1EWZ
 
 | | CRYSTAL STRUCTURE OF THE OXA-10 BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA | | 分子名称: | BETA LACTAMASE OXA-10 | | 著者 | Golemi, D, Maveyraud, L, Vakulenko, S, Tranier, S, Ishiwata, A, Kotra, L.P, Samama, J.P, Mobashery, S. | | 登録日 | 2000-04-28 | | 公開日 | 2000-11-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The First Structural and Mechanistic Insights for Class D beta-Lactamases: Evidence for a Novel Catalytic Process for Turnover of beta-Lactam Antibiotics
J.Am.Chem.Soc., 122, 2000
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3MO7
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2E6Y
 | | Covalent complex of orotidine 5'-monophosphate decarboxylase (ODCase) with 6-Iodo-UMP | | 分子名称: | GLYCEROL, Orotidine 5'-phosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE | | 著者 | Fujihashi, M, Bello, A.M, Kotra, L.P, Pai, E.F. | | 登録日 | 2007-01-05 | | 公開日 | 2007-02-27 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A Potent, Covalent Inhibitor of Orotidine 5'-Monophosphate Decarboxylase with Antimalarial Activity.
J.Med.Chem., 50, 2007
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1BT5
 | | CRYSTAL STRUCTURE OF THE IMIPENEM INHIBITED TEM-1 BETA-LACTAMASE FROM ESCHERICHIA COLI | | 分子名称: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, PROTEIN (BETA-LACTAMASE), SULFATE ION | | 著者 | Maveyraud, L, Mourey, L, Pedelacq, J.D, Guillet, V, Kotra, L.K, Mobashery, S, Samama, J.P. | | 登録日 | 1998-09-02 | | 公開日 | 1999-09-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Basis for Clinical Longevity of Carbapenem Antibiotics in the Face of Challenge by the Common Class A Beta-Lactamases from Antibiotic-Resistant Bacteria
J.Am.Chem.Soc., 120, 1998
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1X1Z
 | | Orotidine 5'-monophosphate decarboxylase (odcase) complexed with BMP (produced from 6-cyanoump) | | 分子名称: | 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase | | 著者 | Fujihashi, M, Bello, A.M, Poduch, E, Wei, L, Annedi, S.C, Pai, E.F, Kotra, L.P. | | 登録日 | 2005-04-15 | | 公開日 | 2005-12-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | An unprecedented twist to ODCase catalytic activity
J.Am.Chem.Soc., 127, 2005
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2Q8Z
 | | Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase complexed with 6-amino-UMP | | 分子名称: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 6-AMINOURIDINE 5'-MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Liu, Y, Lau, W, Bello, A.M, Kotra, L.P, Hui, R, Pai, E.F. | | 登録日 | 2007-06-12 | | 公開日 | 2008-01-29 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-Activity Relationships of C6-Uridine Derivatives Targeting Plasmodia Orotidine Monophosphate Decarboxylase.
J.Med.Chem., 51, 2008
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2QAF
 | | Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase covalently modified by 6-iodo-UMP | | 分子名称: | Orotidine 5' monophosphate decarboxylase, SULFATE ION, URIDINE-5'-MONOPHOSPHATE | | 著者 | Liu, Y, Lau, W, Bello, A.M, Kotra, L.P, Hui, R, Pai, E.F. | | 登録日 | 2007-06-15 | | 公開日 | 2008-04-29 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylase
J.Med.Chem., 51, 2008
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3G3D
 | | Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 5-fluoro-6-azido-UMP | | 分子名称: | 5-FLUORO-URIDINE-5'-MONOPHOSPHATE, GLYCEROL, SULFATE ION, ... | | 著者 | Liu, Y, Tang, H.L, Bello, A, Poduch, E, Kotra, L, Pai, E. | | 登録日 | 2009-02-02 | | 公開日 | 2009-03-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents.
J.Med.Chem., 52, 2009
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2GUU
 | | crystal structure of Plasmodium vivax orotidine 5-monophosphate decarboxylase with 6-aza-UMP bound | | 分子名称: | 6-AZA URIDINE 5'-MONOPHOSPHATE, ODcase | | 著者 | Dong, A, Lew, J, Zhao, Y, Sundararajan, E, Wasney, G, Vedadi, M, Koeieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Pai, E.F, Kotra, L, Bochkarev, A, Hui, R, Amani, M, Structural Genomics Consortium (SGC) | | 登録日 | 2006-05-01 | | 公開日 | 2006-05-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Crystal structure of Plasmodium vivax orotidine 5-monophosphate decarboxylase with 6-aza-UMP bound
To be Published
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1E3U
 | | MAD structure of OXA10 class D beta-lactamase | | 分子名称: | 1,2-ETHANEDIOL, BETA-LACTAMASE OXA-10, GOLD (I) CYANIDE ION, ... | | 著者 | Maveyraud, L, Golemi, D, Kotra, L.P, Tranier, S, Vakulenko, S, Mobashery, S, Samama, J.P. | | 登録日 | 2000-06-23 | | 公開日 | 2001-01-12 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Insights Into Class D Beta-Lactamases are Revealed by the Crystal Structure of the Oxa10 Enzyme from Pseudomonas Aeruginosa
Structure, 8, 2000
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1E4D
 | | Structure of OXA10 beta-lactamase at pH 8.3 | | 分子名称: | 1,2-ETHANEDIOL, BETA-LACTAMASE OXA-10, SULFATE ION | | 著者 | Maveyraud, L, Golemi, D, Kotra, L.P, Tranier, S, Vakulenko, S, Mobashery, S, Samama, J.P. | | 登録日 | 2000-07-03 | | 公開日 | 2001-01-12 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Insights Into Class D Beta-Lactamases are Revealed by the Crystal Structure of the Oxa10 Enzyme from Pseudomonas Aeruginosa
Structure, 8, 2000
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4HKP
 | | Crystal structure of human orotidine 5'-monophosphate decarboxylase complexed with CMP-N3-oxide | | 分子名称: | 5-hydroxycytidine 5'-(dihydrogen phosphate), GLYCEROL, N-hydroxycytidine 5'-(dihydrogen phosphate), ... | | 著者 | To, T.K, Kotra, L.P, Pai, E.F. | | 登録日 | 2012-10-15 | | 公開日 | 2012-11-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Novel cytidine-based orotidine-5'-monophosphate decarboxylase inhibitors with an unusual twist.
J.Med.Chem., 55, 2012
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3G3M
 | | Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 5-fluoro-6-iodo-UMP | | 分子名称: | 5-FLUORO-URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase | | 著者 | Liu, Y, Tang, H.L, Bello, A.M, Poduch, E, Kotra, L.P, Pai, E.F. | | 登録日 | 2009-02-02 | | 公開日 | 2009-03-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents.
J.Med.Chem., 52, 2009
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4HIB
 | | Crystal structure of human orotidine 5'-monophosphate decarboxylase complexed with CMP-N4-OH | | 分子名称: | CHLORIDE ION, GLYCEROL, N-hydroxycytidine 5'-(dihydrogen phosphate), ... | | 著者 | To, T.K, Kotra, L.P, Pai, E.F. | | 登録日 | 2012-10-11 | | 公開日 | 2012-11-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Novel cytidine-based orotidine-5'-monophosphate decarboxylase inhibitors with an unusual twist.
J.Med.Chem., 55, 2012
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3SEC
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3DBP
 | | Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Complexed with 6-NH2-UMP | | 分子名称: | 6-AMINOURIDINE 5'-MONOPHOSPHATE, Orotidine 5'-phosphate decarboxylase, SULFATE ION | | 著者 | Liu, Y, To, T, Bello, A.M, Kotra, L.P, Pai, E.F. | | 登録日 | 2008-06-02 | | 公開日 | 2009-06-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Complexed with 6-NH2-UMP
To be Published
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3S9Y
 | | Crystal Structure of P. falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP in space group P21, produced from 5-fluoro-6-azido-UMP | | 分子名称: | 6-amino-5-fluorouridine 5'-(dihydrogen phosphate), DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, ... | | 著者 | Liu, Y, Kotra, L.P, Pai, E.F. | | 登録日 | 2011-06-02 | | 公開日 | 2012-04-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents.
J.Med.Chem., 52, 2009
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3MI2
 | | Crystal structure of human orotidine-5'-monophosphate decarboxylase complexed with pyrazofurin monophosphate | | 分子名称: | (1S)-1,4-anhydro-1-(5-carbamoyl-4-hydroxy-1H-pyrazol-3-yl)-5-O-phosphono-D-ribitol, Uridine 5'-monophosphate synthase | | 著者 | Liu, Y, To, T, Kotra, L.P, Pai, E.F. | | 登録日 | 2010-04-09 | | 公開日 | 2010-05-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structural determinants for the inhibitory ligands of orotidine-5'-monophosphate decarboxylase.
Bioorg.Med.Chem., 18, 2010
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3N3M
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3BGJ
 | | Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 6-iodo-UMP | | 分子名称: | GLYCEROL, URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase | | 著者 | Liu, Y, Tang, H.L, Bello, A.M, Devalla, S, Kotra, L.P, Pai, E.F. | | 登録日 | 2007-11-26 | | 公開日 | 2008-11-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 6-iodo-UMP
To be Published
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3BGG
 | | Crystal structure of Human Orotidine 5'-monophosphate Decarboxylase complexed with BMP | | 分子名称: | 6-HYDROXYURIDINE-5'-PHOSPHATE, Uridine 5'-monophosphate synthase | | 著者 | Liu, Y, Tang, H.L, Wang, X.Y, Kotra, L.P, Pai, E.F. | | 登録日 | 2007-11-26 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Crystal structure of Human Orotidine 5'-monophosphate Decarboxylase complexed with BMP
To be Published
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3BK0
 | | Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Complexed with 5-CN-UMP | | 分子名称: | 5-CYANO-URIDINE-5'-MONOPHOSPHATE, GLYCEROL, SULFATE ION, ... | | 著者 | Liu, Y, Tang, H.L, Avina, M.E.M, Kotra, L.P, Pai, E.F. | | 登録日 | 2007-12-05 | | 公開日 | 2008-11-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Complexed with 5-CN-UMP
To be Published
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3BAR
 | | Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase covalently modified by 6-azido-UMP | | 分子名称: | Orotidine 5'-phosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE | | 著者 | Liu, Y, Bello, A.M, Poduch, E, Lau, W, Kotra, L.P, Pai, E.F. | | 登録日 | 2007-11-08 | | 公開日 | 2008-01-29 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-Activity Relationships of C6-Uridine Derivatives Targeting Plasmodia Orotidine Monophosphate Decarboxylase.
J.Med.Chem., 51, 2008
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3MW7
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3N2M
 | | Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-amino-5-fluorouridine 5'-(dihydrogen phosphate), ... | | 著者 | Liu, Y, Kotra, L.P, Pai, E.F. | | 登録日 | 2010-05-18 | | 公開日 | 2011-04-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP
To be Published
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