1EH4

BINARY COMPLEX OF CASEIN KINASE-1 FROM S. POMBE WITH AN ATP COMPETITIVE INHIBITOR, IC261

Summary for 1EH4

• Entry DOI: 10.2210/pdb1eh4/pdb
• Related: 1CSN 2CSN
• Descriptor: CASEIN KINASE-1, SULFATE ION, 3-[(2,4,6-TRIMETHOXY-PHENYL)-METHYLENE]-INDOLIN-2-ONE, ... (4 entities in total)
• Functional Keywords: protein kinase, casein kinase-1, protein-inhibitor binary complex, transferase
• Biological source: Schizosaccharomyces pombe (fission yeast)
• Cellular location: Cytoplasm: P40233
• Total number of polymer chains: 2
• Total formula weight: 70433.83

Authors

Mashhoon, N.,Demaggio, A.J.,Tereshko, V.,Bergmeier, S.C.,Egli, M.,Hoekstra, M.F.,Kuret, J. (deposition date: 2000-02-18, release date: 2001-09-19, Last modification date: 2024-03-13)

• Primary citation: Mashhoon, N.,Demaggio, A.J.,Tereshko, V.,Bergmeier, S.C.,Egli, M.,Hoekstra, M.F.,Kuret, J.; Crystal Structure of a Conformation-Selective Casein Kinase-1 Inhibitor; J.Biol.Chem., 275:20052-20060, 2000; PubMed: 10749871; DOI: 10.1074/jbc.M001713200

Experimental method

X-RAY DIFFRACTION (2.8 Å)