3HRR

The Product Template Domain from PksA with Harris Compound Bound

Summary for 3HRR

Entry DOI	10.2210/pdb3hrr/pdb
Related	3HRQ
Descriptor	Aflatoxin biosynthesis polyketide synthase, 1-(3-acetyl-4,5-dihydroxy-7-methoxynaphthalen-2-yl)propan-2-one (3 entities in total)
Functional Keywords	pksa, aflatoxin, norsolorinic acid, polyketide, polyketide synthase, pks, iterative type i pks, harris compound, hot-dog fold, acyltransferase, multifunctional enzyme, phosphopantetheine, transferase, transcription
Biological source	Aspergillus parasiticus
Total number of polymer chains	2
Total formula weight	79063.68
Authors	Korman, T.P.,Tsai, S.C. (deposition date: 2009-06-09, release date: 2009-10-20, Last modification date: 2023-09-06)
Primary citation	Crawford, J.M.,Korman, T.P.,Labonte, J.W.,Vagstad, A.L.,Hill, E.A.,Kamari-Bidkorpeh, O.,Tsai, S.C.,Townsend, C.A. Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization. Nature, 461:1139-1143, 2009 Cited by PubMed: 19847268 DOI: 10.1038/nature08475 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation