7TAJ

Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain in complex with inhibitor 11526093 (no/low occupancy-no inhibitor modeled)

Summary for 7TAJ

• Entry DOI: 10.2210/pdb7taj/pdb
• EMDB information: 25776
• Descriptor: viral protein 1, viral protein 3, viral protein 2, ... (4 entities in total)
• Functional Keywords: virus, ev-d68, acute flaccid myelitis, afm, inhibitor, antivirial, structural genomics, center for structural genomics of infectious diseases, csgid
• Biological source: enterovirus D68; More
• Total number of polymer chains: 4
• Total formula weight: 93842.08

Authors

Fu, J.,Klose, T.,Kuhn, R.J.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2021-12-20, release date: 2023-01-25)

• Primary citation: Lane, T.,Fu, J.,Sherry, B.,Tarbet, B.,Hurst, B.L.,Riabova, O.,Kazakova, E.,Egorova, A.,Clarke, P.,Leser, S.,Frost, J.,Rudy, M.,Tyler, K.,Klose, T.,Kuhn, R.J.,Makarov, V.,Ekins, S.; Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2 Å)