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PDB: 227 件
2W80
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Structure of a complex between Neisseria meningitidis factor H binding protein and CCPs 6-7 of human complement factor H
分子名称: COMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN
著者Schneider, M.C, Prosser, B.E, Caesar, J.J.E, Kugelberg, E, Li, S, Zhang, Q, Quoraishi, S, Lovett, J.E, Deane, J.E, Sim, R.B, Roversi, P, Johnson, S, Tang, C.M, Lea, S.M.
登録日2009-01-08
公開日2009-03-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Neisseria Meningitidis Recruits Factor H Using Protein Mimicry of Host Carbohydrates.
Nature, 458, 2009
4AQB
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BU of 4aqb by Molmil
MBL-Ficolin Associated Protein-1, MAP-1 aka MAP44
分子名称: CALCIUM ION, MANNAN-BINDING LECTIN SERINE PROTEASE 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Skjoedt, M.O, Roversi, P, Hummelshoj, T, Palarasah, Y, Johnson, S, Lea, S.M, Garred, P.
登録日2012-04-16
公開日2012-08-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Crystal Structure and Functional Characterization of the Complement Regulator Mannose-Binding Lectin (Mbl)/Ficolin-Associated Protein-1 (Map-1).
J.Biol.Chem., 287, 2012
4A9X
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BU of 4a9x by Molmil
Pseudomonas fluorescens PhoX in complex with the substrate analogue AppCp
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, MU-OXO-DIIRON, ...
著者Yong, S.C, Roversi, P, Lillington, J.E.D, Zeldin, O.B, Garman, E.F, Lea, S.M, Berks, B.C.
登録日2011-11-29
公開日2012-12-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献A Complex Iron-Calcium Cofactor Catalyzing Phosphotransfer Chemistry
Science, 345, 2014
6RQJ
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BU of 6rqj by Molmil
Structure of human complement C5 complexed with tick inhibitors OmCI, RaCI1 and CirpT1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5, Complement inhibitor, ...
著者Reichhardt, M.P, Johnson, S, Lea, S.M.
登録日2019-05-15
公開日2020-01-08
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献An inhibitor of complement C5 provides structural insights into activation.
Proc.Natl.Acad.Sci.USA, 117, 2020
4TT9
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BU of 4tt9 by Molmil
Structure of the C-terminal SpoA domain of Shigella flexneri Spa33
分子名称: 1,2-ETHANEDIOL, Surface presentation of antigens protein SpaO
著者McDowell, M.A, Johnson, S, Lea, S.M.
登録日2014-06-20
公開日2015-06-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Characterisation of Shigella Spa33 and Thermotoga FliM/N reveals a new model for C-ring assembly in T3SS.
Mol.Microbiol., 99, 2016
6RPT
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BU of 6rpt by Molmil
Structure of tick complement inhibitor CirpT1 complexed with macroglobubulin domain 4 of human complement C5
分子名称: Complement C5, GLYCEROL, Putative 8.9 kDa family member
著者Reichhardt, M.P, Lea, S.M, Johnson, S.
登録日2019-05-14
公開日2020-01-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An inhibitor of complement C5 provides structural insights into activation.
Proc.Natl.Acad.Sci.USA, 117, 2020
2YF2
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BU of 2yf2 by Molmil
Crystal structure of the oligomerisation domain of C4b-binding protein from Gallus gallus
分子名称: 1,2-ETHANEDIOL, ACETATE ION, C4B BINDING PROTEIN
著者Caesar, J.J.E, Hill, F, Lea, S.M.
登録日2011-04-01
公開日2012-04-18
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Crystal Structure of the Oligomerisation Domain of C4B-Binding Protein from Gallus Gallus
To be Published
6SAN
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SALSA / DMBT1 / GP340 SRCR domain 8 soaked in calcium and magnesium
分子名称: CHLORIDE ION, Deleted in malignant brain tumors 1 protein, GLYCEROL, ...
著者Reichhardt, M.P, Johnson, S, Loimaranta, V, Lea, S.M.
登録日2019-07-17
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR fold.
Life Sci Alliance, 3, 2020
5NQY
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BU of 5nqy by Molmil
Structure of a fHbp(V1.4):PorA(P1.16) chimera. Fusion at fHbp position 309.
分子名称: Factor H binding protein variant B16_001,Major outer membrane protein P.IA,Factor H binding protein variant B16_001
著者Johnson, S, Hollingshead, S, Lea, S.M, Tang, C.M.
登録日2017-04-21
公開日2018-02-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-based design of chimeric antigens for multivalent protein vaccines.
Nat Commun, 9, 2018
6SA4
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SALSA / DMBT1 / GP340 SRCR domain 1
分子名称: CHLORIDE ION, Deleted in malignant brain tumors 1 protein, GLYCEROL, ...
著者Reichhardt, M.P, Lea, S.M, Johnson, S.
登録日2019-07-16
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR fold.
Life Sci Alliance, 3, 2020
5NQX
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BU of 5nqx by Molmil
Structure of a fHbp(V1.1):PorA(P1.16) chimera. Fusion at fHbp position 294.
分子名称: Factor H binding protein,Major outer membrane protein P.IA,Factor H binding protein
著者Johnson, S, Jongerius, I, Lea, S.M, Tang, C.M.
登録日2017-04-21
公開日2018-02-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.66 Å)
主引用文献Structure-based design of chimeric antigens for multivalent protein vaccines.
Nat Commun, 9, 2018
2VT1
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BU of 2vt1 by Molmil
Crystal structure of the cytoplasmic domain of Spa40, the specificity switch for the Shigella flexneri Type III Secretion System
分子名称: SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAS
著者Deane, J.E, Graham, S.C, Mitchell, E.P, Flot, D, Johnson, S, Lea, S.M.
登録日2008-05-08
公開日2008-05-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Spa40, the Specificity Switch for the Shigella Flexneri Type III Secretion System
Mol.Microbiol., 69, 2008
4A5W
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BU of 4a5w by Molmil
Crystal structure of C5b6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C5, ...
著者Hadders, M.A, Bubeck, D, Forneris, F, Pangburn, M, Llorca, O, Lea, S.M, Gros, P.
登録日2011-10-28
公開日2012-03-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9.
Cell Rep., 1, 2012
5ACZ
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BU of 5acz by Molmil
COMPLEX OF A B21 CHICKEN MHC CLASS I MOLECULE AND A 11MER CHICKEN PEPTIDE
分子名称: 1,2-ETHANEDIOL, 11MER PEPTIDE, BETA-2-MICROGLOBULIN, ...
著者Chappell, P.E, Roversi, P, Harrison, M.C, Kaufman, J.F, Lea, S.M.
登録日2015-08-19
公開日2016-09-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Complex of a B21 Chicken Mhc Class I Molecule and a 11mer Chicken Peptide
To be Published
5AD0
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BU of 5ad0 by Molmil
COMPLEX OF A B21 CHICKEN MHC CLASS I MOLECULE AND A 11MER CHICKEN PEPTIDE
分子名称: 1,2-ETHANEDIOL, 11MER PEPTIDE, BETA-2-MICROGLOBULIN, ...
著者Chappell, P.E, Roversi, P, Harrison, M.C, Kaufman, J.F, Lea, S.M.
登録日2015-08-19
公開日2016-09-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Complex of a B21 Chicken Mhc Class I Molecule and a 11mer Chicken Peptide
To be Published
2UXT
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BU of 2uxt by Molmil
SufI Protein from Escherichia Coli
分子名称: PROTEIN SUFI
著者Tarry, M.J, Roversi, P, Sargent, F, Berks, B.C, Lea, S.M.
登録日2007-03-29
公開日2008-05-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Escherichia Coli Cell Division Protein and Model Tat Substrate Sufi (Ftsp) Localizes to the Septal Ring and Has a Multicopper Oxidase-Like Structure.
J.Mol.Biol., 386, 2009
2UXV
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BU of 2uxv by Molmil
SufI Protein from Escherichia Coli
分子名称: PROTEIN SUFI
著者Tarry, M.J, Roversi, P, Sargent, F, Berks, B.C, Lea, S.M.
登録日2007-03-30
公開日2008-05-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献The Escherichia Coli Cell Division Protein and Model Tat Substrate Sufi (Ftsp) Localizes to the Septal Ring and Has a Multicopper Oxidase-Like Structure.
J.Mol.Biol., 386, 2009
5MWE
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BU of 5mwe by Molmil
Complex between the Leucine Zipper (LZ, residues 490-567) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn)
分子名称: 1,2-ETHANEDIOL, 3,3',3''-phosphanetriyltripropanoic acid, Centrosomin, ...
著者Feng, Z, Johnson, S, Raff, J.W, Lea, S.M.
登録日2017-01-18
公開日2017-06-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
5MW9
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Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) - L535E mutant form
分子名称: Centrosomin, ZINC ION
著者Feng, Z, Johnson, S, Raff, J.W, Lea, S.M.
登録日2017-01-18
公開日2017-06-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
5MVW
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BU of 5mvw by Molmil
Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Centrosomin, ...
著者Feng, Z, Johnson, S, Raff, J.W, Lea, S.M.
登録日2017-01-17
公開日2017-06-28
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
5MW0
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BU of 5mw0 by Molmil
Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) - L535E mutant form
分子名称: Centrosomin, ZINC ION
著者Feng, Z, Johnson, S, Raff, J.W, Lea, S.M.
登録日2017-01-17
公開日2017-06-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
2VJ4
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BU of 2vj4 by Molmil
Methylated Shigella flexneri MxiC
分子名称: PROTEIN MXIC
著者Deane, J.E, Roversi, P, King, C, Johnson, S, Lea, S.M.
登録日2007-12-06
公開日2008-03-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of the Shigella Flexneri Type 3 Secretion System Protein Mxic Reveal Conformational Variability Amongst Homologues.
J.Mol.Biol., 377, 2008
2WDC
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BU of 2wdc by Molmil
Termus thermophilus Sulfate thiohydrolase SoxB in complex with glycerol
分子名称: ACETATE ION, GLYCEROL, MANGANESE (II) ION, ...
著者Sauve, V, Roversi, P, Leath, K.J, Garman, E.F, Antrobus, R, Lea, S.M, Berks, B.C.
登録日2009-03-24
公開日2009-06-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Mechanism for the Hydrolysis of a Sulfur-Sulfur Bond Based on the Crystal Structure of the Thiosulfohydrolase Soxb.
J.Biol.Chem., 284, 2009
5HCD
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BU of 5hcd by Molmil
Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Rhipicephalus microplus RaCI2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, Complement C5, ...
著者Jore, M.M, Johnson, S, Lea, S.M.
登録日2016-01-04
公開日2016-03-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Structural basis for therapeutic inhibition of complement C5.
Nat.Struct.Mol.Biol., 23, 2016
2W5P
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DraE Adhesin in complex with Chloramphenicol Succinate (monoclinic form)
分子名称: CHLORAMPHENICOL SUCCINATE, DR HEMAGGLUTININ STRUCTURAL SUBUNIT, SULFATE ION
著者Pettigrew, D.M, Roversi, P, Davies, S.G, Russell, A.J, Lea, S.M.
登録日2008-12-11
公開日2009-06-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Structural Study of the Interaction between the Dr Haemagglutinin Drae and Derivatives of Chloramphenicol
Acta Crystallogr.,Sect.D, 65, 2009

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