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PDB: 243 件

1MBC
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X-RAY STRUCTURE AND REFINEMENT OF CARBON-MONOXY (FE II)-MYOGLOBIN AT 1.5 ANGSTROMS RESOLUTION
分子名称: CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Kuriyan, J, Petsko, G.A.
登録日1988-09-15
公開日1989-01-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献X-ray structure and refinement of carbon-monoxy (Fe II)-myoglobin at 1.5 A resolution.
J.Mol.Biol., 192, 1986
2MA2
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Solution structure of RasGRP2 EF hands bound to calcium
分子名称: RAS guanyl-releasing protein 2
著者Kuriyan, J, Iwig, J, Vercoulen, Y, Das, R, Barros, T, Limnander, A, Che, Y, Pelton, J, Wemmer, D, Roose, J.
登録日2013-06-24
公開日2013-08-21
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1.
Elife, 2, 2013
2TPR
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BU of 2tpr by Molmil
X-RAY STRUCTURE OF TRYPANOTHIONE REDUCTASE FROM CRITHIDIA FASCICULATA AT 2.4 ANGSTROMS RESOLUTION
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, TRYPANOTHIONE REDUCTASE
著者Kuriyan, J, Kong, X.-P, Krishna, T.S.R.
登録日1991-08-22
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献X-ray structure of trypanothione reductase from Crithidia fasciculata at 2.4-A resolution.
Proc.Natl.Acad.Sci.USA, 88, 1991
1A06
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CALMODULIN-DEPENDENT PROTEIN KINASE FROM RAT
分子名称: CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE
著者Kuriyan, J, Goldberg, J.
登録日1997-12-09
公開日1998-04-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I.
Cell(Cambridge,Mass.), 84, 1996
3KK9
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CaMKII Substrate Complex B
分子名称: Calcium/calmodulin dependent protein kinase II
著者Kuriyan, J, Chao, L.H, Pellicena, P, Deindl, S, Barclay, L.A, Schulman, H.
登録日2009-11-04
公開日2010-02-09
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (3.206 Å)
主引用文献Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation.
Nat.Struct.Mol.Biol., 17, 2010
3KK8
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CaMKII Substrate Complex A
分子名称: Calcium/calmodulin dependent protein kinase II, MAGNESIUM ION
著者Kuriyan, J, Chao, L.H, Pellicena, P, Deindl, S, Barclay, L.A, Schulman, H.
登録日2009-11-04
公開日2010-02-09
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation.
Nat.Struct.Mol.Biol., 17, 2010
3KL8
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CaMKIINtide Inhibitor Complex
分子名称: Calcium/calmodulin dependent protein kinase II, Calcium/calmodulin-dependent protein kinase II inhibitor 1
著者Kuriyan, J, Chao, L.H, Pellicena, P, Deindl, S, Barclay, L.A, Schulman, H.
登録日2009-11-06
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.372 Å)
主引用文献Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation.
Nat.Struct.Mol.Biol., 17, 2010
7WJ3
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Crystal structure of HLA-C*1402 complexed with 4-mer lipopeptide
分子名称: 1,2-ETHANEDIOL, 4-mer lipopeptide, Beta-2-microglobulin, ...
著者Kuroha, J, Morita, D, Asa, M, Sugita, M.
登録日2022-01-05
公開日2022-06-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.56343615 Å)
主引用文献Crystal structures of N-myristoylated lipopeptide-bound HLA class I complexes indicate reorganization of B-pocket architecture upon ligand binding.
J.Biol.Chem., 298, 2022
7WJ2
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Crystal structure of HLA-C*1402 complexed with 8-mer HIV gag peptide
分子名称: 1,2-ETHANEDIOL, 8-mer peptide, ACETATE ION, ...
著者Kuroha, J, Morita, D, Asa, M, Sugita, M.
登録日2022-01-05
公開日2022-06-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Crystal structures of N-myristoylated lipopeptide-bound HLA class I complexes indicate reorganization of B-pocket architecture upon ligand binding.
J.Biol.Chem., 298, 2022
1BF5
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TYROSINE PHOSPHORYLATED STAT-1/DNA COMPLEX
分子名称: DNA (5'-D(*AP*CP*AP*GP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*G P*C)-3'), DNA (5'-D(*TP*GP*CP*AP*TP*TP*TP*AP*CP*GP*GP*GP*AP*AP*AP*CP*T P*G)-3'), SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA/BETA
著者Kuriyan, J, Zhao, Y, Chen, X, Vinkemeier, U, Jeruzalmi, D, Darnell Jr, J.E.
登録日1998-05-27
公開日1998-08-12
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA.
Cell(Cambridge,Mass.), 93, 1998
1J3C
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Solution structure of the C-terminal domain of the HMGB2
分子名称: High mobility group protein 2
著者Kurita, J, Shimahara, H, Yoshida, M, Tate, S.
登録日2003-01-23
公開日2004-05-25
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Strucutral comparison of two HMG-boxes in the non-histone protein HMG-2 with in the HMG-1
To be Published
1J3X
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Solution structure of the N-terminal domain of the HMGB2
分子名称: High mobility group protein 2
著者Kurita, J, Shimahara, H, Yoshida, M, Tate, S.
登録日2003-02-19
公開日2004-06-29
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Strucutral comparison of two HMG-boxes in the non-histone protein HMG-2 with in the HMG-1
To be Published
1J3D
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Solution structure of the C-terminal domain of the HMGB2
分子名称: High mobility group protein 2
著者Kurita, J, Shimahara, H, Yoshida, M, Tate, S.
登録日2003-01-23
公開日2004-05-25
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Strucutral comparison of two HMG-boxes in the non-histone protein HMG-2 with in the HMG-1
To be Published
1TRB
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BU of 1trb by Molmil
CONVERGENT EVOLUTION OF SIMILAR FUNCTION IN TWO STRUCTURALLY DIVERGENT ENZYMES
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, THIOREDOXIN REDUCTASE
著者Kuriyan, J, Krishna, T.S.R.
登録日1991-09-07
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Convergent evolution of similar function in two structurally divergent enzymes.
Nature, 352, 1991
5Y95
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Haddock model of mSIN3B PAH1 domain
分子名称: Paired amphipathic helix protein Sin3b, propan-2-yl (3R,6S,9aS)-3-ethyl-8-(3-methylbutyl)-6-(2-methylsulfanylethyl)-4,7-bis(oxidanylidene)-9,9a-dihydro-6H-pyrazino[2,1-c][1,2,4]oxadiazine-1-carboxylate
著者Kurita, J, Hirao, Y, Nishimura, Y.
登録日2017-08-22
公開日2017-10-04
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A mimetic of the mSin3-binding helix of NRSF/REST ameliorates abnormal pain behavior in chronic pain models.
Bioorg. Med. Chem. Lett., 27, 2017
4GS3
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Dimeric structure of the N-terminal domain of PriB protein from Thermoanaerobacter tencongensis solved ab initio
分子名称: Single-stranded DNA-binding protein
著者Liebschner, D, Brzezinski, K, Dauter, M, Dauter, Z, Nowak, M, Kur, J, Olszewski, M.
登録日2012-08-27
公開日2012-09-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.09 Å)
主引用文献Dimeric structure of the N-terminal domain of PriB protein from Thermoanaerobacter tengcongensis solved ab initio.
Acta Crystallogr.,Sect.D, 68, 2012
3HP4
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BU of 3hp4 by Molmil
Crystal structure of psychrotrophic esterase EstA from Pseudoalteromonas sp. 643A inhibited by monoethylphosphonate
分子名称: GDSL-esterase
著者Brzuszkiewicz, A, Nowak, E, Dauter, Z, Dauter, M, Cieslinski, H, Kur, J.
登録日2009-06-03
公開日2009-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure of EstA esterase from psychrotrophic Pseudoalteromonas sp. 643A covalently inhibited by monoethylphosphonate.
Acta Crystallogr.,Sect.F, 65, 2009
2AXW
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Structure of DraD invasin from uropathogenic Escherichia coli
分子名称: CHLORIDE ION, DraD invasin, GLYCEROL
著者Jedrzejczak, R, Dauter, Z, Dauter, M, Piatek, R, Zalewska, B, Mroz, M, Bury, K, Nowicki, B, Kur, J.
登録日2005-09-06
公開日2005-11-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Structure of DraD invasin from uropathogenic Escherichia coli: a dimer with swapped beta-tails.
Acta Crystallogr.,Sect.D, 62, 2006
1EH4
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BINARY COMPLEX OF CASEIN KINASE-1 FROM S. POMBE WITH AN ATP COMPETITIVE INHIBITOR, IC261
分子名称: 3-[(2,4,6-TRIMETHOXY-PHENYL)-METHYLENE]-INDOLIN-2-ONE, CASEIN KINASE-1, SULFATE ION
著者Mashhoon, N, Demaggio, A.J, Tereshko, V, Bergmeier, S.C, Egli, M, Hoekstra, M.F, Kuret, J.
登録日2000-02-18
公開日2001-09-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of a Conformation-Selective Casein Kinase-1 Inhibitor
J.Biol.Chem., 275, 2000
7SA7
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Crystal structure of the apo SH2 domains of Syk
分子名称: Tyrosine-protein kinase SYK
著者Hobbs, H.T, Badroos, J, Gee, C.L, Kuriyan, J.
登録日2021-09-22
公開日2021-10-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Differences in the dynamics of the tandem-SH2 modules of the Syk and ZAP-70 tyrosine kinases.
Protein Sci., 30, 2021
1EQN
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E.COLI PRIMASE CATALYTIC CORE
分子名称: DNA PRIMASE
著者Podobnik, M, McInerney, P, O'Donnell, M, Kuriyan, J.
登録日2000-04-05
公開日2000-06-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A TOPRIM domain in the crystal structure of the catalytic core of Escherichia coli primase confirms a structural link to DNA topoisomerases.
J.Mol.Biol., 300, 2000
2GS6
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Crystal Structure of the active EGFR kinase domain in complex with an ATP analog-peptide conjugate
分子名称: CHLORIDE ION, Epidermal growth factor receptor, Peptide, ...
著者Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J.
登録日2006-04-25
公開日2006-06-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
Cell(Cambridge,Mass.), 125, 2006
2RF9
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Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide
分子名称: ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor
著者Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J.
登録日2007-09-28
公開日2007-12-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
Nature, 450, 2007
2RFE
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Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide
分子名称: ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor
著者Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J.
登録日2007-09-28
公開日2007-12-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
Nature, 450, 2007
5WDO
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H-Ras bound to GMP-PNP at 277K
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Cofsky, J.C, Bandaru, P, Gee, C.L, Kuriyan, J.
登録日2017-07-05
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Deconstruction of the Ras switching cycle through saturation mutagenesis.
Elife, 6, 2017

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