5IJ9

Cryo EM density of microtubule assembled from human TUBB3-D417H mutant

Summary for 5IJ9

• Entry DOI: 10.2210/pdb5ij9/pdb
• Related: 5IJ0
• EMDB information: 8094 8095
• Descriptor: Tubulin alpha-1B chain, Tubulin beta-3 chain, GUANOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: human, microtubules, mutant tubulin, hydrolysis, structural protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 97488.70

Authors

Ti, S.C.,Pamula, M.C.,Howes, S.C.,Duellberg, C.,Cade, N.I.,Kleiner, R.E.,Forth, S.,Surrey, T.,Nogales, E.,Kapoor, T.M. (deposition date: 2016-03-01, release date: 2016-04-20, Last modification date: 2024-03-06)

• Primary citation: Ti, S.C.,Pamula, M.C.,Howes, S.C.,Duellberg, C.,Cade, N.I.,Kleiner, R.E.,Forth, S.,Surrey, T.,Nogales, E.,Kapoor, T.M.; Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends.; Dev.Cell, 37:72-84, 2016; PubMed: 27046833; DOI: 10.1016/j.devcel.2016.03.003

Experimental method

ELECTRON MICROSCOPY (3.7 Å)