Crystal Structure of Protoporphyrinogen IX Oxidase

Summary for 1SEZ

DescriptorProtoporphyrinogen oxidase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, 4-BROMO-3-(5'-CARBOXY-4'-CHLORO-2'-FLUOROPHENYL)-1-METHYL-5-TRIFLUOROMETHYL-PYRAZOL, ... (5 entities in total)
Functional Keywordsfad-binding, para-hydroxy-benzoate-hydroxylase fold (phbh-fold), monotopic membrane-binding domain, oxidoreductase
Biological sourceNicotiana tabacum (common tobacco)
Cellular locationMitochondrion O24164
Total number of polymer chains2
Total molecular weight114767.22
Koch, M.,Breithaupt, C.,Kiefersauer, R.,Freigang, J.,Huber, R.,Messerschmidt, A. (deposition date: 2004-02-19, release date: 2004-04-13, Last modification date: 2011-07-13)
Primary citation
Koch, M.,Breithaupt, C.,Kiefersauer, R.,Freigang, J.,Huber, R.,Messerschmidt, A.
Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis.
Embo J., 23:1720-1728, 2004
PubMed: 15057273 (PDB entries with the same primary citation)
DOI: 10.1038/sj.emboj.7600189
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.274284.8%6.2%5.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution