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PDB: 103 件
6D0N
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BU of 6d0n by Molmil
Crystal structure of a CLC-type fluoride/proton antiporter, V319G mutant
分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, CLC-type fluoride/proton antiporter, DECYL-BETA-D-MALTOPYRANOSIDE, ...
著者Last, N.B, Stockbridge, R.B, Wilson, A.E, Shane, T, Kolmakova-Partensky, L, Koide, A, Koide, S, Miller, C.
登録日2018-04-10
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献A CLC-type F-/H+antiporter in ion-swapped conformations.
Nat. Struct. Mol. Biol., 25, 2018
6D0K
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BU of 6d0k by Molmil
Crystal structure of a CLC-type fluoride/proton antiporter, E118Q mutant
分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, CLC-type fluoride/proton antiporter, DECYL-BETA-D-MALTOPYRANOSIDE, ...
著者Last, N.B, Stockbridge, R.B, Wilson, A.E, Shane, T, Kolmakova-Partensky, L, Koide, A, Koide, S, Miller, C.
登録日2018-04-10
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献A CLC-type F-/H+antiporter in ion-swapped conformations.
Nat. Struct. Mol. Biol., 25, 2018
6D0J
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BU of 6d0j by Molmil
Crystal structure of a CLC-type fluoride/proton antiporter
分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, CLC-type fluoride/proton antiporter, DECYL-BETA-D-MALTOPYRANOSIDE, ...
著者Last, N.B, Stockbridge, R.B, Wilson, A.E, Shane, T, Kolmakova-Partensky, L, Koide, A, Koide, S, Miller, C.
登録日2018-04-10
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A CLC-type F-/H+antiporter in ion-swapped conformations.
Nat. Struct. Mol. Biol., 25, 2018
3CH8
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BU of 3ch8 by Molmil
The crystal structure of PDZ-Fibronectin fusion protein
分子名称: C-terminal octapeptide from protein ARVCF, MAGNESIUM ION, fusion protein PDZ-Fibronectin,Fibronectin
著者Makabe, K, Huang, J, Koide, A, Koide, S.
登録日2008-03-08
公開日2009-03-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for exquisite specificity of affinity clamps, synthetic binding proteins generated through directed domain-interface evolution.
J.Mol.Biol., 392, 2009
3EC5
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BU of 3ec5 by Molmil
The crystal structure of Thioflavin-T (ThT) binding OspA mutant
分子名称: Outer Surface Protein A, TETRAETHYLENE GLYCOL
著者Biancalana, M, Makabe, K, Koide, A, Koide, S.
登録日2008-08-28
公開日2009-02-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Molecular mechanism of thioflavin-T binding to the surface of beta-rich peptide self-assemblies
J.Mol.Biol., 385, 2009
4IOF
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BU of 4iof by Molmil
Crystal structure analysis of Fab-bound human Insulin Degrading Enzyme (IDE)
分子名称: Fab-bound IDE, heavy chain, light chain, ...
著者McCord, L.A, Liang, W.G, Hoey, R, Dowdell, E, Koide, A, Koide, S, Tang, W.J.
登録日2013-01-07
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.353 Å)
主引用文献Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme.
Proc.Natl.Acad.Sci.USA, 110, 2013
5E95
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BU of 5e95 by Molmil
Crystal Structure of Mb(NS1)/H-Ras Complex
分子名称: GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Eguchi, R.R, Sha, F, Gupta, A, Koide, A, Koide, S.
登録日2015-10-14
公開日2016-11-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.402 Å)
主引用文献Inhibition of RAS function through targeting an allosteric regulatory site.
Nat. Chem. Biol., 13, 2017
5DC9
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BU of 5dc9 by Molmil
CRYSTAL STRUCTURE OF MONOBODY AS25/ABL1 SH2 DOMAIN COMPLEX, CRYSTAL B
分子名称: AS25 monobody, GLYCEROL, IMIDAZOLE, ...
著者Wojcik, J.B, Koide, A, Koide, S.
登録日2015-08-23
公開日2016-03-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase Interface.
J.Biol.Chem., 291, 2016
5DC4
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BU of 5dc4 by Molmil
CRYSTAL STRUCTURE OF MONOBODY AS25/ABL1 SH2 DOMAIN COMPLEX, CRYSTAL A
分子名称: AS25 monobody, GLYCEROL, Tyrosine-protein kinase ABL1
著者Wojcik, J.B, Koide, A, Koide, S.
登録日2015-08-23
公開日2016-03-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase Interface.
J.Biol.Chem., 291, 2016
4M1C
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BU of 4m1c by Molmil
Crystal Structure Analysis of Fab-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Amyloid-Beta (1-40)
分子名称: Amyloid beta A4 protein, Fab-bound IDE, heavy chain, ...
著者McCord, L.M, Liang, W, Farcasanu, M, Scherpelz, K, Meredith, S.C, Koide, S, Tang, W.J.
登録日2013-08-02
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5007 Å)
主引用文献Crystal Structure Analysis of Fab-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Amyloid-Beta (1-40)
To be Published
4YHP
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BU of 4yhp by Molmil
Crystal structure of 309M3-B Fab in complex with H3K9me3 peptide
分子名称: Fab Heavy Chain, Fab Light Chain, H3K9me3 peptide
著者Hattori, T, Dementieva, I.S, Montano, S.P, Koide, S.
登録日2015-02-27
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation.
Proc.Natl.Acad.Sci.USA, 113, 2016
4YHZ
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BU of 4yhz by Molmil
Crystal structure of 304M3-B Fab in complex with H3K4me3 peptide
分子名称: Fab Heavy Chain, Fab Light Chain, GLYCEROL, ...
著者Hattori, T, Dementieva, I.S, Montano, S.P, Koide, S.
登録日2015-02-27
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation.
Proc.Natl.Acad.Sci.USA, 113, 2016
4YHY
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BU of 4yhy by Molmil
Crystal structure of 309M3-B in complex with trimethylated Lys
分子名称: Fab Heavy Chain, Fab Light Chain, N-TRIMETHYLLYSINE
著者Hattori, T, Dementieva, I.S, Montano, S.P, Koide, S.
登録日2015-02-27
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation.
Proc.Natl.Acad.Sci.USA, 113, 2016
2OYB
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BU of 2oyb by Molmil
The crystal structure of OspA mutant
分子名称: Outer surface protein A
著者Makabe, K, Biancalana, M, Terechko, V, Koide, S.
登録日2007-02-21
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Aromatic cross-strand ladders control the structure and stability of beta-rich peptide self-assembly mimics
J.Mol.Biol., 383, 2008
2OBG
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BU of 2obg by Molmil
Crystal Structure of Monobody MBP-74/Maltose Binding Protein Fusion Complex
分子名称: Maltose Binding periplasmic Protein and Monobody MBP-74 Fusion protein
著者Gilbreth, R.N, Tereshko, V, Koide, S.
登録日2006-12-19
公開日2007-03-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献High-affinity single-domain binding proteins with a binary-code interface.
Proc.Natl.Acad.Sci.Usa, 104, 2007
5MTJ
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BU of 5mtj by Molmil
Yes1-SH2 in complex with monobody Mb(Yes_1)
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Monobody Mb(Yes_1), SULFATE ION, ...
著者Sha, F, Kukenshoner, T, Koide, S, Hantschel, O.
登録日2017-01-09
公開日2017-04-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies.
J. Mol. Biol., 429, 2017
5MTM
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BU of 5mtm by Molmil
Monobody Mb(Lck_3) bound to Lck-SH2 domain
分子名称: Monobody Mb(Lck_3), Tyrosine-protein kinase Lck, ZINC ION
著者Pojer, F, Kukenshoner, T, Koide, S, Hantschel, O.
登録日2017-01-10
公開日2017-04-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.405 Å)
主引用文献Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies.
J. Mol. Biol., 429, 2017
5MTN
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BU of 5mtn by Molmil
Monobody Mb(Lck_1) bound to Lck-Sh2
分子名称: Monobody Mb(Lck_1), SULFATE ION, Tyrosine-protein kinase Lck
著者Pojer, F, Kukenshoner, T, Koide, S, Hantschel, O.
登録日2017-01-10
公開日2017-04-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies.
J. Mol. Biol., 429, 2017
3IVK
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BU of 3ivk by Molmil
Crystal Structure of the Catalytic Core of an RNA Polymerase Ribozyme Complexed with an Antigen Binding Antibody Fragment
分子名称: CADMIUM ION, CHLORIDE ION, Fab heavy chain, ...
著者Koldobskaya, Y, Duguid, E.M, Shechner, D.M, Koide, S, Kossiakoff, A.A, Bartel, D.P, Piccirilli, J.A.
登録日2009-09-01
公開日2010-03-02
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of the catalytic core of an RNA-polymerase ribozyme.
Science, 326, 2009
7L0F
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BU of 7l0f by Molmil
Monobody 12VC3 Bound to HRAS(WT)
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase HRas, MAGNESIUM ION, ...
著者Teng, K.W, Hattori, T, Tsai, S, Koide, S.
登録日2020-12-11
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Selective and noncovalent targeting of RAS mutants for inhibition and degradation.
Nat Commun, 12, 2021
7L0G
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BU of 7l0g by Molmil
Monobody 12VC1 Bound to HRAS(G12C)
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase HRas, MAGNESIUM ION, ...
著者Teng, K.W, Hattori, T, Tsai, S, Koide, S.
登録日2020-12-11
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Selective and noncovalent targeting of RAS mutants for inhibition and degradation.
Nat Commun, 12, 2021
2FKG
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BU of 2fkg by Molmil
The Crystal Structure of Engineered OspA
分子名称: Outer Surface Protein A
著者Makabe, K, Terechko, V, Gawlak, G, Yan, S, Koide, S.
登録日2006-01-04
公開日2006-11-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Atomic structures of peptide self-assembly mimics.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3CSB
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BU of 3csb by Molmil
Crystal Structure of Monobody YSX1/Maltose Binding Protein Fusion Complex
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ...
著者Gilbreth, R.N, Koide, S.
登録日2008-04-09
公開日2008-07-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein-Protein Interfaces
J.Mol.Biol., 381, 2008
2HKD
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BU of 2hkd by Molmil
The crystal structure of engineered OSPA
分子名称: Outer Surface Protein A, TETRAETHYLENE GLYCOL
著者Makabe, K, Terechko, V, Koide, S.
登録日2006-07-03
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Atomic structures of peptide self-assembly mimics.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2FKJ
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BU of 2fkj by Molmil
The crystal structure of engineered OspA
分子名称: Outer Surface Protein A
著者Makabe, K, Terechko, V, Gawlak, G, Yan, S, Koide, S.
登録日2006-01-04
公開日2006-11-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Atomic structures of peptide self-assembly mimics.
Proc.Natl.Acad.Sci.Usa, 103, 2006

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