1I41
CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR APPA
Summary for 1I41
| Entry DOI | 10.2210/pdb1i41/pdb |
| Related | 1qgn |
| Descriptor | CYSTATHIONINE GAMMA-SYNTHASE, 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-IMINO]-5-PHOSPHONO-PENT-3-ENOIC ACID (2 entities in total) |
| Functional Keywords | plp-dependent enzyme, homotetramer, inhibitor complex, appa, lyase |
| Biological source | Nicotiana tabacum (common tobacco) |
| Total number of polymer chains | 12 |
| Total formula weight | 581906.52 |
| Authors | Steegborn, C.,Laber, B.,Messerschmidt, A.,Huber, R.,Clausen, T. (deposition date: 2001-02-19, release date: 2001-09-05, Last modification date: 2023-08-09) |
| Primary citation | Steegborn, C.,Laber, B.,Messerschmidt, A.,Huber, R.,Clausen, T. Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor. J.Mol.Biol., 311:789-801, 2001 Cited by PubMed: 11518531DOI: 10.1006/jmbi.2001.4880 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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