Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 297 results

6C0U
DownloadVisualize
BU of 6c0u by Molmil
Crystal structure of cAMP-dependent protein kinase Calpha subunit bound with N46
Descriptor: DIMETHYL SULFOXIDE, N-[(3R,4R)-4-{[4-(2-fluoro-3-methoxy-6-propoxybenzene-1-carbonyl)benzene-1-carbonyl]amino}pyrrolidin-3-yl]-1H-indazole-5-carboxamide, PHOSPHATE ION, ...
Authors:Qin, L, Sankaran, B, Kim, C.
Deposit date:2018-01-02
Release date:2018-05-30
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis for selective inhibition of human PKG I alpha by the balanol-like compound N46.
J. Biol. Chem., 293, 2018
7L9A
DownloadVisualize
BU of 7l9a by Molmil
Crystal structure of BRDT bromodomain 2 in complex with CDD-1102
Descriptor: BETA-MERCAPTOETHANOL, Bromodomain testis-specific protein, N~1~-(5-{[3-(4-amino-2-methylphenyl)-1-methyl-1H-indazole-5-carbonyl]amino}-2-methylphenyl)-N~4~-methylbenzene-1,4-dicarboxamide
Authors:Sharma, R, Kaur, G, Yu, Z, Ku, A.F, Anglin, J.L, Ucisik, M.N, Faver, J.C, Sankaran, B, Kim, C, Matzuk, M.M.
Deposit date:2021-01-03
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Discovery and characterization of bromodomain 2-specific inhibitors of BRDT.
Proc.Natl.Acad.Sci.USA, 118, 2021
5J48
DownloadVisualize
BU of 5j48 by Molmil
PKG I's Carboyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-pCPT-cGMP
Descriptor: 1,2-ETHANEDIOL, 2-amino-8-[(4-chlorophenyl)sulfanyl]-9-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-3,9-dihydro-6H-purin-6-one, CALCIUM ION, ...
Authors:Campbell, J.C, Sankaran, B, Kim, C.W.
Deposit date:2016-03-31
Release date:2017-04-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Structural Basis of Analog Specificity in PKG I and II.
ACS Chem. Biol., 12, 2017
5JD7
DownloadVisualize
BU of 5jd7 by Molmil
PKG I's Carboxyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with PET-cGMP
Descriptor: 3-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-6-phenyl-3,4-dihydro-9H-imidazo[1,2-a]purin-9-one, cGMP-dependent protein kinase 1
Authors:Campbell, J.C, Sankaran, B, Kim, C.W.
Deposit date:2016-04-15
Release date:2017-08-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:Structural Basis of Analog Specificity in PKG I and II.
ACS Chem. Biol., 12, 2017
3B4W
DownloadVisualize
BU of 3b4w by Molmil
Crystal structure of Mycobacterium tuberculosis aldehyde dehydrogenase complexed with NAD+
Descriptor: Aldehyde dehydrogenase, ETHANOL, GLYCEROL, ...
Authors:Moon, J.H, Lyon, A.E, Yu, M, Hung, L.-W, Terwilliger, T, Kim, C.-Y, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC)
Deposit date:2007-10-24
Release date:2007-11-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structure of aldehyde dehydrogenase from Mycobacterium tuberculosis complexed with NAD+.
To Be Published
1IF8
DownloadVisualize
BU of 1if8 by Molmil
Carbonic Anhydrase II Complexed With (S)-N-(3-Indol-1-yl-2-methyl-propyl)-4-sulfamoyl-benzamide
Descriptor: (S)-N-(3-INDOL-1-YL-2-METHYL-PROPYL)-4-SULFAMOYL-BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ...
Authors:Grzybowski, B.A, Ishchenko, A.V, Kim, C.-Y, Topalov, G, Chapman, R, Christianson, D.W, Whitesides, G.M, Shakhnovich, E.I.
Deposit date:2001-04-12
Release date:2001-05-02
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Combinatorial computational method gives new picomolar ligands for a known enzyme.
Proc.Natl.Acad.Sci.USA, 99, 2002
6NAZ
DownloadVisualize
BU of 6naz by Molmil
Crystal structure of DIRAS 2/3 chimera in complex with GDP
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, GTP-binding protein Di-Ras2,GTP-binding protein Di-Ras3,GTP-binding protein Di-Ras2, ...
Authors:Gilbert, Y.H, Reger, A, Sharma, R, Bast, J, Kim, C.
Deposit date:2018-12-06
Release date:2019-12-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.081 Å)
Cite:Crystal structure of DIRAS 2/3 chimera in complex with GDP
To Be Published
1IF9
DownloadVisualize
BU of 1if9 by Molmil
Carbonic Anhydrase II Complexed With N-[2-(1H-Indol-5-yl)-butyl]-4-sulfamoyl-benzamide
Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, N-[2-(1H-INDOL-5-YL)-BUTYL]-4-SULFAMOYL-BENZAMIDE, ...
Authors:Grzybowski, B.A, Ishchenko, A.V, Kim, C.-Y, Topalov, G, Chapman, R, Christianson, D.W, Whitesides, G.M, Shakhnovich, E.I.
Deposit date:2001-04-12
Release date:2001-05-02
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Combinatorial computational method gives new picomolar ligands for a known enzyme.
Proc.Natl.Acad.Sci.USA, 99, 2002
1IF7
DownloadVisualize
BU of 1if7 by Molmil
Carbonic Anhydrase II Complexed With (R)-N-(3-Indol-1-yl-2-methyl-propyl)-4-sulfamoyl-benzamide
Descriptor: (R)-N-(3-INDOL-1-YL-2-METHYL-PROPYL)-4-SULFAMOYL-BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ...
Authors:Grzybowski, B.A, Ishchenko, A.V, Kim, C.-Y, Topalov, G, Chapman, R, Christianson, D.W, Whitesides, G.M, Shakhnovich, E.I.
Deposit date:2001-04-12
Release date:2001-05-02
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Combinatorial computational method gives new picomolar ligands for a known enzyme.
Proc.Natl.Acad.Sci.USA, 99, 2002
7L99
DownloadVisualize
BU of 7l99 by Molmil
Crystal structure of BRDT bromodomain 2 in complex with CDD-1302
Descriptor: Bromodomain testis-specific protein, N-[3-(acetylamino)-4-methylphenyl]-3-(4-amino-2-methylphenyl)-1-methyl-1H-indazole-5-carboxamide, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500)
Authors:Sharma, R, Yu, Z, Ku, A.F, Anglin, J.L, Ucisik, M.N, Faver, J.C, Sankaran, B, Kim, C, Matzuk, M.M.
Deposit date:2021-01-03
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery and characterization of bromodomain 2-specific inhibitors of BRDT.
Proc.Natl.Acad.Sci.USA, 118, 2021
2K9J
DownloadVisualize
BU of 2k9j by Molmil
Integrin alphaIIb-beta3 transmembrane complex
Descriptor: Integrin alpha-IIb light chain, Integrin beta-3
Authors:Lau, T, Kim, C, Ginsberg, M.H, Ulmer, T.S.
Deposit date:2008-10-15
Release date:2009-03-24
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling
Embo J., 28, 2009
7UBO
DownloadVisualize
BU of 7ubo by Molmil
Crystal Structure of the first bromodomain of human BRDT in complex with the inhibitor CCD-956
Descriptor: Bromodomain testis-specific protein, DIMETHYL SULFOXIDE, N-[(2R)-1-(methylamino)-3-{1-[(4-methyl-2-oxo-1,2-dihydroquinolin-6-yl)acetyl]piperidin-4-yl}-1-oxopropan-2-yl]-5-phenylpyridine-2-carboxamide
Authors:Ta, H.M, Modukuri, R.K, Yu, Z, Tan, Z, Matzuk, M.M, Kim, C.
Deposit date:2022-03-15
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections.
Proc.Natl.Acad.Sci.USA, 119, 2022
4HPL
DownloadVisualize
BU of 4hpl by Molmil
PCGF1 Ub fold (RAWUL)/BCOR PUFD Complex
Descriptor: BCL-6 corepressor, Polycomb group RING finger protein 1
Authors:Junco, S.E, Wang, R, Gaipa, J, Taylor, A.B, Gearhart, M.D, Bardwell, V.J, Hart, P.J, Kim, C.A.
Deposit date:2012-10-24
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Polycomb Group Protein PCGF1 in Complex with BCOR Reveals Basis for Binding Selectivity of PCGF Homologs.
Structure, 21, 2013
2L8E
DownloadVisualize
BU of 2l8e by Molmil
Solution NMR structure of FCS domain of Human Polyhomeotic Homolog 1 (HPH1)
Descriptor: Polyhomeotic-like protein 1, ZINC ION
Authors:Ilangovan, U, Kim, C.
Deposit date:2011-01-11
Release date:2011-12-21
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:1H, 15N and 13C assigned chemical shifts of FCS domain from human polyhomeotic homolog 1
To be Published
4EZ1
DownloadVisualize
BU of 4ez1 by Molmil
Crystal structure of acetylcholine binding protein (AChBP) from Aplysia Californica in complex with alpha-conotoxin BuIA
Descriptor: Alpha-conotoxin BuIA, MANGANESE (II) ION, Soluble acetylcholine receptor
Authors:Talley, T.T, Reger, A.S, Kim, C, Sankaran, B, Ho, K, Taylor, P, McIntosh, J.M.
Deposit date:2012-05-02
Release date:2013-05-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Pairwise interaction of alpha-conotoxin BuIA Pro6 with the beta subunit of nicotinic acetylcholine receptor
To be Published
2HG4
DownloadVisualize
BU of 2hg4 by Molmil
Structure of the ketosynthase-acyltransferase didomain of module 5 from DEBS.
Descriptor: 6-Deoxyerythronolide B Synthase, ACETATE ION, CHLORIDE ION, ...
Authors:Tang, Y, Kim, C.Y, Mathews, I.I, Cane, D.E, Khosla, C.
Deposit date:2006-06-26
Release date:2006-07-11
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:The 2.7-A crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3IM4
DownloadVisualize
BU of 3im4 by Molmil
Crystal structure of cAMP-dependent Protein Kinase A Regulatory Subunit I alpha in complex with dual-specific A-Kinase Anchoring Protein 2
Descriptor: Dual specificity A kinase-anchoring protein 2, ZINC ION, cAMP-dependent protein kinase type I-alpha regulatory subunit
Authors:Sarma, G.N, Kinderman, F.S, Kim, C, von Daake, S, Taylor, S.S.
Deposit date:2009-08-09
Release date:2010-02-02
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.285 Å)
Cite:Structure of D-AKAP2:PKA RI Complex: Insights into AKAP Specificity and Selectivity
Structure, 18, 2010
4HPM
DownloadVisualize
BU of 4hpm by Molmil
PCGF1 Ub fold (RAWUL)/BCORL1 PUFD Complex
Descriptor: BCL-6 corepressor-like protein 1, PHOSPHATE ION, Polycomb group RING finger protein 1
Authors:Junco, S.E, Wang, R, Gaipa, J, Taylor, A.B, Gearhart, M.D, Bardwell, V.J, Hart, P.J, Kim, C.A.
Deposit date:2012-10-24
Release date:2013-05-01
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of the Polycomb Group Protein PCGF1 in Complex with BCOR Reveals Basis for Binding Selectivity of PCGF Homologs.
Structure, 21, 2013
3IM3
DownloadVisualize
BU of 3im3 by Molmil
Crystal structure of PKA RI alpha dimerization/docking domain
Descriptor: FORMIC ACID, cAMP-dependent protein kinase type I-alpha regulatory subunit
Authors:Sarma, G.N, Kinderman, F.S, Kim, C, von Daake, S, Taylor, S.S.
Deposit date:2009-08-09
Release date:2010-02-02
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of D-AKAP2:PKA RI Complex: Insights into AKAP Specificity and Selectivity
Structure, 18, 2010
3G9W
DownloadVisualize
BU of 3g9w by Molmil
Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Integrin beta-1D, ...
Authors:Anthis, N.J, Wegener, K.L, Ye, F, Kim, C, Lowe, E.D, Vakonakis, I, Bate, N, Critchley, D.R, Ginsberg, M.H, Campbell, I.D.
Deposit date:2009-02-15
Release date:2009-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.165 Å)
Cite:The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
Embo J., 28, 2009
6BDL
DownloadVisualize
BU of 6bdl by Molmil
Crystal structure of cGMP-dependent protein kinase Ialpha (PKG Ialpha) catalytic domain in apo state
Descriptor: IMIDAZOLE, cGMP-dependent protein kinase 1
Authors:Qin, L, Sankaran, B, Kim, C.
Deposit date:2017-10-23
Release date:2018-10-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structure of cGMP-dependent protein kinase Ialpha (PKG Ialpha) catalytic domain
to be published
3GS2
DownloadVisualize
BU of 3gs2 by Molmil
Ring1B C-terminal domain/Cbx7 Cbox Complex
Descriptor: Chromobox protein homolog 7, E3 ubiquitin-protein ligase RING2, SULFATE ION, ...
Authors:Wang, R, Taylor, A.B, Kim, C.A.
Deposit date:2009-03-26
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:Polycomb Group Targeting through Different Binding Partners of RING1B C-Terminal Domain.
Structure, 18, 2010
2HWN
DownloadVisualize
BU of 2hwn by Molmil
Crystal Structure of RII alpha Dimerization/Docking domain of PKA bound to the D-AKAP2 peptide
Descriptor: A Kinase binding peptide, GLYCEROL, cAMP-dependent protein kinase type II-alpha regulatory subunit
Authors:Kinderman, F, Kim, C.
Deposit date:2006-08-01
Release date:2006-11-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A Dynamic Mechanism for AKAP Binding to RII Isoforms of cAMP-Dependent Protein Kinase.
Mol.Cell, 24, 2006
2FGG
DownloadVisualize
BU of 2fgg by Molmil
Crystal Structure of Rv2632c
Descriptor: Hypothetical protein Rv2632c/MT2708
Authors:Yu, M, Bursey, E.H, Radhakannan, T, Segelke, B.W, Lekin, T, Toppani, D, Kim, C.Y, Kaviratne, T, Woodruff, T, Terwilliger, T.C, Hung, L.W, TB Structural Genomics Consortium (TBSGC)
Deposit date:2005-12-21
Release date:2006-02-14
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Rv2632c
To be Published
1W30
DownloadVisualize
BU of 1w30 by Molmil
PyrR of Mycobacterium Tuberculosis as a potential drug target
Descriptor: PYRR BIFUNCTIONAL PROTEIN
Authors:Kantardjieff, K.A, Vasquez, C, Castro, P, Warfel, N.N, Rho, B.-S, Lekin, T, Kim, C.-Y, Segelke, B.W, Terwilliger, T, Rupp, B, TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-07-11
Release date:2004-09-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Pyrr (Rv1379) from Mycobacterium Tuberculosis: A Persistence Gene and Protein Drug Target
Acta Crystallogr.,Sect.D, 61, 2005

227561

PDB entries from 2024-11-20

PDB statisticsPDBj update infoContact PDBjnumon