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PDB: 151 件
6QDK
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Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
分子名称: UNC-45,UNC-45
著者Meinhart, A, Clausen, T, Hellerschmied, D.
登録日2019-01-02
公開日2019-10-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
4A8D
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DegP dodecamer with bound OMP
分子名称: OUTER MEMBRANE PROTEIN C, PERIPLASMIC SERINE ENDOPROTEASE DEGP
著者Malet, H, Krojer, T, Sawa, J, Schafer, E, Saibil, H.R, Ehrmann, M, Clausen, T.
登録日2011-11-20
公開日2012-01-11
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (28 Å)
主引用文献Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
1QGN
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CYSTATHIONINE GAMMA-SYNTHASE FROM NICOTIANA TABACUM
分子名称: PROTEIN (CYSTATHIONINE GAMMA-SYNTHASE), PYRIDOXAL-5'-PHOSPHATE
著者Steegborn, C, Messerschmidt, A, Laber, B, Streber, W, Huber, R, Clausen, T.
登録日1999-05-02
公開日1999-08-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The crystal structure of cystathionine gamma-synthase from Nicotiana tabacum reveals its substrate and reaction specificity.
J.Mol.Biol., 290, 1999
5HBN
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ClpC N-terminal domain with bound phospho-arginine
分子名称: ACETATE ION, Negative regulator of genetic competence ClpC/MecB, SULFATE ION, ...
著者Suskiewicz, M.J, Clausen, T.
登録日2016-01-01
公開日2016-10-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Arginine phosphorylation marks proteins for degradation by a Clp protease.
Nature, 539, 2016
1Z41
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Crystal structure of oxidized YqjM from Bacillus subtilis
分子名称: FLAVIN MONONUCLEOTIDE, Probable NADH-dependent flavin oxidoreductase yqjM, SULFATE ION
著者Kitzing, K, Fitzpatrick, T.B, Wilken, C, Sawa, J, Bourenkov, G.P, Macheroux, P, Clausen, T.
登録日2005-03-15
公開日2005-05-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The 1.3 A Crystal Structure of the Flavoprotein YqjM Reveals a Novel Class of Old Yellow Enzymes
J.Biol.Chem., 280, 2005
1Z48
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Crystal structure of reduced YqjM from Bacillus subtilis
分子名称: FLAVIN MONONUCLEOTIDE, Probable NADH-dependent flavin oxidoreductase yqjM
著者Kitzing, K, Fitzpatrick, T.B, Wilken, C, Sawa, J, Bourenkov, G.P, Macheroux, P, Clausen, T.
登録日2005-03-15
公開日2005-05-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The 1.3 A Crystal Structure of the Flavoprotein YqjM Reveals a Novel Class of Old Yellow Enzymes
J.Biol.Chem., 280, 2005
1Z44
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Crystal structure of oxidized YqjM from Bacillus subtilis complexed with p-nitrophenol
分子名称: FLAVIN MONONUCLEOTIDE, P-NITROPHENOL, Probable NADH-dependent flavin oxidoreductase yqjM, ...
著者Kitzing, K, Fitzpatrick, T.B, Wilken, C, Sawa, J, Bourenkov, G.P, Macheroux, P, Clausen, T.
登録日2005-03-15
公開日2005-05-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The 1.3 A Crystal Structure of the Flavoprotein YqjM Reveals a Novel Class of Old Yellow Enzymes
J.Biol.Chem., 280, 2005
1SOT
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BU of 1sot by Molmil
Crystal Structure of the DegS stress sensor
分子名称: Protease degS
著者Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
登録日2004-03-15
公開日2004-06-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
7AA4
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Structure of ClpC1-NTD bound to a CymA analogue
分子名称: Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue
著者Meinhart, A, Morreale, F.E, Kaiser, M, Clausen, T.
登録日2020-09-03
公開日2021-08-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
8ATX
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BU of 8atx by Molmil
Cryo-EM structure of human BIRC6 - no substrate
分子名称: Baculoviral IAP repeat-containing protein 6, ZINC ION
著者Ehrmann, J.F, Grabarczyk, D.B, Clausen, T.
登録日2022-08-24
公開日2023-02-15
最終更新日2023-03-29
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex.
Science, 379, 2023
8ATU
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BU of 8atu by Molmil
Cryo-EM structure of human BIRC6
分子名称: Baculoviral IAP repeat-containing protein 6, ZINC ION
著者Ehrmann, J.F, Grabarczyk, D.B, Clausen, T.
登録日2022-08-24
公開日2023-02-15
最終更新日2023-03-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex.
Science, 379, 2023
8AUW
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Cryo-EM structure of human BIRC6 in complex with SMAC.
分子名称: Baculoviral IAP repeat-containing protein 6, Diablo IAP-binding mitochondrial protein, ZINC ION
著者Ehrmann, J.F, Grabarczyk, D.B, Clausen, T.
登録日2022-08-25
公開日2023-02-15
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex.
Science, 379, 2023
8AUK
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Cryo-EM structure of human BIRC6 in complex with HTRA2.
分子名称: Baculoviral IAP repeat-containing protein 6, Serine protease HTRA2, mitochondrial, ...
著者Ehrmann, J.F, Grabarczyk, D.B, Clausen, T.
登録日2022-08-25
公開日2023-02-15
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex.
Science, 379, 2023
8B9O
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BU of 8b9o by Molmil
Structure of the C-terminal domain of ClpC2 from Mycobacterium smegmatis
分子名称: Clp amino terminal domain protein, phospho-arginine
著者Meinhart, A, Hoi, D.M, Clausen, T.
登録日2022-10-06
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Cell, 186, 2023
8B9U
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BU of 8b9u by Molmil
Structure of ClpC1 NTD from Mycobacterium tuberculosis
分子名称: (MLE)V(MAA)(E9M)G, ATP-dependent Clp protease ATP-binding subunit ClpC1, FORMIC ACID
著者Meinhart, A, Hoi, D.M, Clausen, T.
登録日2022-10-10
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Cell, 186, 2023
5D4W
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BU of 5d4w by Molmil
Crystal structure of Hsp104
分子名称: ADENOSINE-5'-DIPHOSPHATE, Putative heat shock protein
著者Heuck, A, Schitter-Sollner, S, Clausen, T.
登録日2015-08-09
公開日2016-12-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structural basis for the disaggregase activity and regulation of Hsp104.
Elife, 5, 2016
7ABR
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BU of 7abr by Molmil
Cryo-EM structure of B. subtilis ClpC (DWB mutant) hexamer bound to a substrate polypeptide
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Negative regulator of genetic competence ClpC/MecB, ...
著者Morreale, F.E, Meinhart, A, Haselbach, D, Clausen, T.
登録日2020-09-08
公開日2021-10-06
最終更新日2022-07-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
1K5J
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BU of 1k5j by Molmil
The Crystal Structure of Nucleoplasmin-Core
分子名称: Nucleoplasmin Core
著者Dutta, S, Akey, I.V, Dingwall, C, Hartman, K.L, Laue, T, Nolte, R.T, Head, J.F, Akey, C.W.
登録日2001-10-10
公開日2001-11-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of nucleoplasmin-core: implications for histone binding and nucleosome assembly.
Mol.Cell, 8, 2001
8BRG
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BU of 8brg by Molmil
Crystal structure of She4
分子名称: KLLA0E16699p
著者Gudino, R, Arnese, R, Meinhart, A, Clausen, T.
登録日2022-11-23
公開日2024-06-05
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献UNC-45 assisted myosin folding depends on a conserved FX3HY motif implicated in Freeman Sheldon Syndrome
bioRxiv, 2022
1KY9
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BU of 1ky9 by Molmil
Crystal Structure of DegP (HtrA)
分子名称: PROTEASE DO
著者Krojer, T, Garrido-Franco, M, Huber, R, Ehrmann, M, Clausen, T.
登録日2002-02-04
公開日2002-04-03
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine.
Nature, 416, 2002
1SOZ
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BU of 1soz by Molmil
Crystal Structure of DegS protease in complex with an activating peptide
分子名称: Protease degS, activating peptide
著者Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
登録日2004-03-16
公開日2004-06-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
1VCW
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BU of 1vcw by Molmil
Crystal structure of DegS after backsoaking the activating peptide
分子名称: Protease degS
著者Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
登録日2004-03-16
公開日2004-06-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease.
Cell(Cambridge,Mass.), 117, 2004
1ECX
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BU of 1ecx by Molmil
NIFS-LIKE PROTEIN
分子名称: AMINOTRANSFERASE, CYSTEINE, PYRIDOXAL-5'-PHOSPHATE
著者Kaiser, J.T, Clausen, T.C, Bourenkow, G.P, Bartunik, H.-D, Steinbacher, S, Huber, R.
登録日2000-01-26
公開日2000-03-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a NifS-like protein from Thermotoga maritima: implications for iron sulphur cluster assembly.
J.Mol.Biol., 297, 2000
1I41
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CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR APPA
分子名称: 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-IMINO]-5-PHOSPHONO-PENT-3-ENOIC ACID, CYSTATHIONINE GAMMA-SYNTHASE
著者Steegborn, C, Laber, B, Messerschmidt, A, Huber, R, Clausen, T.
登録日2001-02-19
公開日2001-09-05
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor.
J.Mol.Biol., 311, 2001
1I43
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CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR PPCA
分子名称: 3-(PHOSPHONOMETHYL)PYRIDINE-2-CARBOXYLIC ACID, CYSTATHIONINE GAMMA-SYNTHASE, PYRIDOXAL-5'-PHOSPHATE
著者Steegborn, C, Laber, B, Messerschmidt, A, Huber, R, Clausen, T.
登録日2001-02-19
公開日2001-09-05
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor.
J.Mol.Biol., 311, 2001

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