6QDK
 
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4A8D
 | | DegP dodecamer with bound OMP | | Descriptor: | OUTER MEMBRANE PROTEIN C, PERIPLASMIC SERINE ENDOPROTEASE DEGP | | Authors: | Malet, H, Krojer, T, Sawa, J, Schafer, E, Saibil, H.R, Ehrmann, M, Clausen, T. | | Deposit date: | 2011-11-20 | | Release date: | 2012-01-11 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (28 Å) | | Cite: | Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
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1QGN
 | | CYSTATHIONINE GAMMA-SYNTHASE FROM NICOTIANA TABACUM | | Descriptor: | PROTEIN (CYSTATHIONINE GAMMA-SYNTHASE), PYRIDOXAL-5'-PHOSPHATE | | Authors: | Steegborn, C, Messerschmidt, A, Laber, B, Streber, W, Huber, R, Clausen, T. | | Deposit date: | 1999-05-02 | | Release date: | 1999-08-25 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The crystal structure of cystathionine gamma-synthase from Nicotiana tabacum reveals its substrate and reaction specificity.
J.Mol.Biol., 290, 1999
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5HBN
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1Z41
 | | Crystal structure of oxidized YqjM from Bacillus subtilis | | Descriptor: | FLAVIN MONONUCLEOTIDE, Probable NADH-dependent flavin oxidoreductase yqjM, SULFATE ION | | Authors: | Kitzing, K, Fitzpatrick, T.B, Wilken, C, Sawa, J, Bourenkov, G.P, Macheroux, P, Clausen, T. | | Deposit date: | 2005-03-15 | | Release date: | 2005-05-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | The 1.3 A Crystal Structure of the Flavoprotein YqjM Reveals a Novel Class of Old Yellow Enzymes
J.Biol.Chem., 280, 2005
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1Z48
 | | Crystal structure of reduced YqjM from Bacillus subtilis | | Descriptor: | FLAVIN MONONUCLEOTIDE, Probable NADH-dependent flavin oxidoreductase yqjM | | Authors: | Kitzing, K, Fitzpatrick, T.B, Wilken, C, Sawa, J, Bourenkov, G.P, Macheroux, P, Clausen, T. | | Deposit date: | 2005-03-15 | | Release date: | 2005-05-17 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The 1.3 A Crystal Structure of the Flavoprotein YqjM Reveals a Novel Class of Old Yellow Enzymes
J.Biol.Chem., 280, 2005
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1Z44
 | | Crystal structure of oxidized YqjM from Bacillus subtilis complexed with p-nitrophenol | | Descriptor: | FLAVIN MONONUCLEOTIDE, P-NITROPHENOL, Probable NADH-dependent flavin oxidoreductase yqjM, ... | | Authors: | Kitzing, K, Fitzpatrick, T.B, Wilken, C, Sawa, J, Bourenkov, G.P, Macheroux, P, Clausen, T. | | Deposit date: | 2005-03-15 | | Release date: | 2005-05-17 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The 1.3 A Crystal Structure of the Flavoprotein YqjM Reveals a Novel Class of Old Yellow Enzymes
J.Biol.Chem., 280, 2005
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1SOT
 | | Crystal Structure of the DegS stress sensor | | Descriptor: | Protease degS | | Authors: | Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T. | | Deposit date: | 2004-03-15 | | Release date: | 2004-06-08 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
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7AA4
 | | Structure of ClpC1-NTD bound to a CymA analogue | | Descriptor: | Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue | | Authors: | Meinhart, A, Morreale, F.E, Kaiser, M, Clausen, T. | | Deposit date: | 2020-09-03 | | Release date: | 2021-08-11 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
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8ATX
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8ATU
 | | Cryo-EM structure of human BIRC6 | | Descriptor: | Baculoviral IAP repeat-containing protein 6, ZINC ION | | Authors: | Ehrmann, J.F, Grabarczyk, D.B, Clausen, T. | | Deposit date: | 2022-08-24 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex.
Science, 379, 2023
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8AUW
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8AUK
 | | Cryo-EM structure of human BIRC6 in complex with HTRA2. | | Descriptor: | Baculoviral IAP repeat-containing protein 6, Serine protease HTRA2, mitochondrial, ... | | Authors: | Ehrmann, J.F, Grabarczyk, D.B, Clausen, T. | | Deposit date: | 2022-08-25 | | Release date: | 2023-02-15 | | Last modified: | 2023-05-24 | | Method: | ELECTRON MICROSCOPY (6.2 Å) | | Cite: | Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex.
Science, 379, 2023
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8B9O
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8B9U
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5D4W
 | | Crystal structure of Hsp104 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Putative heat shock protein | | Authors: | Heuck, A, Schitter-Sollner, S, Clausen, T. | | Deposit date: | 2015-08-09 | | Release date: | 2016-12-07 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Structural basis for the disaggregase activity and regulation of Hsp104.
Elife, 5, 2016
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7ABR
 | | Cryo-EM structure of B. subtilis ClpC (DWB mutant) hexamer bound to a substrate polypeptide | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Negative regulator of genetic competence ClpC/MecB, ... | | Authors: | Morreale, F.E, Meinhart, A, Haselbach, D, Clausen, T. | | Deposit date: | 2020-09-08 | | Release date: | 2021-10-06 | | Last modified: | 2022-07-06 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
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1K5J
 | | The Crystal Structure of Nucleoplasmin-Core | | Descriptor: | Nucleoplasmin Core | | Authors: | Dutta, S, Akey, I.V, Dingwall, C, Hartman, K.L, Laue, T, Nolte, R.T, Head, J.F, Akey, C.W. | | Deposit date: | 2001-10-10 | | Release date: | 2001-11-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The crystal structure of nucleoplasmin-core: implications for histone binding and nucleosome assembly.
Mol.Cell, 8, 2001
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8BRG
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1KY9
 | | Crystal Structure of DegP (HtrA) | | Descriptor: | PROTEASE DO | | Authors: | Krojer, T, Garrido-Franco, M, Huber, R, Ehrmann, M, Clausen, T. | | Deposit date: | 2002-02-04 | | Release date: | 2002-04-03 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine.
Nature, 416, 2002
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1SOZ
 | | Crystal Structure of DegS protease in complex with an activating peptide | | Descriptor: | Protease degS, activating peptide | | Authors: | Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T. | | Deposit date: | 2004-03-16 | | Release date: | 2004-06-08 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
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1VCW
 | | Crystal structure of DegS after backsoaking the activating peptide | | Descriptor: | Protease degS | | Authors: | Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T. | | Deposit date: | 2004-03-16 | | Release date: | 2004-06-08 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease.
Cell(Cambridge,Mass.), 117, 2004
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1ECX
 | | NIFS-LIKE PROTEIN | | Descriptor: | AMINOTRANSFERASE, CYSTEINE, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Kaiser, J.T, Clausen, T.C, Bourenkow, G.P, Bartunik, H.-D, Steinbacher, S, Huber, R. | | Deposit date: | 2000-01-26 | | Release date: | 2000-03-20 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of a NifS-like protein from Thermotoga maritima: implications for iron sulphur cluster assembly.
J.Mol.Biol., 297, 2000
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1I41
 | | CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR APPA | | Descriptor: | 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-IMINO]-5-PHOSPHONO-PENT-3-ENOIC ACID, CYSTATHIONINE GAMMA-SYNTHASE | | Authors: | Steegborn, C, Laber, B, Messerschmidt, A, Huber, R, Clausen, T. | | Deposit date: | 2001-02-19 | | Release date: | 2001-09-05 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor.
J.Mol.Biol., 311, 2001
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1I43
 | | CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR PPCA | | Descriptor: | 3-(PHOSPHONOMETHYL)PYRIDINE-2-CARBOXYLIC ACID, CYSTATHIONINE GAMMA-SYNTHASE, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Steegborn, C, Laber, B, Messerschmidt, A, Huber, R, Clausen, T. | | Deposit date: | 2001-02-19 | | Release date: | 2001-09-05 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor.
J.Mol.Biol., 311, 2001
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