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8TVY

Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA-directed RNA polymerase II subunit RPB1polymer1733191821.61UniProt (P04050)
Pfam (PF04997)
Pfam (PF05001)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Pfam (PF04992)
Pfam (PF04990)
Saccharomyces cerevisiae (baker's yeast)RNA polymerase II subunit 1,RNA polymerase II subunit B1,DNA-directed RNA polymerase III largest subunit,RNA polymerase II subunit B220
2B
(B)
DNA-directed RNA polymerase subunit betapolymer1224138937.31UniProt (A0A6A5Q4H2)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF04566)
Pfam (PF04567)
Pfam (PF00562)
Pfam (PF04560)
UniProt (by SIFTS) (P08518)
Saccharomyces cerevisiae (baker's yeast)
3C
(C)
DNA-directed RNA polymerase II subunit RPB3polymer31835330.51UniProt (A0A6A5Q0Z3)
Pfam (PF01193)
Pfam (PF01000)
UniProt (by SIFTS) (P16370)
Saccharomyces cerevisiae (baker's yeast)
4D
(D)
DNA-directed RNA polymerase II subunit RPB4polymer22125451.21UniProt (A0A6A5PTI6)
Pfam (PF03874)
UniProt (by SIFTS) (P20433)
Saccharomyces cerevisiae (baker's yeast)
5E
(E)
DNA-directed RNA polymerases I, II, and III subunit RPABC1polymer21525117.11UniProt (A0A6A5Q456)
Pfam (PF03871)
Pfam (PF01191)
UniProt (by SIFTS) (P20434)
Saccharomyces cerevisiae (baker's yeast)
6F
(F)
DNA-directed RNA polymerases I, II, and III subunit RPABC2polymer15517931.81UniProt (P20435)
Pfam (PF01192)
Saccharomyces cerevisiae (baker's yeast)
7G
(G)
DNA-directed RNA polymerase II subunit RPB7polymer17119081.11UniProt (A0A6A5Q270)
Pfam (PF03876)
Pfam (PF00575)
UniProt (by SIFTS) (P34087)
Saccharomyces cerevisiae (baker's yeast)
8H
(H)
DNA-directed RNA polymerases I, II, and III subunit RPABC3polymer14616525.41UniProt (A0A6A5Q8C2)
Pfam (PF03870)
UniProt (by SIFTS) (P20436)
Saccharomyces cerevisiae (baker's yeast)
9I
(I)
DNA-directed RNA polymerase II subunit RPB9polymer12214308.21UniProt (A0A7I9EWC2)
Pfam (PF02150)
Pfam (PF01096)
UniProt (by SIFTS) (P27999)
Saccharomyces cerevisiae (baker's yeast)
10J
(J)
DNA-directed RNA polymerases II subunit RPABC5polymer708290.71UniProt (A0A6A5Q7Q6)
Pfam (PF01194)
UniProt (by SIFTS) (P22139)
Saccharomyces cerevisiae (baker's yeast)
11K
(K)
DNA-directed RNA polymerase II subunit RPB11polymer12013633.51UniProt (A0A6A5Q7A1)
Pfam (PF13656)
UniProt (by SIFTS) (P38902)
Saccharomyces cerevisiae (baker's yeast)
12L
(L)
DNA-directed RNA polymerases II subunit RPABC4polymer707730.01UniProt (A0A6A5PY05)
Pfam (PF03604)
UniProt (by SIFTS) (P40422)
Saccharomyces cerevisiae (baker's yeast)
13M
(M)
RAD26 isoform 1polymer1085124710.61UniProt (A0A8H4BZR7)
Pfam (PF00176)
Pfam (PF00271)
UniProt (by SIFTS) (P40352)
Saccharomyces cerevisiae (baker's yeast)
14N
(N)
DNA (NTS)polymer4714494.31synthetic construct
15O
(T)
DNA (TS)polymer4614275.11synthetic construct
16P
(R)
RNApolymer103264.01synthetic construct
17Q
(O)
Transcription elongation factor 1 homologpolymer859635.11UniProt (A0A6A5PV14)
Pfam (PF05129)
UniProt (by SIFTS) (P36053)
Saccharomyces cerevisiae (baker's yeast)
18R, S, U, V, W...
(A, B, C, I, J...)
ZINC IONnon-polymer65.48Chemie (ZN)
19T
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains17
Total formula weight680537.3
Non-Polymers*Number of molecules9
Total formula weight547.6
All*Total formula weight681084.9
*Water molecules are not included.

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PDB entries from 2024-11-06

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