6D3X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d3x by Molmil](/molmil-images/mine/6d3x) | |
6DN5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dn5 by Molmil](/molmil-images/mine/6dn5) | |
6DN8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dn8 by Molmil](/molmil-images/mine/6dn8) | SPRY domain-containing SOCS box protein 2 complexed with (GZJ)VDINNN(CY3) Cyclic peptide inhibitor | 分子名称: | (GZJ)VDINNN(CY3) Cyclic peptide inhibitor, ACETATE ION, SPRY domain-containing SOCS box protein 4, ... | 著者 | Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S. | 登録日 | 2018-06-06 | 公開日 | 2019-04-17 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent. ACS Chem. Biol., 13, 2018
|
|
6NMB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nmb by Molmil](/molmil-images/mine/6nmb) | |
6D3Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d3z by Molmil](/molmil-images/mine/6d3z) | Protease SFTI complex | 分子名称: | Plasminogen, Trypsin inhibitor 1 | 著者 | Law, R.H.P, Wu, G. | 登録日 | 2018-04-17 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma. J. Med. Chem., 62, 2019
|
|
6DN7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dn7 by Molmil](/molmil-images/mine/6dn7) | |
6D40
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d40 by Molmil](/molmil-images/mine/6d40) | |
6D3Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d3y by Molmil](/molmil-images/mine/6d3y) | |
6DN6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dn6 by Molmil](/molmil-images/mine/6dn6) | |
6OG4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6og4 by Molmil](/molmil-images/mine/6og4) | plasminogen binding group A streptococcal M protein | 分子名称: | Plasminogen, Plasminogen-binding group A streptococcal M-like protein PAM, SULFATE ION | 著者 | Law, R.H.P, Quek, A.J, Whisstock, J.C, Caradoc-Davies, T.T. | 登録日 | 2019-04-01 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding. J.Mol.Biol., 431, 2019
|
|
5UGG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ugg by Molmil](/molmil-images/mine/5ugg) | Protease Inhibitor | 分子名称: | Nalpha-[trans-4-(aminomethyl)cyclohexane-1-carbonyl]-N-octyl-O-[(quinolin-2-yl)methyl]-L-tyrosinamide, Plasminogen | 著者 | Law, R.H.P, Wu, G, Whisstock, J.C. | 登録日 | 2017-01-08 | 公開日 | 2017-05-31 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors. Blood Adv, 1, 2017
|
|
5UG7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ug7 by Molmil](/molmil-images/mine/5ug7) | Calcium bound Perforin C2 Domain - T431D | 分子名称: | CALCIUM ION, Perforin-1 | 著者 | Law, R.H.P, Conroy, P.J, Voskoboinik, I, Whisstock, J.C. | 登録日 | 2017-01-07 | 公開日 | 2018-02-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin. Cell Death Differ., 25, 2018
|
|
5UG6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ug6 by Molmil](/molmil-images/mine/5ug6) | Perforin C2 Domain - T431D | 分子名称: | IODIDE ION, Perforin-1 | 著者 | Law, R.H.P, Conroy, P.J, Voskoboinik, I, Whisstock, J.C. | 登録日 | 2017-01-07 | 公開日 | 2018-02-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin. Cell Death Differ., 25, 2018
|
|
5UGD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ugd by Molmil](/molmil-images/mine/5ugd) | Protease Inhibitor | 分子名称: | Nalpha-[trans-4-(aminomethyl)cyclohexane-1-carbonyl]-N-octyl-O-[(pyridin-4-yl)methyl]-L-tyrosinamide, Plasminogen | 著者 | Law, R.H.P, Wu, G, Whisstock, J.C. | 登録日 | 2017-01-08 | 公開日 | 2017-05-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors. Blood Adv, 1, 2017
|
|
6CXO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cxo by Molmil](/molmil-images/mine/6cxo) | Complement component-9 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement component C9, ... | 著者 | Law, R.H.P, Spicer, B.A, Caradoc-Davies, T.T. | 登録日 | 2018-04-03 | 公開日 | 2018-09-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The first transmembrane region of complement component-9 acts as a brake on its self-assembly. Nat Commun, 9, 2018
|
|
2R9Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2r9y by Molmil](/molmil-images/mine/2r9y) | Structure of antiplasmin | 分子名称: | Alpha-2-antiplasmin | 著者 | Law, R.H.P, Sofian, T, Kan, W.T, Horvath, A.J, Hitchen, C.R, Langendorf, C.G, Buckle, A.M, Whisstock, J.C, Coughlin, P.B. | 登録日 | 2007-09-14 | 公開日 | 2007-12-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | X-ray crystal structure of the fibrinolysis inhibitor {alpha}2-antiplasmin Blood, 111, 2008
|
|
4DUR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4dur by Molmil](/molmil-images/mine/4dur) | The X-ray Crystal Structure of Full-Length type II Human Plasminogen | 分子名称: | ACETATE ION, BICARBONATE ION, CHLORIDE ION, ... | 著者 | Law, R.H.P, Caradoc-Davies, T, Whisstock, J.C. | 登録日 | 2012-02-22 | 公開日 | 2012-03-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | The X-ray crystal structure of full-length human plasminogen Cell Rep, 1, 2012
|
|
4DUU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4duu by Molmil](/molmil-images/mine/4duu) | |
4V2T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v2t by Molmil](/molmil-images/mine/4v2t) | Membrane embedded pleurotolysin pore with 13 fold symmetry | 分子名称: | PLEUROTOLYSIN A, PLEUROTOLYSIN B | 著者 | Lukoyanova, N, Kondos, S.C, Farabella, I, Law, R.H.P, Reboul, C.F, Caradoc-Davies, T.T, Spicer, B.A, Kleifeld, O, Perugini, M, Ekkel, S, Hatfaludi, T, Oliver, K, Hotze, E.M, Tweten, R.K, Whisstock, J.C, Topf, M, Dunstone, M.A, Saibil, H.R. | 登録日 | 2014-10-15 | 公開日 | 2015-02-18 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (11 Å) | 主引用文献 | Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin. Plos Biol., 13, 2015
|
|
4OV8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ov8 by Molmil](/molmil-images/mine/4ov8) | Crystal Structure of the TMH1-lock mutant of the mature form of pleurotolysin B | 分子名称: | CHLORIDE ION, GLYCEROL, Pleurotolysin B, ... | 著者 | Kondos, S.C, Law, R.H.P, Whisstock, J.C, Dunstone, M.A. | 登録日 | 2014-02-20 | 公開日 | 2015-02-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin Plos Biol., 13, 2015
|
|
4OEB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oeb by Molmil](/molmil-images/mine/4oeb) | Structure of membrane binding protein pleurotolysin A from Pleurotus ostreatus | 分子名称: | Pleurotolysin A, SULFATE ION | 著者 | Dunstone, M.A, Caradoc-Davies, T.T, Whisstock, J.C, Law, R.H.P. | 登録日 | 2014-01-12 | 公開日 | 2015-02-18 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin. Plos Biol., 13, 2015
|
|
4P48
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4p48 by Molmil](/molmil-images/mine/4p48) | The structure of a chicken anti-cardiac Troponin I scFv | 分子名称: | Antibody scFv 180 | 著者 | Conroy, P.J, Law, R.H.P, Gillgunn, S, Hearty, S, Caradoc-Davies, T.T, Llyod, G, O'Kennedy, R.J, Whisstock, J.C. | 登録日 | 2014-03-12 | 公開日 | 2014-04-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Reconciling the structural attributes of avian antibodies. J.Biol.Chem., 289, 2014
|
|
4P49
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4p49 by Molmil](/molmil-images/mine/4p49) | The structure of a chicken anti-prostate specific antigen scFv | 分子名称: | ACETATE ION, Antibody scFv B8, SULFATE ION | 著者 | Conroy, P.J, Law, R.H.P, Gilgunn, S, Hearty, S, Llyod, G, Caradoc-Davies, T.T, O'Kennedy, R.J, Whisstock, J.C. | 登録日 | 2014-03-12 | 公開日 | 2014-04-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Reconciling the structural attributes of avian antibodies. J.Biol.Chem., 289, 2014
|
|
4V3A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v3a by Molmil](/molmil-images/mine/4v3a) | Membrane bound pleurotolysin prepore (TMH1 lock) trapped with engineered disulphide cross-link | 分子名称: | PLEUROTOLYSIN A, PLEUROTOLYSIN B | 著者 | Lukoyanova, N, Kondos, S.C, Farabella, I, Law, R.H.P, Reboul, C.F, CaradocDavies, T.T, Spicer, B.A, Kleifeld, O, Perugini, M, Ekkel, S, Hatfaludi, T, Oliver, K, Hotze, E.M, Tweten, R.K, Whisstock, J.C, Topf, M, Dunstone, M.A, Saibil, H.R. | 登録日 | 2014-10-17 | 公開日 | 2015-02-18 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (15 Å) | 主引用文献 | Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin. Plos Biol., 13, 2015
|
|
4V3M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v3m by Molmil](/molmil-images/mine/4v3m) | Membrane bound pleurotolysin prepore (TMH2 helix lock) trapped with engineered disulphide cross-link | 分子名称: | PLEUROTOLYSIN A, PLEUROTOLYSIN B | 著者 | Lukoyanova, N, Kondos, S.C, Farabella, I, Law, R.H.P, Reboul, C.F, Caradoc-Davies, T.T, Spicer, B.A, Kleifeld, O, Perugini, M, Ekkel, S, Hatfaludi, T, Oliver, K, Hotze, E.M, Tweten, R.K, Whisstock, J.C, Topf, M, Dunstone, M.A, Saibil, H.R. | 登録日 | 2014-10-20 | 公開日 | 2015-02-18 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (17 Å) | 主引用文献 | Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin. Plos Biol., 13, 2015
|
|