5IEC

Structural basis for therapeutic inhibition of complement C5

Summary for 5IEC

• Entry DOI: 10.2210/pdb5iec/pdb
• NMR Information: BMRB: 30024
• Descriptor: RaCI2 (1 entity in total)
• Functional Keywords: complement inhibitor, raci, structure from cyana 3.96, blood clotting
• Biological source: Rhipicephalus appendiculatus
• Total number of polymer chains: 1
• Total formula weight: 7476.49

Authors

Sheppard, D.,Lea, S.M. (deposition date: 2016-02-25, release date: 2016-04-27, Last modification date: 2023-06-14)

• Primary citation: Jore, M.M.,Johnson, S.,Sheppard, D.,Barber, N.M.,Li, Y.I.,Nunn, M.A.,Elmlund, H.,Lea, S.M.; Structural basis for therapeutic inhibition of complement C5.; Nat.Struct.Mol.Biol., 23:378-386, 2016; PubMed: 27018802; DOI: 10.1038/nsmb.3196

Experimental method

SOLUTION NMR