | 2018-04-11 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The substrate-binding cap of the UDP-diacylglucosamine pyrophosphatase LpxH is highly flexible, enabling facile substrate binding and product release.
J. Biol. Chem., 293, 2018
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7WV4
 | | ectoTLR3-poly(I:C) cluster | | 分子名称: | RNA (80-MER), Toll-like receptor 3 | | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | 登録日 | 2022-02-09 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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7WVF
 | | ectoTLR3-mAb12-poly(I:C) complex | | 分子名称: | RNA (46-MER), Toll-like receptor 3, mAb12 | | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | 登録日 | 2022-02-10 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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7WVJ
 | | NT-mut(K117D,K139D,K145D) TLR3 -poly I:C complex | | 分子名称: | RNA (46-MER), Toll-like receptor 3 | | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | 登録日 | 2022-02-10 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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7WVE
 | | CT-mut (D523K,D524K,E527K) TLR3-poly(I:C) complex | | 分子名称: | RNA (46-MER), Toll-like receptor 3 | | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | 登録日 | 2022-02-10 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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4ERZ
 | | X-ray structure of WDR5-MLL4 Win motif peptide binary complex | | 分子名称: | Histone-lysine N-methyltransferase MLL4, WD repeat-containing protein 5 | | 著者 | Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S. | | 登録日 | 2012-04-21 | | 公開日 | 2012-05-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287, 2012
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5F3K
 | | X-Ray Crystallographic Structure of hTrap1 N-terminal Domain-apo | | 分子名称: | Heat shock protein 75 kDa, mitochondrial | | 著者 | Sung, N, Lee, J, Kim, J, Chang, C, Joachimiak, A, Lee, S, Tsai, F.T.F. | | 登録日 | 2015-12-02 | | 公開日 | 2016-03-02 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP binding to dimer closure through a coiled-coil intermediate.
Proc.Natl.Acad.Sci.USA, 113, 2016
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6V05
 | | Cryo-EM structure of a substrate-engaged Bam complex | | 分子名称: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamA,Outer membrane protein assembly factor BamA,Outer membrane protein assembly factor BamA,Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | | 著者 | Tomasek, D, Rawson, S, Lee, J, Wzorek, J.S, Harrison, S.C, Li, Z, Kahne, D. | | 登録日 | 2019-11-18 | | 公開日 | 2020-06-10 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structure of a nascent membrane protein as it folds on the BAM complex.
Nature, 583, 2020
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7DVN
 | | Crystal structure of a MarR family protein in complex with a lipid-like effector molecule from the psychrophilic bacterium Paenisporosarcina sp. TG-14 | | 分子名称: | MarR family transcriptional regulator, PALMITIC ACID | | 著者 | Lee, C.W, Hwang, J, Do, H, Lee, J.H. | | 登録日 | 2021-01-14 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of a MarR family protein from the psychrophilic bacterium Paenisporosarcina sp. TG-14 in complex with a lipid-like molecule.
Iucrj, 8, 2021
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6D2L
 | | Crystal structure of human CARM1 with (S)-SKI-72 | | 分子名称: | (2S,5S)-2-amino-6-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-5-[(benzylamino)methyl]-N-[2-(4-hydroxyphenyl)ethyl]hexanamide, GLYCEROL, Histone-arginine methyltransferase CARM1, ... | | 著者 | DONG, A, ZENG, H, WALKER, J.R, Hutchinson, A, Seitova, A, LUO, M, CAI, X.C, KE, W, WANG, J, SHI, C, ZHENG, W, LEE, J.P, IBANEZ, G, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC) | | 登録日 | 2018-04-13 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion.
Elife, 8, 2019
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2O4C
 | | Crystal Structure of D-Erythronate-4-phosphate Dehydrogenase Complexed with NAD | | 分子名称: | Erythronate-4-phosphate dehydrogenase, GLYCEROL, L(+)-TARTARIC ACID, ... | | 著者 | Ha, J.Y, Lee, J.H, Kim, K.H, Kim, D.J, Lee, H.H, Kim, H.K, Yoon, H.J, Suh, S.W. | | 登録日 | 2006-12-04 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of d-Erythronate-4-phosphate Dehydrogenase Complexed with NAD
J.Mol.Biol., 366, 2007
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6ILA
 | | Two Glycerol complexed Crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi | | 分子名称: | Fructuronate-tagaturonate epimerase UxaE, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Choi, M.Y, Kang, L.W, Ho, T.H, Nguyen, D.Q, Lee, I.H, Lee, J.H, Park, Y.S, Park, H.J. | | 登録日 | 2018-10-17 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi
To be published
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6IL9
 | | One Glycerol complexed Crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi | | 分子名称: | Fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi in complex with 1 glycerol, GLYCEROL, ZINC ION | | 著者 | Choi, M.Y, Kang, L.W, Ho, T.H, Nguyen, D.Q, Lee, I.H, Lee, J.H, Park, Y.S, Park, H.J. | | 登録日 | 2018-10-17 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.72005355 Å) | | 主引用文献 | Crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi
To Be Published
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8CZ4
 | | Crystal structure of SARS-CoV-2 Mpro with compound C3 | | 分子名称: | 3C-like proteinase, N-(4-tert-butylphenyl)-N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)acetamide | | 著者 | Worrall, L.J, Lee, J, Strynadka, N.C.J. | | 登録日 | 2022-05-24 | | 公開日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants.
Emerg Microbes Infect, 12, 2023
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8CYU
 | | Crystal structure of SARS-CoV-2 Mpro with compound C5 | | 分子名称: | 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-N-[4-(dimethylamino)phenyl]-2-(isoquinolin-4-yl)acetamide | | 著者 | Worrall, L.J, Lee, J, Strynadka, N.C.J. | | 登録日 | 2022-05-24 | | 公開日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants.
Emerg Microbes Infect, 12, 2023
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8CYZ
 | | Crystal structure of SARS-CoV-2 Mpro with compound C4 | | 分子名称: | 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)-N-[4-(methylsulfanyl)phenyl]acetamide | | 著者 | Worrall, L.J, Lee, J, Strynadka, N.C.J. | | 登録日 | 2022-05-24 | | 公開日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants.
Emerg Microbes Infect, 12, 2023
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8CZ7
 | | Crystal structure of SARS-CoV-2 Mpro with compound C2 | | 分子名称: | 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)-N-(4-methoxyphenyl)acetamide | | 著者 | Worrall, L.J, Lee, J, Strynadka, N.C.J. | | 登録日 | 2022-05-24 | | 公開日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants.
Emerg Microbes Infect, 12, 2023
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2JEL
 | | JEL42 FAB/HPR COMPLEX | | 分子名称: | HISTIDINE-CONTAINING PROTEIN, JEL42 FAB FRAGMENT, SULFATE ION | | 著者 | Prasad, L, Waygood, E.B, Lee, J.S, Delbaere, L.T.J. | | 登録日 | 1998-02-24 | | 公開日 | 1998-05-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The 2.5 A resolution structure of the jel42 Fab fragment/HPr complex
J.Mol.Biol., 280, 1998
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6ILB
 | | Native crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi | | 分子名称: | 1,2-ETHANEDIOL, Fructuronate-tagaturonate epimerase UxaE, MANGANESE (II) ION | | 著者 | Choi, M.Y, Kang, L.W, Ho, T.H, Nguyen, D.Q, Lee, I.H, Lee, J.H, Park, Y.S, Park, H.J. | | 登録日 | 2018-10-17 | | 公開日 | 2019-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi
To be published
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3JTR
 | | Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis | | 分子名称: | GLYCEROL, Glutaryl 7-aminocephalosporanic acid acylase | | 著者 | Cho, K.J, Kim, J.K, Lee, J.H, Shin, H.J, Park, S.S, Kim, K.H. | | 登録日 | 2009-09-14 | | 公開日 | 2010-01-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural features of cephalosporin acylase reveal the basis of autocatalytic activation.
Biochem.Biophys.Res.Commun., 390, 2009
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3JTQ
 | | Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis | | 分子名称: | GLYCEROL, Glutaryl 7-aminocephalosporanic acid acylase | | 著者 | Cho, K.J, Kim, J.K, Lee, J.H, Shin, H.J, Park, S.S, Kim, K.H. | | 登録日 | 2009-09-14 | | 公開日 | 2010-01-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural features of cephalosporin acylase reveal the basis of autocatalytic activation.
Biochem.Biophys.Res.Commun., 390, 2009
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7WI1
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