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PDB: 21 件

5VVS
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RNA pol II elongation complex
分子名称: DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ...
著者Lahiri, I, Leschziner, A.E.
登録日2017-05-20
公開日2017-11-22
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Structural basis for the initiation of eukaryotic transcription-coupled DNA repair.
Nature, 551, 2017
5VVR
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Ternary complex of RNA Pol II, transcription scaffold and Rad26
分子名称: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ...
著者Lahiri, I, Leschziner, A.E.
登録日2017-05-19
公開日2017-11-22
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Structural basis for the initiation of eukaryotic transcription-coupled DNA repair.
Nature, 551, 2017
7MGM
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Structure of yeast cytoplasmic dynein with AAA3 Walker B mutation bound to Lis1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Lahiri, I, Reimer, J.M, Leschziner, A.E.
登録日2021-04-12
公開日2022-01-19
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for cytoplasmic dynein-1 regulation by Lis1.
Elife, 11, 2022
6O6C
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RNA polymerase II elongation complex arrested at a CPD lesion
分子名称: DNA (27-MER), DNA (5'-D(P*GP*GP*AP*GP*AP*AP*GP*GP*AP*GP*CP*AP*GP*AP*GP*C)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
著者Lahiri, I, Leshziner, A.E.
登録日2019-03-05
公開日2019-06-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献3.1 angstrom structure of yeast RNA polymerase II elongation complex stalled at a cyclobutane pyrimidine dimer lesion solved using streptavidin affinity grids.
J.Struct.Biol., 207, 2019
6DRV
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BU of 6drv by Molmil
Beta-galactosidase
分子名称: Beta-galactosidase
著者Cianfrocco, M.A, Lahiri, I, DiMaio, F, Leschziner, A.E.
登録日2018-06-13
公開日2018-07-11
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献cryoem-cloud-tools: A software platform to deploy and manage cryo-EM jobs in the cloud.
J. Struct. Biol., 203, 2018
7YL9
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BU of 7yl9 by Molmil
Cryo-EM structure of complete transmembrane channel E289A mutant Vibrio cholerae Cytolysin
分子名称: Hemolysin
著者Mondal, A.K, Sengupta, N, Singh, M, Biswas, R, Lata, K, Lahiri, I, Dutta, S, Chattopadhyay, K.
登録日2022-07-25
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Cryo-EM structure of complete transmembrane channel E289A mutant Vibrio cholerae Cytolysin
J.Biol.Chem.
7LGM
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Cyanophycin synthetase from A. baylyi DSM587 with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyanophycin synthase
著者Sharon, I, Haque, A.S, Lahiri, I, Leschziner, A, Schmeing, T.M.
登録日2021-01-20
公開日2021-08-18
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structures and function of the amino acid polymerase cyanophycin synthetase.
Nat.Chem.Biol., 17, 2021
8DZZ
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Cryo-EM structure of chi dynein bound to Lis1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
著者Reimer, J.M, Lahiri, I, Leschziner, A.E.
登録日2022-08-08
公開日2023-08-30
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge.
Nat.Struct.Mol.Biol., 30, 2023
8E00
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Symmetry expansion of yeast cytoplasmic dynein-1 bound to Lis1 in the chi conformation.
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
著者Reimer, J.M, Lahiri, I, Leschziner, A.E.
登録日2022-08-08
公開日2023-08-30
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge.
Nat.Struct.Mol.Biol., 30, 2023
6VNO
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Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
著者Leschziner, A, Deniston, C, Lahiri, I.
登録日2020-01-29
公開日2020-08-26
最終更新日2020-12-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP8
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Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
分子名称: Leucine-rich repeat serine/threonine-protein kinase 2
著者Leschziner, A, Deniston, C, Lahiri, I.
登録日2020-02-01
公開日2020-08-26
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP6
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Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
著者Leschziner, A, Deniston, C, Lahiri, I.
登録日2020-02-01
公開日2020-08-26
最終更新日2020-12-23
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP7
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BU of 6vp7 by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
分子名称: Leucine-rich repeat serine/threonine-protein kinase 2
著者Leschziner, A, Deniston, C, Lahiri, I.
登録日2020-02-01
公開日2020-08-26
最終更新日2020-12-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
8TVP
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BU of 8tvp by Molmil
Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (open state)
分子名称: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-18
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVV
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BU of 8tvv by Molmil
Cryo-EM structure of backtracked Pol II
分子名称: DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-18
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVQ
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BU of 8tvq by Molmil
Cryo-EM structure of CPD stalled 10-subunit Pol II in complex with Rad26
分子名称: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-18
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVY
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BU of 8tvy by Molmil
Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state)
分子名称: DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-18
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVX
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BU of 8tvx by Molmil
Cryo-EM structure of CPD-stalled Pol II (Conformation 2)
分子名称: DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-18
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVW
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BU of 8tvw by Molmil
Cryo-EM structure of CPD-stalled Pol II (conformation 1)
分子名称: DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-18
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVS
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BU of 8tvs by Molmil
Cryo-EM structure of backtracked Pol II in complex with Rad26
分子名称: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-18
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TUG
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BU of 8tug by Molmil
Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (engaged state)
分子名称: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-16
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024

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件を2024-07-17に公開中

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