3RO5
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![BU of 3ro5 by Molmil](/molmil-images/mine/3ro5) | Crystal structure of influenza A virus nucleoprotein with ligand | Descriptor: | Nucleocapsid protein, [4-(2-chloro-4-nitrophenyl)piperazin-1-yl][3-(2-methoxyphenyl)-5-methyl-1,2-oxazol-4-yl]methanone | Authors: | Pearce, B.C, Edavettal, S, McDonnell, P.A, Lewis, H.A, Steinbacher, S, Baldwin, E.T, Langley, D.R, Maskos, K, Mortl, M, Kiefersauer, R. | Deposit date: | 2011-04-25 | Release date: | 2011-09-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers. Proc.Natl.Acad.Sci.USA, 108, 2011
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1Z5H
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![BU of 1z5h by Molmil](/molmil-images/mine/1z5h) | Crystal structures of the Tricorn interacting Factor F3 from Thermoplasma acidophilum | Descriptor: | SULFATE ION, Tricorn protease interacting factor F3, ZINC ION | Authors: | Kyrieleis, O.J.P, Goettig, P, Kiefersauer, R, Huber, R, Brandstetter, H. | Deposit date: | 2005-03-18 | Release date: | 2005-06-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structures of the Tricorn Interacting Factor F3 from Thermoplasma acidophilum, a Zinc Aminopeptidase in Three Different Conformations J.MOL.BIOL., 349, 2005
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1Z1W
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![BU of 1z1w by Molmil](/molmil-images/mine/1z1w) | Crystal structures of the tricorn interacting facor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations | Descriptor: | SULFATE ION, Tricorn protease interacting factor F3, ZINC ION | Authors: | Kyrieleis, O.J.P, Goettig, P, Kiefersauer, R, Huber, R, Brandstetter, H. | Deposit date: | 2005-03-07 | Release date: | 2005-05-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structures of the Tricorn Interacting Factor F3 from Thermoplasma acidophilum, a Zinc Aminopeptidase in Three Different Conformations J.MOL.BIOL., 394, 2005
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1N5W
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![BU of 1n5w by Molmil](/molmil-images/mine/1n5w) | Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Oxidized form | Descriptor: | CU(I)-S-MO(VI)(=O)OH CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... | Authors: | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | Deposit date: | 2002-11-07 | Release date: | 2002-12-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1N63
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![BU of 1n63 by Molmil](/molmil-images/mine/1n63) | Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Carbon monoxide reduced state | Descriptor: | CU(I)-S-MO(IV)(=O)OH CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... | Authors: | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | Deposit date: | 2002-11-08 | Release date: | 2002-12-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1N61
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![BU of 1n61 by Molmil](/molmil-images/mine/1n61) | Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Dithionite reduced state | Descriptor: | CU(I)-S-MO(IV)(=O)OH CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... | Authors: | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | Deposit date: | 2002-11-08 | Release date: | 2002-12-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1N62
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![BU of 1n62 by Molmil](/molmil-images/mine/1n62) | Crystal Structure of the Mo,Cu-CO Dehydrogenase (CODH), n-butylisocyanide-bound state | Descriptor: | CU(I)-S-MO(IV)(=O)O-NBIC CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... | Authors: | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | Deposit date: | 2002-11-08 | Release date: | 2002-12-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1N60
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![BU of 1n60 by Molmil](/molmil-images/mine/1n60) | Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Cyanide-inactivated Form | Descriptor: | Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, Carbon monoxide dehydrogenase small chain, ... | Authors: | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | Deposit date: | 2002-11-08 | Release date: | 2002-12-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1ORV
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![BU of 1orv by Molmil](/molmil-images/mine/1orv) | Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... | Authors: | Engel, M, Hoffmann, T, Wagner, L, Wermann, M, Heiser, U, Kiefersauer, R, Huber, R, Bode, W, Demuth, H.U, Brandstetter, H. | Deposit date: | 2003-03-16 | Release date: | 2003-05-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Crystal Structure of Dipeptidyl Peptidase IV (CD26) Reveals its Functional Regulation and Enzymatic Mechanism Proc.Natl.Acad.Sci.USA, 100, 2003
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1P8J
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![BU of 1p8j by Molmil](/molmil-images/mine/1p8j) | CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR, ... | Authors: | Henrich, S, Cameron, A, Bourenkov, G.P, Kiefersauer, R, Huber, R, Lindberg, I, Bode, W, Than, M.E. | Deposit date: | 2003-05-07 | Release date: | 2003-07-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Crystal Structure of the Proprotein Processing Proteinase Furin Explains its Stringent Specificity Nat.Struct.Biol., 10, 2003
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1ORW
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![BU of 1orw by Molmil](/molmil-images/mine/1orw) | Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26) in Complex with a Peptidomimetic Inhibitor | Descriptor: | (2S)-PYRROLIDIN-2-YLMETHYLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Engel, M, Hoffmann, T, Wagner, L, Wermann, M, Heiser, U, Kiefersauer, R, Huber, R, Bode, W, Demuth, H.U, Brandstetter, H. | Deposit date: | 2003-03-16 | Release date: | 2003-05-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | The Crystal Structure of Dipeptidyl Peptidase IV (CD26) Reveals its Functional Regulation and Enzymatic Mechanism Proc.Natl.Acad.Sci.USA, 100, 2003
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1SEZ
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![BU of 1sez by Molmil](/molmil-images/mine/1sez) | Crystal Structure of Protoporphyrinogen IX Oxidase | Descriptor: | 2-{2-[4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOXY]ETHOXY}ETHANOL, 4-BROMO-3-(5'-CARBOXY-4'-CHLORO-2'-FLUOROPHENYL)-1-METHYL-5-TRIFLUOROMETHYL-PYRAZOL, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Koch, M, Breithaupt, C, Kiefersauer, R, Freigang, J, Huber, R, Messerschmidt, A. | Deposit date: | 2004-02-19 | Release date: | 2004-04-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis. Embo J., 23, 2004
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3TG6
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![BU of 3tg6 by Molmil](/molmil-images/mine/3tg6) | Crystal Structure of Influenza A Virus nucleoprotein with Ligand | Descriptor: | Nucleocapsid protein, [4-(2-chloro-4-nitrophenyl)piperazin-1-yl][3-(2-chloropyridin-3-yl)-5-methyl-1,2-oxazol-4-yl]methanone | Authors: | Pearce, B.C, Lewis, H.A, McDonnell, P.A, Steinbacher, S, Kiefersauer, R, Mortl, M, Maskos, K, Edavettal, S, Baldwin, E.T, Langley, D.R. | Deposit date: | 2011-08-17 | Release date: | 2012-08-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Biophysical and Structural Characterization of a Novel Class of Influenza Virus Inhibitors To be Published
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4LI5
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![BU of 4li5 by Molmil](/molmil-images/mine/4li5) | EGFR-K IN COMPLEX WITH N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxy-phenyl] Prop-2-enamide | Descriptor: | Epidermal growth factor receptor, N-(3-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl)propanamide, SODIUM ION | Authors: | Debreczeni, J.E, Seiffert, G.B, Kiefersauer, R, Augustin, M, Nagel, S, Ward, R, Anderton, M, Ashton, S, Bethel, P, Box, M, Butterworth, S, Colclough, N, Chroley, C, Chuaqui, C, Cross, D, Eberlein, C, Finlay, R, Hill, G, Grist, M, Klinowska, T, Lane, C, Martin, S, Orme, J, Smith, P, Wang, F, Waring, M. | Deposit date: | 2013-07-02 | Release date: | 2013-08-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR). J.Med.Chem., 56, 2013
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4DYT
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![BU of 4dyt by Molmil](/molmil-images/mine/4dyt) | Crystal Structure of WSN/A Influenza Nucleoprotein with Three Mutations (E53D, Y289H, Y313V) | Descriptor: | Nucleocapsid protein | Authors: | Lewis, H.A, Baldwin, E.T, Steinbacher, S, Maskos, K, Mortl, M, Kiefersauer, R, Edavettal, S, McDonnell, P.A, Pearce, B.C, Langley, D.R. | Deposit date: | 2012-02-29 | Release date: | 2013-03-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | To be determined To be Published
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4DYN
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![BU of 4dyn by Molmil](/molmil-images/mine/4dyn) | Crystal Structure of WSN/A Influenza Nucleoprotein with BMS-885838 Ligand Bound | Descriptor: | N-[4-chloranyl-5-[4-[[3-(2-methoxyphenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]piperazin-1-yl]-2-nitro-phenyl]pyridine-2-carboxamide, Nucleocapsid protein | Authors: | Lewis, H.A, Baldwin, E.T, Steinbacher, S, Maskos, K, Mortl, M, Kiefersauer, R, Edavettal, S, McDonnell, P.A, Pearce, B.C, Langley, D.R. | Deposit date: | 2012-02-29 | Release date: | 2013-03-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | To be determined To be Published
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4DYB
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![BU of 4dyb by Molmil](/molmil-images/mine/4dyb) | Crystal Structure of WSN/A Influenza Nucleoprotein with BMS-883559 Ligand Bound | Descriptor: | N-[4-chloranyl-5-[4-[[3-(2-methoxyphenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]piperazin-1-yl]-2-nitro-phenyl]thiophene-2-carboxamide, Nucleocapsid protein | Authors: | Lewis, H.A, Baldwin, E.T, Steinbacher, S, Maskos, K, Mortl, M, Kiefersauer, R, Edavettal, S, McDonnell, P.A, Pearce, B.C, Langley, D.R. | Deposit date: | 2012-02-28 | Release date: | 2013-03-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | To be determined To be Published
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4DYA
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![BU of 4dya by Molmil](/molmil-images/mine/4dya) | Crystal Structure of WSN/A Influenza Nucleoprotein with BMS-885986 Ligand Bound | Descriptor: | N-[4-chloranyl-5-[4-[[3-(2-methoxyphenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]piperazin-1-yl]-2-nitro-phenyl]furan-2-carboxamide, Nucleocapsid protein | Authors: | Lewis, H.A, Baldwin, E.T, Steinbacher, S, Maskos, K, Mortl, M, Kiefersauer, R, Edavettal, S, McDonnell, P.A, Pearce, B.C, Langley, D.R. | Deposit date: | 2012-02-28 | Release date: | 2013-03-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | To be determined To be Published
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4DYP
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![BU of 4dyp by Molmil](/molmil-images/mine/4dyp) | Crystal Structure of WSN/A Influenza Nucleoprotein with BMS-831780 Ligand Bound | Descriptor: | Nucleocapsid protein, [4-(5-bromanyl-3-methyl-pyridin-2-yl)piperazin-1-yl]-[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]methanone | Authors: | Lewis, H.A, Baldwin, E.T, Steinbacher, S, Maskos, K, Mortl, M, Kiefersauer, R, Edavettal, S, McDonnell, P.A, Pearce, B.C, Langley, D.R. | Deposit date: | 2012-02-29 | Release date: | 2013-03-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | To be determined To be Published
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4DYS
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![BU of 4dys by Molmil](/molmil-images/mine/4dys) | Crystal Structure of Apo Swine Flu Influenza Nucleoprotein | Descriptor: | Nucleocapsid protein | Authors: | Lewis, H.A, Baldwin, E.T, Steinbacher, S, Maskos, K, Mortl, M, Kiefersauer, R, Edavettal, S, McDonnell, P.A, Pearce, B.C, Langley, D.R. | Deposit date: | 2012-02-29 | Release date: | 2013-03-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | To be determined To be Published
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