5D92
 
 | | Structure of a phosphatidylinositolphosphate (PIP) synthase from Renibacterium Salmoninarum | | 分子名称: | 5'-O-[(R)-{[(S)-{(2R)-2,3-bis[(9E)-octadec-9-enoyloxy]propoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine, AF2299 protein,Phosphatidylinositol synthase, MAGNESIUM ION, ... | | 著者 | Clarke, O.B, Tomasek, D.T, Jorge, C.D, Belcher Dufrisne, M, Kim, M, Banerjee, S, Rajashankar, K.R, Hendrickson, W.A, Santos, H, Mancia, F. | | 登録日 | 2015-08-18 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.62 Å) | | 主引用文献 | Structural basis for phosphatidylinositol-phosphate biosynthesis.
Nat Commun, 6, 2015
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6SDF
 | | N-terminal SH3 domain of Grb2 protein | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Growth factor receptor-bound protein 2 | | 著者 | Bolgov, A.A, Korban, S.A, Luzik, D.A, Rogacheva, O.N, Zhemkov, V.A, Kim, M, Skrynnikov, N.R, Bezprozvanny, I.B. | | 登録日 | 2019-07-26 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of the SH3 domain of growth factor receptor-bound protein 2.
Acta Crystallogr.,Sect.F, 76, 2020
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6CG0
 | | Cryo-EM structure of mouse RAG1/2 HFC complex (3.17 A) | | 分子名称: | CALCIUM ION, DNA (30-MER), DNA (41-MER), ... | | 著者 | Chen, X, Kim, M, Chuenchor, W, Cui, Y, Zhang, X, Zhou, Z.H, Gellert, M, Yang, W. | | 登録日 | 2018-02-19 | | 公開日 | 2018-04-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
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8SLU
 | | Crystal structure of human STEP (PTPN5) at cryogenic temperature (100 K) and high pressure (205 MPa) | | 分子名称: | GLYCEROL, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 5 | | 著者 | Ebrahim, A, Guerrero, L, Riley, B.T, Kim, M, Huang, Q, Finke, A.D, Keedy, D.A. | | 登録日 | 2023-04-24 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Pushed to extremes: distinct effects of high temperature vs. pressure on the structure of an atypical phosphatase.
Biorxiv, 2023
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8SLT
 | | Crystal structure of human STEP (PTPN5) at physiological temperature (310 K) and ambient pressure (0.1 MPa) | | 分子名称: | SULFATE ION, Tyrosine-protein phosphatase non-receptor type 5 | | 著者 | Ebrahim, A, Guerrero, L, Riley, B.T, Kim, M, Huang, Q, Finke, A.D, Keedy, D.A. | | 登録日 | 2023-04-24 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Pushed to extremes: distinct effects of high temperature vs. pressure on the structure of an atypical phosphatase.
Biorxiv, 2023
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8SLS
 | | Crystal structure of human STEP (PTPN5) at cryogenic temperature (100 K) and ambient pressure (0.1 MPa) | | 分子名称: | GLYCEROL, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 5 | | 著者 | Ebrahim, A, Guerrero, L, Riley, B.T, Kim, M, Huang, Q, Finke, A.D, Keedy, D.A. | | 登録日 | 2023-04-24 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Pushed to extremes: distinct effects of high temperature vs. pressure on the structure of an atypical phosphatase.
Biorxiv, 2023
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6E2B
 | | Ubiquitin in complex with Pt(2-phenilpyridine)(PPh3) | | 分子名称: | GLYCEROL, SULFATE ION, Ubiquitin, ... | | 著者 | Zhemkov, V.A, Kim, M. | | 登録日 | 2018-07-11 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Reactions of Cyclometalated Platinum(II) [Pt(N∧C)(PR3)Cl] Complexes with Imidazole and Imidazole-Containing Biomolecules: Fine-Tuning of Reactivity and Photophysical Properties via Ligand Design.
Inorg Chem, 58, 2019
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2QOJ
 | | Coevolution of a homing endonuclease and its host target sequence | | 分子名称: | I-AniI DNA target seq1, I-AniI DNA target seq2, LAGLIDADG endonuclease, ... | | 著者 | Scalley-Kim, M, McConnell Smith, A, Stoddard, B.L. | | 登録日 | 2007-07-20 | | 公開日 | 2008-11-11 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Coevolution of a homing endonuclease and its host target sequence.
J.Mol.Biol., 372, 2007
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5Y16
 | | Crystal structure of human DUSP28(Y102H) | | 分子名称: | CHLORIDE ION, Dual specificity phosphatase 28, PHOSPHATE ION | | 著者 | Ku, B, Kim, M, Kim, S.J, Ryu, S.E. | | 登録日 | 2017-07-19 | | 公開日 | 2017-11-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.399 Å) | | 主引用文献 | Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28
PLoS ONE, 12, 2017
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6KYV
 | | Crystal Structure of RIG-I and hairpin RNA with G-U wobble base pairs | | 分子名称: | Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*UP*UP*GP*CP*C)-3'), ZINC ION | | 著者 | Kim, K.-H, Hwang, J, Kim, J.H, Son, K.-P, Jang, Y, Kim, M, Kang, S.-J, Lee, J.-O, Choi, B.-S. | | 登録日 | 2019-09-20 | | 公開日 | 2020-09-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural and biophysical properties of RIG-I bound to dsRNA with G-U wobble base pairs.
Rna Biol., 17, 2020
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6L0Y
 | | Structure of dsRNA with G-U wobble base pairs | | 分子名称: | RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*UP*UP*GP*CP*C)-3') | | 著者 | Kim, K.-H, Hwang, J, Kim, J.H, Son, K.-P, Jang, Y, Kim, M, Kang, S.-J, Lee, J.-O, Choi, B.-S. | | 登録日 | 2019-09-27 | | 公開日 | 2020-09-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of dsRNA with G-U wobble base pairs
To Be Published
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1SIX
 | | Mycobacterium tuberculosis dUTPase complexed with magnesium and alpha,beta-imido-dUTP | | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | | 著者 | Sawaya, M.R, Chan, S, Segelke, B, Lekin, T, Krupka, H, Cho, U.-S, Kim, M, So, M, Kim, C.-Y, Naranjo, C.M, Rogers, Y.C, Park, M.S, Waldo, G.S, Pashkov, I, Cascio, D, Yeates, T.O, Perry, J.L, Terwilliger, T.C, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2004-03-01 | | 公開日 | 2004-03-09 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
J.Mol.Biol., 341, 2004
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4WTH
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4YS9
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7RZY
 | | CryoEM structure of Vibrio cholerae transposon Tn6677 AAA+ ATPase TnsC | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Tn6677 Vibrio cholerae transposon TnsC (VchTnsC) | | 著者 | Hoffmann, F.T, Kim, M, Beh, L.Y, Wang, J, Vo, P.L.H, Gelsinger, D.R, Acree, C, Mohabir, J.T, Fernandez, I.S, Sternberg, S.H. | | 登録日 | 2021-08-28 | | 公開日 | 2022-06-08 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Selective TnsC recruitment enhances the fidelity of RNA-guided transposition.
Nature, 609, 2022
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1WMN
 | | Crystal structure of topaquinone-containing amine oxidase activated by cobalt ion | | 分子名称: | COBALT (II) ION, Phenylethylamine oxidase | | 著者 | Okajima, T, Kishishita, S, Chiu, Y.C, Murakawa, T, Kim, M, Yamaguchi, H, Hirota, S, Kuroda, S, Tanizawa, K. | | 登録日 | 2004-07-13 | | 公開日 | 2005-08-02 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Reinvestigation of metal ion specificity for quinone cofactor biogenesis in bacterial copper amine oxidase
Biochemistry, 44, 2005
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1WMO
 | | Crystal structure of topaquinone-containing amine oxidase activated by nickel ion | | 分子名称: | NICKEL (II) ION, Phenylethylamine oxidase | | 著者 | Okajima, T, Kishishita, S, Chiu, Y.C, Murakawa, T, Kim, M, Yamaguchi, H, Hirota, S, Kuroda, S, Tanizawa, K. | | 登録日 | 2004-07-13 | | 公開日 | 2005-08-02 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Reinvestigation of metal ion specificity for quinone cofactor biogenesis in bacterial copper amine oxidase
Biochemistry, 44, 2005
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1WMP
 | | Crystal structure of amine oxidase complexed with cobalt ion | | 分子名称: | COBALT (II) ION, Phenylethylamine oxidase | | 著者 | Okajima, T, Kishishita, S, Chiu, Y.C, Murakawa, T, Kim, M, Yamaguchi, H, Hirota, S, Kuroda, S, Tanizawa, K. | | 登録日 | 2004-07-13 | | 公開日 | 2005-08-02 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Reinvestigation of metal ion specificity for quinone cofactor biogenesis in bacterial copper amine oxidase
Biochemistry, 44, 2005
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8FYM
 | | Crystal structure of Fab235 in complex with MPER peptide | | 分子名称: | ALA-SER-LEU-TRP-ASN-TRP-PHE-ASN-ILE-THR-ASN-TRP-LEU-TRP-TYR-ILE-LYS-LYS-LYS, CHLORIDE ION, Fab235, ... | | 著者 | Tan, K, Kim, M, Reinherz, E.L. | | 登録日 | 2023-01-26 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.
Nat Commun, 14, 2023
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8FWF
 | | Crystal structure of Apo form Fab235 | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Tan, K, Kim, M, Reinherz, E.L. | | 登録日 | 2023-01-21 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.
Nat Commun, 14, 2023
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8FXJ
 | | Crystal structure of Fab460 | | 分子名称: | ACETATE ION, CHLORIDE ION, Fab460, ... | | 著者 | Tan, K, Kim, M, Reinherz, E.L. | | 登録日 | 2023-01-24 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.
Nat Commun, 14, 2023
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8FZ2
 | | Crystal structure of Fab460 in complex with MPER peptide | | 分子名称: | Fab460, H chain, L chain, ... | | 著者 | Tan, K, Kim, M, Reinherz, E.L. | | 登録日 | 2023-01-27 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.
Nat Commun, 14, 2023
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7VYT
 | | Crystal structure of human TIGIT(23-129) in complex with the scFv fragment of anti-TIGIT antibody MG1131 | | 分子名称: | CITRATE ANION, MG1131 heavy chain variable region, MG1131 light chain variable region, ... | | 著者 | Jeong, B.-S, Nam, H, Kim, M, Oh, B.-H. | | 登録日 | 2021-11-15 | | 公開日 | 2022-03-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Structural and functional characterization of a monoclonal antibody blocking TIGIT.
Mabs, 14, 2022
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3B21
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7ER9
 | | Crystal structure of human Biliverdin IX-beta reductase B with Febuxostat (TEI) | | 分子名称: | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE-CARBOXYLIC ACID, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H. | | 登録日 | 2021-05-06 | | 公開日 | 2022-01-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
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