8TVY
Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | DNA-directed RNA polymerase II subunit RPB1 | polymer | 1733 | 191821.6 | 1 | UniProt (P04050) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) | Saccharomyces cerevisiae (baker's yeast) | RNA polymerase II subunit 1,RNA polymerase II subunit B1,DNA-directed RNA polymerase III largest subunit,RNA polymerase II subunit B220 |
2 | B (B) | DNA-directed RNA polymerase subunit beta | polymer | 1224 | 138937.3 | 1 | UniProt (A0A6A5Q4H2) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) UniProt (by SIFTS) (P08518) | Saccharomyces cerevisiae (baker's yeast) | |
3 | C (C) | DNA-directed RNA polymerase II subunit RPB3 | polymer | 318 | 35330.5 | 1 | UniProt (A0A6A5Q0Z3) Pfam (PF01193) Pfam (PF01000) UniProt (by SIFTS) (P16370) | Saccharomyces cerevisiae (baker's yeast) | |
4 | D (D) | DNA-directed RNA polymerase II subunit RPB4 | polymer | 221 | 25451.2 | 1 | UniProt (A0A6A5PTI6) Pfam (PF03874) UniProt (by SIFTS) (P20433) | Saccharomyces cerevisiae (baker's yeast) | |
5 | E (E) | DNA-directed RNA polymerases I, II, and III subunit RPABC1 | polymer | 215 | 25117.1 | 1 | UniProt (A0A6A5Q456) Pfam (PF03871) Pfam (PF01191) UniProt (by SIFTS) (P20434) | Saccharomyces cerevisiae (baker's yeast) | |
6 | F (F) | DNA-directed RNA polymerases I, II, and III subunit RPABC2 | polymer | 155 | 17931.8 | 1 | UniProt (P20435) Pfam (PF01192) | Saccharomyces cerevisiae (baker's yeast) | |
7 | G (G) | DNA-directed RNA polymerase II subunit RPB7 | polymer | 171 | 19081.1 | 1 | UniProt (A0A6A5Q270) Pfam (PF03876) Pfam (PF00575) UniProt (by SIFTS) (P34087) | Saccharomyces cerevisiae (baker's yeast) | |
8 | H (H) | DNA-directed RNA polymerases I, II, and III subunit RPABC3 | polymer | 146 | 16525.4 | 1 | UniProt (A0A6A5Q8C2) Pfam (PF03870) UniProt (by SIFTS) (P20436) | Saccharomyces cerevisiae (baker's yeast) | |
9 | I (I) | DNA-directed RNA polymerase II subunit RPB9 | polymer | 122 | 14308.2 | 1 | UniProt (A0A7I9EWC2) Pfam (PF02150) Pfam (PF01096) UniProt (by SIFTS) (P27999) | Saccharomyces cerevisiae (baker's yeast) | |
10 | J (J) | DNA-directed RNA polymerases II subunit RPABC5 | polymer | 70 | 8290.7 | 1 | UniProt (A0A6A5Q7Q6) Pfam (PF01194) UniProt (by SIFTS) (P22139) | Saccharomyces cerevisiae (baker's yeast) | |
11 | K (K) | DNA-directed RNA polymerase II subunit RPB11 | polymer | 120 | 13633.5 | 1 | UniProt (A0A6A5Q7A1) Pfam (PF13656) UniProt (by SIFTS) (P38902) | Saccharomyces cerevisiae (baker's yeast) | |
12 | L (L) | DNA-directed RNA polymerases II subunit RPABC4 | polymer | 70 | 7730.0 | 1 | UniProt (A0A6A5PY05) Pfam (PF03604) UniProt (by SIFTS) (P40422) | Saccharomyces cerevisiae (baker's yeast) | |
13 | M (M) | RAD26 isoform 1 | polymer | 1085 | 124710.6 | 1 | UniProt (A0A8H4BZR7) Pfam (PF00176) Pfam (PF00271) UniProt (by SIFTS) (P40352) | Saccharomyces cerevisiae (baker's yeast) | |
14 | N (N) | DNA (NTS) | polymer | 47 | 14494.3 | 1 | synthetic construct | ||
15 | O (T) | DNA (TS) | polymer | 46 | 14275.1 | 1 | synthetic construct | ||
16 | P (R) | RNA | polymer | 10 | 3264.0 | 1 | synthetic construct | ||
17 | Q (O) | Transcription elongation factor 1 homolog | polymer | 85 | 9635.1 | 1 | UniProt (A0A6A5PV14) Pfam (PF05129) UniProt (by SIFTS) (P36053) | Saccharomyces cerevisiae (baker's yeast) | |
18 | R, S, U, V, W... (A, B, C, I, J...) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
19 | T (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 17 |
Total formula weight | 680537.3 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 547.6 | |
All* | Total formula weight | 681084.9 |