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PDB: 16 件
3HRR
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The Product Template Domain from PksA with Harris Compound Bound
分子名称: 1-(3-acetyl-4,5-dihydroxy-7-methoxynaphthalen-2-yl)propan-2-one, Aflatoxin biosynthesis polyketide synthase
著者Korman, T.P, Tsai, S.C.
登録日2009-06-09
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization.
Nature, 461, 2009
3HRQ
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The Product Template Domain from PksA with palmitate bound
分子名称: Aflatoxin biosynthesis polyketide synthase, PALMITIC ACID
著者Korman, T.P, Tsai, S.C.
登録日2009-06-09
公開日2009-10-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization.
Nature, 461, 2009
1X7G
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Actinorhodin Polyketide Ketoreductase, act KR, with NADP bound
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative ketoacyl reductase
著者Korman, T.P, Hill, J.A, Vu, T.N.
登録日2004-08-13
公開日2004-12-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity
Biochemistry, 43, 2004
1X7H
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Actinorhodin Polyketide Ketoreductase, with NADPH bound
分子名称: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative ketoacyl reductase
著者Korman, T.P, Hill, J.A, Vu, T.N.
登録日2004-08-13
公開日2004-12-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity
Biochemistry, 43, 2004
3ILS
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The Thioesterase Domain from PksA
分子名称: Aflatoxin biosynthesis polyketide synthase
著者Korman, T.P.
登録日2009-08-07
公開日2010-04-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and function of an iterative polyketide synthase thioesterase domain catalyzing Claisen cyclization in aflatoxin biosynthesis.
Proc.Natl.Acad.Sci.USA, 107, 2010
1XR3
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Actinorhodin Polyketide Ketoreductase with NADP and the Inhibitor Isoniazid bound
分子名称: 4-(DIAZENYLCARBONYL)PYRIDINE, ACTINORHODIN POLYKETIDE KETOREDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Korman, T.P, Hill, J.A, Vu, T.N, Tsai, S.C.
登録日2004-10-13
公開日2005-09-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity.
Biochemistry, 43, 2004
4GXN
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Diethylphosphonate Inhibited Structure of the Proteus mirabilis Lipase
分子名称: CALCIUM ION, DIETHYL PHOSPHONATE, Putative lipase, ...
著者Korman, T.P, Bowie, J.U.
登録日2012-09-04
公開日2013-02-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of Proteus mirabilis Lipase, a Novel Lipase from the Proteus/Psychrophilic Subfamily of Lipase Family I.1.
Plos One, 7, 2012
4GW3
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Crystal Structure of the Lipase from Proteus mirabilis
分子名称: CALCIUM ION, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Korman, T.P.
登録日2012-08-31
公開日2013-02-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Proteus mirabilis Lipase, a Novel Lipase from the Proteus/Psychrophilic Subfamily of Lipase Family I.1.
Plos One, 7, 2012
4HS9
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Methanol tolerant mutant of the Proteus mirabilis lipase
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CALCIUM ION, CHLORIDE ION, ...
著者Korman, T.P.
登録日2012-10-29
公開日2013-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dieselzymes: development of a stable and methanol tolerant lipase for biodiesel production by directed evolution.
Biotechnol Biofuels, 6, 2013
3QRW
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Actinorhodin Polyketide Ketoreductase Mutant P94L bound to NADPH
分子名称: FORMIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ketoacyl reductase
著者Korman, T.P, Javidpour, P, Tsai, S.-C.
登録日2011-02-18
公開日2011-05-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.792 Å)
主引用文献Structural and Biochemical Analyses of Regio- and Stereospecificities Observed in a Type II Polyketide Ketoreductase.
Biochemistry, 50, 2011
2RH4
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Actinorhodin ketoreductase, actKR, with NADPH and Inhibitor Emodin
分子名称: 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, Actinorhodin Polyketide Ketoreductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Korman, T.P, Tsai, S.-C.
登録日2007-10-05
公開日2008-08-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Inhibition kinetics and emodin cocrystal structure of a type II polyketide ketoreductase
Biochemistry, 47, 2008
2RHC
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Actinorhodin ketordeuctase, actKR, with NADP+ and Inhibitor Emodin
分子名称: 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, Actinorhodin Polyketide Ketoreductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Korman, T.P, Tsai, S.-C.
登録日2007-10-08
公開日2008-08-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Inhibition kinetics and emodin cocrystal structure of a type II polyketide ketoreductase
Biochemistry, 47, 2008
2RHR
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P94L actinorhodin ketordeuctase mutant, with NADPH and Inhibitor Emodin
分子名称: 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, Actinorhodin Polyketide Ketoreductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Korman, T.P, Tsai, S.-C.
登録日2007-10-09
公開日2008-08-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Inhibition kinetics and emodin cocrystal structure of a type II polyketide ketoreductase
Biochemistry, 47, 2008
6VGS
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Alpha-ketoisovalerate decarboxylase (KivD) from Lactococcus lactis, thermostable mutant
分子名称: Alpha-keto acid decarboxylase, MAGNESIUM ION, THIAMINE DIPHOSPHATE
著者Chan, S, Korman, T.P, Sawaya, M.R, Bowie, J.U.
登録日2020-01-08
公開日2020-08-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Isobutanol production freed from biological limits using synthetic biochemistry.
Nat Commun, 11, 2020
3NI3
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54-Membered ring macrocyclic beta-sheet peptide
分子名称: 54-membered ring macrocyclic beta-sheet peptide, ISOPROPYL ALCOHOL
著者Sawaya, M.R, Eisenberg, D, Nowick, J.S, Korman, T.P, Khakshoor, O.
登録日2010-06-15
公開日2010-09-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献X-ray crystallographic structure of an artificial beta-sheet dimer.
J.Am.Chem.Soc., 132, 2010
2RER
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BU of 2rer by Molmil
Crystal structure of the aromatase/cyclase domain of TcmN from Streptomyces glaucescens
分子名称: Multifunctional cyclase-dehydratase-3-O-methyl transferase tcmN
著者Ames, B.D, Korman, T.P, Vu, T.N, Tsai, S.C.
登録日2007-09-26
公開日2008-04-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure and functional analysis of tetracenomycin ARO/CYC: implications for cyclization specificity of aromatic polyketides.
Proc.Natl.Acad.Sci.Usa, 105, 2008

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