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PDB: 32 件
3HE4
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BU of 3he4 by Molmil
Heterospecific coiled-coil pair SYNZIP5:SYNZIP6
分子名称: SYNZIP5, SYNZIP6
著者Reinke, A.W, Grant, R.A, Keating, A.E.
登録日2009-05-07
公開日2010-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献A synthetic coiled-coil interactome provides heterospecific modules for molecular engineering.
J.Am.Chem.Soc., 132, 2010
5UUM
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BU of 5uum by Molmil
Human Mcl-1 in complex with a Bfl-1-specific selected peptide
分子名称: Bfl-1 specific peptide FS2, Induced myeloid leukemia cell differentiation protein Mcl-1, SULFATE ION, ...
著者Jenson, J.M, Grant, R.A, Keating, A.E.
登録日2017-02-17
公開日2017-06-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.346 Å)
主引用文献Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1.
Elife, 6, 2017
5UUP
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BU of 5uup by Molmil
Human Bfl-1 covalently cross-linked to an electrophilic variant of a Bfl-1-specific selected peptide
分子名称: Bcl-2-related protein A1, Bfl-1-specific selected peptide, SULFATE ION
著者Jenson, J.M, Grant, R.A, Keating, A.E.
登録日2017-02-17
公開日2017-06-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.726 Å)
主引用文献Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1.
Elife, 6, 2017
5UUK
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BU of 5uuk by Molmil
Human Bfl-1 in complex with a Bfl-1-specific selected peptide
分子名称: Bcl-2-related protein A1, Bfl-1-specific selected peptide, SULFATE ION
著者Jenson, J.M, Grant, R.A, Keating, A.E.
登録日2017-02-17
公開日2017-06-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.199 Å)
主引用文献Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1.
Elife, 6, 2017
5UUL
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BU of 5uul by Molmil
Human Bfl-1 in complex with PUMA BH3
分子名称: Bcl-2-binding component 3, Bcl-2-related protein A1, SULFATE ION
著者Jenson, J.M, Grant, R.A, Keating, A.E.
登録日2017-02-17
公開日2017-06-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1.
Elife, 6, 2017
5W89
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BU of 5w89 by Molmil
Crystal structure of human Mcl-1 in complex with modified Bim BH3 peptide SAH-MS1-18
分子名称: Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION, modified Bim BH3 peptide SAH-MS1-18
著者Rezaei Araghi, R, Jenson, J.M, Grant, R.A, Keating, A.E.
登録日2017-06-21
公開日2018-01-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5W8F
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BU of 5w8f by Molmil
Crystal structure of human Mcl-1 in complex with modified Bim BH3 peptide SAH-MS1-14
分子名称: Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION, modified Bim BH3 peptide SAH-MS1-14
著者Rezaei Araghi, R, Jenson, J.M, Grant, R.A, Keating, A.E.
登録日2017-06-21
公開日2018-01-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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