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PDB: 34 件

4H1L
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TCR interaction with peptide mimics of nickel offers structural insights in nickel contact allergy
分子名称: Ani2.3 TCR A chain, Ani2.3 TCR B chain, HLA class II histocompatibility antigen, ...
著者Kappler, J.W, Yin, L, Dai, S, Marrack, P.
登録日2012-09-10
公開日2012-11-14
最終更新日2013-09-04
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy.
Proc.Natl.Acad.Sci.USA, 109, 2012
1I3R
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CRYSTAL STRUCTURE OF A MUTANT IEK CLASS II MHC MOLECULE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FUSION PROTEIN CONSISTING OF MHC E-BETA-K PRECURSOR, ...
著者Kappler, J.W, Wilson, N.
登録日2001-02-15
公開日2001-06-20
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mutations changing the kinetics of class II MHC peptide exchange.
Immunity, 14, 2001
4H26
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TCR interaction with peptide mimics of nickel offers structure insight to nickel contact allergy
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ...
著者Kappler, J.W, Yin, L, Dai, S, Marrack, P, Crawford, F.
登録日2012-09-12
公開日2013-10-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy.
Proc.Natl.Acad.Sci.USA, 109, 2012
4H25
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TCR interaction with peptide mimics of nickel offers structure insights to nickel contact allergy
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ...
著者Kappler, J.W, Yin, L, Dai, S, Marrack, P, Crawford, F.
登録日2012-09-12
公開日2013-10-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy.
Proc.Natl.Acad.Sci.USA, 109, 2012
6NRE
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Monomeric Lipocalin Can F 6
分子名称: Lipocalin-Can f 6 allergen
著者Clayton G, M, Kappler J, W, Chan, S.
登録日2019-01-23
公開日2019-09-25
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structural characteristics of lipocalin allergens: Crystal structure of the immunogenic dog allergen Can f 6.
Plos One, 14, 2019
5DMK
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Crystal Structure of IAg7 in complex with RLGL-WE14
分子名称: CITRATE ANION, H-2 class II histocompatibility antigen, A-D alpha chain, ...
著者Wang, Y, Jin, N, Dai, S, Kappler, J.W.
登録日2015-09-08
公開日2015-10-28
最終更新日2016-04-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes.
Proc.Natl.Acad.Sci.USA, 112, 2015
2PXJ
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BU of 2pxj by Molmil
The complex structure of JMJD2A and monomethylated H3K36 peptide
分子名称: FE (II) ION, JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, ...
著者Chen, Z, Zang, J, Kappler, J, Hong, X, Crawford, F, Zhang, G.
登録日2007-05-14
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of the recognition of a methylated histone tail by JMJD2A
Proc.Natl.Acad.Sci.Usa, 104, 2007
2G5B
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Crystal Structure of the anti-Bax monoclonal antibody 6A7 and a Bax peptide.
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6A7 Fab Heavy Chain, 6A7 Fab Light Chain, ...
著者Peyerl, F.W, Dai, S, Murphy, G.A, Marrack, P, Kappler, J.W.
登録日2006-02-22
公開日2006-07-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Elucidation of some Bax conformational changes through crystallization of an antibody-peptide complex.
Cell Death Differ., 14, 2007
3C5Z
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Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR B3K506
分子名称: 3K peptide, Linker, and H-2 class II histocompatibility antigen (A beta chain), ...
著者Dai, S, Kappler, J.
登録日2008-02-01
公開日2008-04-29
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules.
Immunity, 28, 2008
3RGV
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A single TCR bound to MHCI and MHC II reveals switchable TCR conformers
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ...
著者Dai, S, Huseby, E, Scott-Browne, J, Rubtsova, K, Pinilla, C, Crawford, F, Marrack, P, Yin, L, Kappler, J.W.
登録日2011-04-09
公開日2011-07-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR Conformers.
Immunity, 35, 2011
1KTD
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CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO PIGEON CYTOCHROME C PEPTIDE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein consisting of cytochrome C peptide, glycine rich linker, ...
著者Fremont, D.H, Dai, S, Chiang, H, Crawford, F, Marrack, P, Kappler, J.
登録日2002-01-15
公開日2002-05-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of cytochrome c presentation by IE(k).
J.Exp.Med., 195, 2002
1KT2
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CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO MOTH CYTOCHROME C PEPTIDE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein consisting of cytochrome C peptide, ...
著者Fremont, D.H, Dai, S, Chiang, H, Crawford, F, Marrack, P, Kappler, J.
登録日2002-01-15
公開日2002-05-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of cytochrome c presentation by IE(k).
J.Exp.Med., 195, 2002
1LNU
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CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IAb BOUND TO EALPHA3K PEPTIDE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 class II histocompatibility antigen, A beta chain, ...
著者Liu, X, Dai, S, Crawford, F, Fruge, R, Marrack, P, Kappler, J.
登録日2002-05-03
公開日2002-08-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Alternate interactions define the binding of peptides to the MHC molecule IA(b).
Proc.Natl.Acad.Sci.USA, 99, 2002
3C5J
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Crystal structure of HLA DR52c
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Elongation factor 1-alpha 2, HLA class II histocompatibility antigen, ...
著者Dai, S, Kappler, J.W.
登録日2008-01-31
公開日2008-08-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles.
Proc.Natl.Acad.Sci.USA, 105, 2008
1PQ0
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Crystal structure of mouse Bcl-xl
分子名称: Apoptosis regulator Bcl-X
著者Liu, X, Dai, S, Zhu, Y, Marrack, P, Kappler, J.W.
登録日2003-06-17
公開日2003-09-23
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of a Bcl-xl/Bim fragment complex: Implications for Bim function
Immunity, 19, 2003
1PQ1
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Crystal structure of Bcl-xl/Bim
分子名称: Apoptosis regulator Bcl-X, BCL2-like protein 11
著者Liu, X, Dai, S, Zhu, Y, Marrack, P, Kappler, J.W.
登録日2003-06-17
公開日2003-09-23
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The structure of a Bcl-xl/Bim fragment complex: Implications for Bim function
Immunity, 19, 2003
1K8I
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CRYSTAL STRUCTURE OF MOUSE H2-DM
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II H2-M alpha chain, MHC class II H2-M beta 2 chain
著者Fremont, D.H, Crawford, F, Marrack, P, Hendrickson, W, Kappler, J.
登録日2001-10-24
公開日2001-12-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of mouse H2-M.
Immunity, 9, 1998
4P5M
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Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity and Autoimmunity
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, Y, Dai, S, Kappler, J.
登録日2014-03-18
公開日2014-08-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Cell, 158, 2014
1IEB
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HISTOCOMPATIBILITY ANTIGEN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-EK, SULFATE ION
著者Fremont, D.H, Hendrickson, W.A, Marrack, P, Kappler, J.
登録日1996-04-05
公開日1997-06-05
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of an MHC class II molecule with covalently bound single peptides.
Science, 272, 1996
1IEA
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HISTOCOMPATIBILITY ANTIGEN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-EK
著者Fremont, D.H, Hendrickson, W.A, Marrack, P, Kappler, J.
登録日1996-04-05
公開日1997-06-05
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of an MHC class II molecule with covalently bound single peptides.
Science, 272, 1996
3KPS
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Crystal Structure of the LC13 TCR in complex with HLA B*4405 bound to EEYLQAFTY a self peptide from the ABCD3 protein
分子名称: Beta-2-microglobulin, EEYLQAFTY, self peptide from the ATP binding cassette protein ABCD3, ...
著者Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J.
登録日2009-11-16
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPR
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Crystal Structure of the LC13 TCR in complex with HLA B*4405 bound to EEYLKAWTF a mimotope
分子名称: Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ...
著者Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J.
登録日2009-11-16
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPQ
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Crystal Structure of HLA B*4405 in complex with EEYLKAWTF, a mimotope
分子名称: Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ...
著者Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J.
登録日2009-11-16
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3LD8
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Structure of JMJD6 and Fab Fragments
分子名称: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, FE (III) ION, GLYCEROL, ...
著者Hong, X, Zang, J, White, J, Kappler, J.W, Wang, C, Zhang, G.
登録日2010-01-12
公開日2010-08-04
最終更新日2012-06-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Interaction of JMJD6 with single-stranded RNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KPL
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Crystal Structure of HLA B*4402 in complex with EEYLQAFTY a self peptide from the ABCD3 protein
分子名称: Beta-2-microglobulin, EEYLQAFTY, self peptide from the ATP binding cassette protein ABCD3, ...
著者Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J.
登録日2009-11-16
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献T cell allorecognition via molecular mimicry.
Immunity, 31, 2009

 

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