3QRW
Actinorhodin Polyketide Ketoreductase Mutant P94L bound to NADPH
Summary for 3QRW
| Entry DOI | 10.2210/pdb3qrw/pdb |
| Descriptor | ketoacyl reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, FORMIC ACID, ... (4 entities in total) |
| Functional Keywords | actinorhodin, polyketide, ketoreductase, short-chain dehydrogenase/reductase, oxidoreductase, type ii polyketide ketoreductase, rossmann fold |
| Biological source | Streptomyces coelicolor |
| Total number of polymer chains | 2 |
| Total formula weight | 60497.67 |
| Authors | Korman, T.P.,Javidpour, P.,Tsai, S.-C. (deposition date: 2011-02-18, release date: 2011-05-25, Last modification date: 2024-02-21) |
| Primary citation | Javidpour, P.,Korman, T.P.,Shakya, G.,Tsai, S.C. Structural and Biochemical Analyses of Regio- and Stereospecificities Observed in a Type II Polyketide Ketoreductase. Biochemistry, 50:4638-4649, 2011 Cited by PubMed: 21506596DOI: 10.1021/bi200335f PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.792 Å) |
Structure validation
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