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PDB: 223 件

5IEC
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Structural basis for therapeutic inhibition of complement C5
分子名称: RaCI2
著者Sheppard, D, Lea, S.M.
登録日2016-02-25
公開日2016-04-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis for therapeutic inhibition of complement C5.
Nat.Struct.Mol.Biol., 23, 2016
5LHX
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BU of 5lhx by Molmil
PB3 Domain of Drosophila melanogaster PLK4 (Sak)
分子名称: Serine/threonine-protein kinase PLK4
著者Cottee, M.A, Lea, S.M.
登録日2016-07-13
公開日2017-03-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies.
Biol Open, 6, 2017
5LHY
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PB3 Domain of Human PLK4 (apo)
分子名称: Serine/threonine-protein kinase PLK4
著者Cottee, M.A, Johnson, S, Lea, S.M.
登録日2016-07-13
公開日2017-03-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies.
Biol Open, 6, 2017
5LHZ
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PB3 Domain of Human PLK4 in Complex with Coiled-Coil Domain of STIL
分子名称: SCL-interrupting locus protein, Serine/threonine-protein kinase PLK4
著者Cottee, M.A, Lea, S.M.
登録日2016-07-13
公開日2017-03-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies.
Biol Open, 6, 2017
5LHW
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BU of 5lhw by Molmil
Central Coiled-Coil Domain of Human STIL
分子名称: HEXAETHYLENE GLYCOL, SCL-interrupting locus protein
著者Cottee, M.A, Lea, S.M.
登録日2016-07-13
公開日2017-03-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (0.91 Å)
主引用文献A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies.
Biol Open, 6, 2017
1RXL
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BU of 1rxl by Molmil
Solution structure of the engineered protein Afae-dsc
分子名称: Afimbrial adhesin AFA-III
著者Anderson, K.L, Billington, J, Pettigrew, D, Cota, E, Roversi, P, Simpson, P, Chen, H.A, Urvil, P, du Merle, L, Barlow, P.N, Medof, M.E, Smith, R.A, Nowicki, B, Le Bouguenec, C, Lea, S.M, Matthews, S.
登録日2003-12-18
公開日2005-01-11
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献An atomic resolution model for assembly, architecture, and function of the Dr adhesins.
Mol.Cell, 15, 2004
3ZWU
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BU of 3zwu by Molmil
Pseudomonas fluorescens PhoX in complex with vanadate, a transition state analogue
分子名称: ALKALINE PHOSPHATASE PHOX, CALCIUM ION, CHLORIDE ION, ...
著者Yong, S.C, Roversi, P, Lillington, J.E.D, Zeldin, O.B, Garman, E.F, Lea, S.M, Berks, B.C.
登録日2011-08-02
公開日2012-08-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献A Complex Iron-Calcium Cofactor Catalyzing Phosphotransfer Chemistry
Science, 345, 2014
3ZD2
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BU of 3zd2 by Molmil
THE STRUCTURE OF THE TWO N-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 1 SHOWS FORMATION OF A NOVEL DIMERISATION INTERFACE
分子名称: 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 1
著者Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M.
登録日2012-11-23
公開日2013-03-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo.
Proc.Natl.Acad.Sci.USA, 110, 2013
3ZD1
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BU of 3zd1 by Molmil
STRUCTURE OF THE TWO C-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 2
分子名称: 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 2
著者Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M.
登録日2012-11-23
公開日2013-03-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo.
Proc.Natl.Acad.Sci.USA, 110, 2013
4AQB
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BU of 4aqb by Molmil
MBL-Ficolin Associated Protein-1, MAP-1 aka MAP44
分子名称: CALCIUM ION, MANNAN-BINDING LECTIN SERINE PROTEASE 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Skjoedt, M.O, Roversi, P, Hummelshoj, T, Palarasah, Y, Johnson, S, Lea, S.M, Garred, P.
登録日2012-04-16
公開日2012-08-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Crystal Structure and Functional Characterization of the Complement Regulator Mannose-Binding Lectin (Mbl)/Ficolin-Associated Protein-1 (Map-1).
J.Biol.Chem., 287, 2012
4A5W
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BU of 4a5w by Molmil
Crystal structure of C5b6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C5, ...
著者Hadders, M.A, Bubeck, D, Forneris, F, Pangburn, M, Llorca, O, Lea, S.M, Gros, P.
登録日2011-10-28
公開日2012-03-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9.
Cell Rep., 1, 2012
4A9V
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BU of 4a9v by Molmil
Pseudomonas fluorescens PhoX
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Yong, S.C, Roversi, P, Lillington, J.E.D, Zeldin, O.B, Garman, E.F, Lea, S.M, Berks, B.C.
登録日2011-11-28
公開日2012-12-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献A Complex Iron-Calcium Cofactor Catalyzing Phosphotransfer Chemistry
Science, 345, 2014
4AMF
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BU of 4amf by Molmil
Pseudomonas fluorescens PhoX in complex with the substrate analogue AppCp
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Yong, S.C, Roversi, P, Lillington, J.E.D, Zeldin, O.B, Garman, E.F, Lea, S.M, Berks, B.C.
登録日2012-03-09
公開日2013-03-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献A Complex Iron-Calcium Cofactor Catalyzing Phosphotransfer Chemistry
Science, 345, 2014
4ALF
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BU of 4alf by Molmil
Pseudomonas fluorescens PhoX in complex with phosphate
分子名称: 1,2-ETHANEDIOL, ALKALINE PHOSPHATASE PHOX, CALCIUM ION, ...
著者Yong, S.C, Roversi, P, Lillington, J.E.D, Zeldin, O.B, Garman, E.F, Lea, S.M, Berks, B.C.
登録日2012-03-02
公開日2013-03-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献A Complex Iron-Calcium Cofactor Catalyzing Phosphotransfer Chemistry
Science, 345, 2014
2J8B
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BU of 2j8b by Molmil
High resolution structure of human CD59
分子名称: CD59 GLYCOPROTEIN
著者Leath, K.J, Johnson, S, Roversi, P, Morgan, B.P, Smith, R.A.G, Lea, S.M.
登録日2006-10-24
公開日2007-08-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献High-Resolution Structures of Bacterially Expressed Soluble Human Cd59.
Acta Crystallogr.,Sect.F, 63, 2007
2JAA
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BU of 2jaa by Molmil
SeMet substituted Shigella Flexneri Ipad
分子名称: INVASIN IPAD
著者Johnson, S, Roversi, P, Espina, M, Olive, A, Deane, J.E, Birket, S, Field, T, Picking, W.D, Blocker, A.J, Galyov, E.E, Picking, W.L, Lea, S.M.
登録日2006-11-24
公開日2006-11-30
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Self-Chaperoning of the Type III Secretion System Needle Tip Proteins Ipad and Bipd.
J.Biol.Chem., 282, 2007
2JKL
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BU of 2jkl by Molmil
DraE Adhesin in complex with Bromamphenicol
分子名称: 1,2-ETHANEDIOL, BROMAMPHENICOL, CHLORAMPHENICOL, ...
著者Pettigrew, D.M, Roversi, P, Davies, S.G, Russell, A.J, Lea, S.M.
登録日2008-08-28
公開日2008-12-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Structural Study of the Interaction between the Dr Haemagglutinin Drae and Derivatives of Chloramphenicol
Acta Crystallogr.,Sect.D, 65, 2009
2JKJ
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BU of 2jkj by Molmil
DraE Adhesin in complex with Chloramphenicol Succinate
分子名称: CHLORAMPHENICOL, DR HEMAGGLUTININ STRUCTURAL SUBUNIT, SULFATE ION, ...
著者Pettigrew, D.M, Roversi, P, Davies, S.G, Russell, A.J, Lea, S.M.
登録日2008-08-28
公開日2008-12-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Structural Study of the Interaction between the Dr Haemagglutinin Drae and Derivatives of Chloramphenicol
Acta Crystallogr.,Sect.D, 65, 2009
2JKN
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BU of 2jkn by Molmil
DraE Adhesin in complex with Chloramphenicol Succinate (trigonal form)
分子名称: 1,2-ETHANEDIOL, CHLORAMPHENICOL SUCCINATE, DR HEMAGGLUTININ STRUCTURAL SUBUNIT, ...
著者Pettigrew, D.M, Roversi, P, Davies, S.G, Russell, A.J, Lea, S.M.
登録日2008-08-28
公開日2008-12-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A structural study of the interaction between the Dr haemagglutinin DraE and derivatives of chloramphenicol.
Acta Crystallogr. D Biol. Crystallogr., 65, 2009
5MWE
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BU of 5mwe by Molmil
Complex between the Leucine Zipper (LZ, residues 490-567) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn)
分子名称: 1,2-ETHANEDIOL, 3,3',3''-phosphanetriyltripropanoic acid, Centrosomin, ...
著者Feng, Z, Johnson, S, Raff, J.W, Lea, S.M.
登録日2017-01-18
公開日2017-06-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
5MW9
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BU of 5mw9 by Molmil
Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) - L535E mutant form
分子名称: Centrosomin, ZINC ION
著者Feng, Z, Johnson, S, Raff, J.W, Lea, S.M.
登録日2017-01-18
公開日2017-06-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
4TT9
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BU of 4tt9 by Molmil
Structure of the C-terminal SpoA domain of Shigella flexneri Spa33
分子名称: 1,2-ETHANEDIOL, Surface presentation of antigens protein SpaO
著者McDowell, M.A, Johnson, S, Lea, S.M.
登録日2014-06-20
公開日2015-06-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Characterisation of Shigella Spa33 and Thermotoga FliM/N reveals a new model for C-ring assembly in T3SS.
Mol.Microbiol., 99, 2016
5MVW
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BU of 5mvw by Molmil
Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Centrosomin, ...
著者Feng, Z, Johnson, S, Raff, J.W, Lea, S.M.
登録日2017-01-17
公開日2017-06-28
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
5MW0
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BU of 5mw0 by Molmil
Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) - L535E mutant form
分子名称: Centrosomin, ZINC ION
著者Feng, Z, Johnson, S, Raff, J.W, Lea, S.M.
登録日2017-01-17
公開日2017-06-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
5MWF
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BU of 5mwf by Molmil
Human Jagged2 C2-EGF2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Suckling, R.J, Handford, P.A, Lea, S.M.
登録日2017-01-18
公開日2017-06-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017

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