3NRX
| Insights into anti-parallel microtubule crosslinking by PRC1, a conserved non-motor microtubule binding protein | 分子名称: | Protein regulator of cytokinesis 1 | 著者 | Kapoor, T.M, Subramanian, R, Wilson-Kubalek, E.M, Arthur, C.P, Bick, M.J, Campbell, E.A, Darst, S.A, Milligan, R.A. | 登録日 | 2010-06-30 | 公開日 | 2010-08-18 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein. Cell(Cambridge,Mass.), 142, 2010
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3NRY
| Insights into anti-parallel microtubule crosslinking by PRC1, a conserved microtubule binding protein | 分子名称: | Protein regulator of cytokinesis 1 | 著者 | Kapoor, T.M, Subramanian, R, Wilson-Kubalek, E.M, Arthur, C.P, Bick, M.J, Campbell, E.A, Darst, S.A, Milligan, R.A. | 登録日 | 2010-07-01 | 公開日 | 2010-08-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein. Cell(Cambridge,Mass.), 142, 2010
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8VRJ
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8VRK
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8VA2
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5KMG
| Near-atomic cryo-EM structure of PRC1 bound to the microtubule | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Kellogg, E.H, Howes, S, Ti, S.-C, Ramirez-Aportela, E, Kapoor, T.M, Chacon, P, Nogales, E. | 登録日 | 2016-06-27 | 公開日 | 2016-08-03 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Near-atomic cryo-EM structure of PRC1 bound to the microtubule. Proc.Natl.Acad.Sci.USA, 113, 2016
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6E7C
| 14-pf 3-start GMPCPP-human alpha1B/beta2B microtubules | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | 著者 | Ti, S.C, Alushin, G.M, Kapoor, T.M. | 登録日 | 2018-07-25 | 公開日 | 2018-10-10 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Human beta-Tubulin Isotypes Can Regulate Microtubule Protofilament Number and Stability. Dev. Cell, 47, 2018
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6E7B
| 13-pf 3-start GMPCPP-human alpha1B/beta3 microtubules | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | 著者 | Ti, S.C, Alushin, G.M, Kapoor, T.M. | 登録日 | 2018-07-25 | 公開日 | 2018-10-10 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Human beta-Tubulin Isotypes Can Regulate Microtubule Protofilament Number and Stability. Dev. Cell, 47, 2018
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4L6Y
| Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1) | 分子名称: | Protein regulator of cytokinesis 1 | 著者 | Subramanian, R, Ti, S, Tan, L, Darst, S.A, Kapoor, T.M. | 登録日 | 2013-06-13 | 公開日 | 2013-07-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.3015 Å) | 主引用文献 | Marking and Measuring Single Microtubules by PRC1 and Kinesin-4. Cell(Cambridge,Mass.), 154, 2013
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4L3I
| Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1) | 分子名称: | Protein regulator of cytokinesis 1 | 著者 | Subramanian, R, Ti, S, Tan, L, Darst, S.A, Kapoor, T.M. | 登録日 | 2013-06-06 | 公開日 | 2013-07-17 | 最終更新日 | 2013-08-07 | 実験手法 | X-RAY DIFFRACTION (3.6005 Å) | 主引用文献 | Marking and Measuring Single Microtubules by PRC1 and Kinesin-4. Cell(Cambridge,Mass.), 154, 2013
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1NLP
| STRUCTURE OF SIGNAL TRANSDUCTION PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | C-SRC, NL2 (MN8-MN1-PLPPLP) | 著者 | Feng, S, Kapoor, T.M, Shirai, F, Combs, A.P, Schreiber, S.L. | 登録日 | 1996-08-04 | 公開日 | 1997-01-27 | 最終更新日 | 2023-11-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular basis for the binding of SH3 ligands with non-peptide elements identified by combinatorial synthesis. Chem.Biol., 3, 1996
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1NLO
| STRUCTURE OF SIGNAL TRANSDUCTION PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | C-SRC, NL1 (MN7-MN2-MN1-PLPPLP) | 著者 | Feng, S, Kapoor, T.M, Shirai, F, Combs, A.P, Schreiber, S.L. | 登録日 | 1996-08-04 | 公開日 | 1997-01-27 | 最終更新日 | 2023-11-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular basis for the binding of SH3 ligands with non-peptide elements identified by combinatorial synthesis. Chem.Biol., 3, 1996
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8VT7
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8VRD
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5IJ9
| Cryo EM density of microtubule assembled from human TUBB3-D417H mutant | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ti, S.C, Pamula, M.C, Howes, S.C, Duellberg, C, Cade, N.I, Kleiner, R.E, Forth, S, Surrey, T, Nogales, E, Kapoor, T.M. | 登録日 | 2016-03-01 | 公開日 | 2016-04-20 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends. Dev.Cell, 37, 2016
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5IJ0
| Cryo EM density of microtubule assembled from human TUBB3 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ti, S.-C, Pamula, M.C, Howes, S.C, Duellberg, C, Nicholas, C.I, Kleiner, R.E, Forth, S, Surrey, T, Nogales, E, Kapoor, T.M. | 登録日 | 2016-03-01 | 公開日 | 2016-04-20 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends. Dev.Cell, 37, 2016
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6X0U
| Structure of MZT1/GCP3-NHD and MZT1/GCP6-NHD in the gamma-TuRC lumenal bridge | 分子名称: | Gamma-tubulin complex component 3, Gamma-tubulin complex component 6, Mitotic-spindle organizing protein 1 | 著者 | Wieczorek, M, Huang, T.-L, Urnavicius, L, Hsia, K.-C, Kapoor, T.M. | 登録日 | 2020-05-17 | 公開日 | 2020-07-22 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | MZT Proteins Form Multi-Faceted Structural Modules in the gamma-Tubulin Ring Complex. Cell Rep, 31, 2020
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6X0V
| Structure of MZT2/GCP-NHD and CDK5Rap2 at position 13 of the gamma-TuRC | 分子名称: | Centrosome protein Cep215, Gamma-tubulin complex component 2, Mitotic-spindle organizing protein 2A | 著者 | Wieczorek, M, Huang, T.-L, Urnavicius, L, Hsia, K.-C, Kapoor, T.M. | 登録日 | 2020-05-17 | 公開日 | 2020-07-22 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | MZT Proteins Form Multi-Faceted Structural Modules in the gamma-Tubulin Ring Complex. Cell Rep, 31, 2020
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6OR5
| Full-length S. pombe Mdn1 in the presence of AMPPNP (ring region) | 分子名称: | Midasin, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Chen, Z, Suzuki, H, Wang, A.C, DiMaio, F, Walz, T, Kapoor, T.M. | 登録日 | 2019-04-29 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis. Cell, 175, 2018
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6P11
| Structure of spastin AAA domain (T692A mutant) in complex with JNJ-7706621 inhibitor | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide, Drosophila melanogaster Spastin AAA domain, ... | 著者 | Pisa, R, Cupido, T, Kapoor, T.M. | 登録日 | 2019-05-17 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins. Cell Chem Biol, 26, 2019
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6P10
| Structure of spastin AAA domain (N527C mutant) in complex with JNJ-7706621 inhibitor | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide, Drosophila melanogaster Spastin AAA domain, ... | 著者 | Pisa, R, Cupido, T, Kapoor, T.M. | 登録日 | 2019-05-17 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins. Cell Chem Biol, 26, 2019
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6P12
| Structure of spastin AAA domain (wild-type) in complex with diaminotriazole-based inhibitor | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-{[5-amino-1-(2-fluoro-6-methoxybenzene-1-carbonyl)-1H-1,2,4-triazol-3-yl]amino}-N-methylbenzamide, Drosophila melanogaster Spastin AAA domain, ... | 著者 | Pisa, R, Cupido, T, Kapoor, T.M. | 登録日 | 2019-05-17 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.94131851 Å) | 主引用文献 | Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins. Cell Chem Biol, 26, 2019
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6P14
| Structure of spastin AAA domain (T692A mutant) in complex with a diaminotriazole-based inhibitor (crystal form B) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-{[5-amino-1-(2-fluoro-6-methoxybenzene-1-carbonyl)-1H-1,2,4-triazol-3-yl]amino}-N-methylbenzamide, ACETATE ION, ... | 著者 | Pisa, R, Cupido, T, Kapoor, T.M. | 登録日 | 2019-05-17 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.93001127 Å) | 主引用文献 | Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins. Cell Chem Biol, 26, 2019
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6P13
| Structure of spastin AAA domain (T692A mutant) in complex with a diaminotriazole-based inhibitor (crystal form A) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-{[5-amino-1-(2-fluoro-6-methoxybenzene-1-carbonyl)-1H-1,2,4-triazol-3-yl]amino}-N-methylbenzamide, SULFATE ION, ... | 著者 | Pisa, R, Cupido, T, Kapoor, T.M. | 登録日 | 2019-05-17 | 公開日 | 2019-08-07 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins. Cell Chem Biol, 26, 2019
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6V69
| Structures of GCP4 and GCP5 in the native human gamma-tubulin ring complex | 分子名称: | Gamma-tubulin complex component 4, Gamma-tubulin complex component 5 | 著者 | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | 登録日 | 2019-12-04 | 公開日 | 2020-01-01 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
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