8FYM
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![BU of 8fym by Molmil](/molmil-images/mine/8fym) | Crystal structure of Fab235 in complex with MPER peptide | Descriptor: | ALA-SER-LEU-TRP-ASN-TRP-PHE-ASN-ILE-THR-ASN-TRP-LEU-TRP-TYR-ILE-LYS-LYS-LYS, CHLORIDE ION, Fab235, ... | Authors: | Tan, K, Kim, M, Reinherz, E.L. | Deposit date: | 2023-01-26 | Release date: | 2023-10-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility. Nat Commun, 14, 2023
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8FWF
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![BU of 8fwf by Molmil](/molmil-images/mine/8fwf) | Crystal structure of Apo form Fab235 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Tan, K, Kim, M, Reinherz, E.L. | Deposit date: | 2023-01-21 | Release date: | 2023-10-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility. Nat Commun, 14, 2023
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8FXJ
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![BU of 8fxj by Molmil](/molmil-images/mine/8fxj) | Crystal structure of Fab460 | Descriptor: | ACETATE ION, CHLORIDE ION, Fab460, ... | Authors: | Tan, K, Kim, M, Reinherz, E.L. | Deposit date: | 2023-01-24 | Release date: | 2023-10-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility. Nat Commun, 14, 2023
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8FZ2
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![BU of 8fz2 by Molmil](/molmil-images/mine/8fz2) | Crystal structure of Fab460 in complex with MPER peptide | Descriptor: | Fab460, H chain, L chain, ... | Authors: | Tan, K, Kim, M, Reinherz, E.L. | Deposit date: | 2023-01-27 | Release date: | 2023-10-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility. Nat Commun, 14, 2023
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8HHD
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![BU of 8hhd by Molmil](/molmil-images/mine/8hhd) | Crystal structure of PaMurU | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Nucleotidyl transferase, SULFATE ION | Authors: | Shin, D.H, Jo, S.R, Kim, M.S. | Deposit date: | 2022-11-16 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Crystal structure of PAMurU To Be Published
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3B21
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![BU of 3b21 by Molmil](/molmil-images/mine/3b21) | |
6JQ8
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![BU of 6jq8 by Molmil](/molmil-images/mine/6jq8) | |
6SDF
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![BU of 6sdf by Molmil](/molmil-images/mine/6sdf) | N-terminal SH3 domain of Grb2 protein | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Growth factor receptor-bound protein 2 | Authors: | Bolgov, A.A, Korban, S.A, Luzik, D.A, Rogacheva, O.N, Zhemkov, V.A, Kim, M, Skrynnikov, N.R, Bezprozvanny, I.B. | Deposit date: | 2019-07-26 | Release date: | 2020-01-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the SH3 domain of growth factor receptor-bound protein 2. Acta Crystallogr.,Sect.F, 76, 2020
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3CLJ
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![BU of 3clj by Molmil](/molmil-images/mine/3clj) | Structure of the RNA polymerase II CTD-interacting domain of Nrd1 | Descriptor: | GLYCEROL, Protein NRD1, SULFATE ION | Authors: | Vasiljeva, L, Kim, M, Mutschler, H, Buratowski, S, Meinhart, A. | Deposit date: | 2008-03-19 | Release date: | 2008-07-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Nrd1-Nab3-Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain. Nat.Struct.Mol.Biol., 15, 2008
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7VYT
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![BU of 7vyt by Molmil](/molmil-images/mine/7vyt) | Crystal structure of human TIGIT(23-129) in complex with the scFv fragment of anti-TIGIT antibody MG1131 | Descriptor: | CITRATE ANION, MG1131 heavy chain variable region, MG1131 light chain variable region, ... | Authors: | Jeong, B.-S, Nam, H, Kim, M, Oh, B.-H. | Deposit date: | 2021-11-15 | Release date: | 2022-03-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Structural and functional characterization of a monoclonal antibody blocking TIGIT. Mabs, 14, 2022
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7ER9
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![BU of 7er9 by Molmil](/molmil-images/mine/7er9) | Crystal structure of human Biliverdin IX-beta reductase B with Febuxostat (TEI) | Descriptor: | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE-CARBOXYLIC ACID, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H. | Deposit date: | 2021-05-06 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target. J.Med.Chem., 65, 2022
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7ERE
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![BU of 7ere by Molmil](/molmil-images/mine/7ere) | Crystal structure of human Biliverdin IX-beta reductase B with Pyrantel Pamoate (PPA) | Descriptor: | 4-[(3-carboxy-2-oxidanyl-naphthalen-1-yl)methyl]-3-oxidanyl-naphthalene-2-carboxylic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H. | Deposit date: | 2021-05-06 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target. J.Med.Chem., 65, 2022
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7ER6
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![BU of 7er6 by Molmil](/molmil-images/mine/7er6) | Crystal structure of human Biliverdin IX-beta reductase B | Descriptor: | Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION | Authors: | Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H. | Deposit date: | 2021-05-06 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target. J.Med.Chem., 65, 2022
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7ER7
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![BU of 7er7 by Molmil](/molmil-images/mine/7er7) | Crystal structure of hyman Biliverdin IX-beta reductase B with Tamibarotene (A80) | Descriptor: | 4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H. | Deposit date: | 2021-05-06 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target. J.Med.Chem., 65, 2022
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7ERC
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![BU of 7erc by Molmil](/molmil-images/mine/7erc) | Crystal structure of human Biliverdin IX-beta reductase B with Deferasirox (ICL) | Descriptor: | 4-[3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H. | Deposit date: | 2021-05-06 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target. J.Med.Chem., 65, 2022
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7ERD
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![BU of 7erd by Molmil](/molmil-images/mine/7erd) | Crystal structure of human Biliverdin IX-beta reductase B with Flunixin Meglumin (FMG) | Descriptor: | 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]pyridine-3-carboxylic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H. | Deposit date: | 2021-05-06 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target. J.Med.Chem., 65, 2022
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7ER8
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![BU of 7er8 by Molmil](/molmil-images/mine/7er8) | Crystal structure of human Biliverdin IX-beta reductase B with Sulfasalazine (SAS) | Descriptor: | 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H. | Deposit date: | 2021-05-06 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target. J.Med.Chem., 65, 2022
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7ERB
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![BU of 7erb by Molmil](/molmil-images/mine/7erb) | Crystal structure of human Biliverdin IX-beta reductase B with Ataluren (PTC) | Descriptor: | 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H. | Deposit date: | 2021-05-06 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target. J.Med.Chem., 65, 2022
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7ERA
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![BU of 7era by Molmil](/molmil-images/mine/7era) | Crystal structure of human Biliverdin IX-beta reductase B with Olsalazine Sodium (OSS) | Descriptor: | 5-[(E)-(3-carboxy-4-oxidanyl-phenyl)diazenyl]-2-oxidanyl-benzoic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H. | Deposit date: | 2021-05-06 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target. J.Med.Chem., 65, 2022
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7YA8
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![BU of 7ya8 by Molmil](/molmil-images/mine/7ya8) | The crystal structure of IpaH2.5 LRR domain | Descriptor: | RING-type E3 ubiquitin transferase | Authors: | Hiragi, K, Nishide, A, Takagi, K, Iwai, K, Kim, M, Mizushima, T. | Deposit date: | 2022-06-27 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural insight into the recognition of the linear ubiquitin assembly complex by Shigella E3 ligase IpaH1.4/2.5. J.Biochem., 173, 2023
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7YA7
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![BU of 7ya7 by Molmil](/molmil-images/mine/7ya7) | The crystal structure of IpaH1.4 LRR domain | Descriptor: | RING-type E3 ubiquitin transferase | Authors: | Hiragi, K, Nishide, A, Takagi, K, Iwai, K, Kim, M, Mizushima, T. | Deposit date: | 2022-06-27 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural insight into the recognition of the linear ubiquitin assembly complex by Shigella E3 ligase IpaH1.4/2.5. J.Biochem., 173, 2023
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6CIJ
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![BU of 6cij by Molmil](/molmil-images/mine/6cij) | Cryo-EM structure of mouse RAG1/2 HFC complex containing partial HMGB1 linker(3.9 A) | Descriptor: | CALCIUM ION, DNA (30-MER), DNA (41-MER), ... | Authors: | Chen, X, Kim, M, Chuenchor, W, Cui, Y, Zhang, X, Zhou, Z.H, Gellert, M, Yang, W. | Deposit date: | 2018-02-24 | Release date: | 2018-04-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cracking the DNA Code for V(D)J Recombination. Mol. Cell, 70, 2018
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6CG0
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![BU of 6cg0 by Molmil](/molmil-images/mine/6cg0) | Cryo-EM structure of mouse RAG1/2 HFC complex (3.17 A) | Descriptor: | CALCIUM ION, DNA (30-MER), DNA (41-MER), ... | Authors: | Chen, X, Kim, M, Chuenchor, W, Cui, Y, Zhang, X, Zhou, Z.H, Gellert, M, Yang, W. | Deposit date: | 2018-02-19 | Release date: | 2018-04-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Cracking the DNA Code for V(D)J Recombination. Mol. Cell, 70, 2018
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6KYV
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![BU of 6kyv by Molmil](/molmil-images/mine/6kyv) | Crystal Structure of RIG-I and hairpin RNA with G-U wobble base pairs | Descriptor: | Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*UP*UP*GP*CP*C)-3'), ZINC ION | Authors: | Kim, K.-H, Hwang, J, Kim, J.H, Son, K.-P, Jang, Y, Kim, M, Kang, S.-J, Lee, J.-O, Choi, B.-S. | Deposit date: | 2019-09-20 | Release date: | 2020-09-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural and biophysical properties of RIG-I bound to dsRNA with G-U wobble base pairs. Rna Biol., 17, 2020
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6L0Y
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![BU of 6l0y by Molmil](/molmil-images/mine/6l0y) | Structure of dsRNA with G-U wobble base pairs | Descriptor: | RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*UP*UP*GP*CP*C)-3') | Authors: | Kim, K.-H, Hwang, J, Kim, J.H, Son, K.-P, Jang, Y, Kim, M, Kang, S.-J, Lee, J.-O, Choi, B.-S. | Deposit date: | 2019-09-27 | Release date: | 2020-09-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of dsRNA with G-U wobble base pairs To Be Published
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