8TVY

Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state)

Summary for 8TVY

Entry DOI	10.2210/pdb8tvy/pdb
EMDB information	41655
Descriptor	DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases II subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11, ... (19 entities in total)
Functional Keywords	rna polymerase ii, rad26, cpd lesion, transcription-coupled dna repair, transcription, transcription-dna-rna complex, transcription/dna/rna
Biological source	Saccharomyces cerevisiae (baker's yeast) More
Total number of polymer chains	17
Total formula weight	681084.92
Authors	Sarsam, R.D.,Lahiri, I.,Leschziner, A.E. (deposition date: 2023-08-18, release date: 2024-01-24)
Primary citation	Sarsam, R.D.,Xu, J.,Lahiri, I.,Gong, W.,Li, Q.,Oh, J.,Zhou, Z.,Hou, P.,Chong, J.,Hao, N.,Li, S.,Wang, D.,Leschziner, A.E. Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121:e2314245121-e2314245121, 2024 Cited by PubMed: 38194460 DOI: 10.1073/pnas.2314245121 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation