7N6A
 
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6W2U
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6W09
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6W1C
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6VYV
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5U4W
 | | Cryo-EM Structure of Immature Zika Virus | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein, ... | | Authors: | Mangala Prasad, V, Miller, A.S, Klose, T, Sirohi, D, Buda, G, Jiang, W, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2016-12-06 | | Release date: | 2017-01-11 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (9.1 Å) | | Cite: | Structure of the immature Zika virus at 9 angstrom resolution.
Nat. Struct. Mol. Biol., 24, 2017
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6WDT
 | | Enterovirus D68 in complex with human monoclonal antibody EV68-228 | | Descriptor: | EV68-228 heavy chain, EV68-228 light chain, viral protein 1, ... | | Authors: | Fu, J, Vogt, M.R, Klose, T, Crowe, J.E, Rossmann, M.G, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2020-04-01 | | Release date: | 2020-07-15 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease.
Sci Immunol, 5, 2020
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7TAH
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7T9P
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7TAJ
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7TAF
 | | Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain virion in complex with inhibitor 11526092 | | Descriptor: | N,N-dimethyl-5-(3-{2-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenoxy}propyl)-1,2-oxazole-3-carboxamide, viral protein 1, viral protein 2, ... | | Authors: | Fu, J, Klose, T, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-12-20 | | Release date: | 2023-01-25 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2 Å) | | Cite: | Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68
To Be Published
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7TAG
 | | Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain virion in complex with pleconaril | | Descriptor: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, viral protein 1, viral protein 2, ... | | Authors: | Fu, J, Klose, T, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-12-20 | | Release date: | 2023-01-25 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68
To Be Published
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6WDS
 | | Enterovirus D68 in complex with human monoclonal antibody EV68-159 | | Descriptor: | EV68-159 heavy chain, EV68-159 light chain, viral protein 1, ... | | Authors: | Fu, J, Klose, T, Vogt, M.R, Crowe, J.E, Rossmann, M.G, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2020-04-01 | | Release date: | 2020-07-15 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease.
Sci Immunol, 5, 2020
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5UHY
 | | A Human Antibody Against Zika Virus Crosslinks the E Protein to Prevent Infection | | Descriptor: | ZV67 Fab chain 1, ZV67 Fab chain 2, envelope protein | | Authors: | Hasan, S.S, Miller, A, Sapparapu, G, Fernandez, E, Klose, T, Long, F, Fokine, A, Porta, J.C, Jiang, W, Diamond, M.S, Crowe Jr, J.E, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2017-01-12 | | Release date: | 2017-03-29 | | Last modified: | 2019-11-27 | | Method: | ELECTRON MICROSCOPY (6.2 Å) | | Cite: | A human antibody against Zika virus crosslinks the E protein to prevent infection.
Nat Commun, 8, 2017
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4C0Y
 | | Cryo-EM reconstruction of empty enterovirus 71 in complex with a neutralizing antibody E18 | | Descriptor: | FAB EV18 4 D6-1 F1 G9, VP1, VP2, ... | | Authors: | Plevka, P, Perera, R, Cardosa, J, Suksatu, A, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2013-08-08 | | Release date: | 2014-02-05 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (16 Å) | | Cite: | Neutralizing Antibodies Can Initiate Genome Release from Human Enterovirus 71.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4C10
 | | Cryo-EM reconstruction of empty enterovirus 71 in complex with a neutralizing antibody E19 | | Descriptor: | CHLORIDE ION, EV19 5 C1-6 F1 C11, SODIUM ION, ... | | Authors: | Plevka, P, Perera, R, Cardosa, J, Suksatu, A, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2013-08-08 | | Release date: | 2014-02-05 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (13 Å) | | Cite: | Neutralizing Antibodies Can Initiate Genome Release from Human Enterovirus 71.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4C0U
 | | Cryo-EM reconstruction of enterovirus 71 in complex with a neutralizing antibody E18 | | Descriptor: | FAB EV18 4 D6-1 F1 G9, VP1, VP2, ... | | Authors: | Plevka, P, Perera, R, Cardosa, J, Suksatu, A, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2013-08-08 | | Release date: | 2014-02-05 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (10 Å) | | Cite: | Neutralizing Antibodies Can Initiate Genome Release from Human Enterovirus 71.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4AED
 | | Crystal structure of Human enterovirus 71 | | Descriptor: | CALCIUM ION, LAURIC ACID, VP1, ... | | Authors: | Plevka, P, Perera, R, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2012-01-09 | | Release date: | 2012-04-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Crystal Structure of Human Enterovirus 71.
Science, 336, 2012
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2B6B
 | | Cryo EM structure of Dengue complexed with CRD of DC-SIGN | | Descriptor: | CD209 antigen, envelope glycoprotein | | Authors: | Pokidysheva, E, Zhang, Y, Battisti, A.J, Bator-Kelly, C.M, Chipman, P.R, Gregorio, G, Hendrickson, W.A, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2005-09-30 | | Release date: | 2006-03-07 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (25 Å) | | Cite: | Cryo-EM reconstruction of dengue virus in complex with the carbohydrate recognition domain of DC-SIGN
Cell(Cambridge,Mass.), 124, 2006
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4UOM
 | | Electron Cryo-microscopy of Venezuelan Equine Encephalitis Virus TC- 83 in complex with neutralizing antibody Fab F5 | | Descriptor: | FAB FRAGMENT HEAVY CHAIN, FAB FRAGMENT LIGHT CHAIN | | Authors: | Porta, J, Jose, J, Roehrig, J.T, Blair, C.D, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2014-06-05 | | Release date: | 2014-10-15 | | Last modified: | 2017-08-23 | | Method: | ELECTRON MICROSCOPY (17 Å) | | Cite: | Locking and Blocking the Viral Landscape of an Alphavirus with Neutralizing Antibodies.
J.Virol., 88, 2014
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4UOK
 | | Electron Cryo-microscopy of Venezuelan Equine Encephalitis Virus TC-83 in complex with neutralizing antibody Fab 3B4C-4 | | Descriptor: | FAB FRAGMENT HEAVY CHAIN, FAB FRAGMENT LIGHT CHAIN | | Authors: | Porta, J, Jose, J, Roehrig, J.T, Blair, C.D, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2014-06-04 | | Release date: | 2014-09-17 | | Last modified: | 2019-05-29 | | Method: | ELECTRON MICROSCOPY (18 Å) | | Cite: | Locking and blocking the viral landscape of an alphavirus with neutralizing antibodies.
J.Virol., 88, 2014
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5IRE
 | | The cryo-EM structure of Zika Virus | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein | | Authors: | Sirohi, D, Chen, Z, Sun, L, Klose, T, Pierson, T, Rossmann, M, Kuhn, R. | | Deposit date: | 2016-03-13 | | Release date: | 2016-03-30 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The 3.8 angstrom resolution cryo-EM structure of Zika virus.
Science, 352, 2016
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4WM7
 | | Crystal Structure of Human Enterovirus D68 in Complex with Pleconaril | | Descriptor: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, VP1, VP2, ... | | Authors: | Liu, Y, Sheng, J, Fokine, A, Meng, G, Long, F, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2014-10-08 | | Release date: | 2015-01-14 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Science, 347, 2015
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4WM8
 | | Crystal Structure of Human Enterovirus D68 | | Descriptor: | DECANOIC ACID, VP1, VP2, ... | | Authors: | Liu, Y, Sheng, J, Fokine, A, Meng, G, Long, F, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2014-10-08 | | Release date: | 2015-01-14 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Science, 347, 2015
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3IYA
 | | Association of the pr peptides with dengue virus blocks membrane fusion at acidic pH | | Descriptor: | Envelope protein, prM protein | | Authors: | Yu, I, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Rossmann, M.G, Chen, J. | | Deposit date: | 2009-06-01 | | Release date: | 2010-04-14 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (22 Å) | | Cite: | Association of the pr peptides with dengue virus at acidic pH blocks membrane fusion.
J.Virol., 83, 2009
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