5IJ9
Cryo EM density of microtubule assembled from human TUBB3-D417H mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tubulin alpha-1B chain | polymer | 437 | 48665.0 | 1 | UniProt (P68363) Pfam (PF00091) Pfam (PF03953) | Homo sapiens (Human) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B (B) | Tubulin beta-3 chain | polymer | 426 | 47833.0 | 1 | UniProt (Q13509) Pfam (PF00091) Pfam (PF03953) | Homo sapiens (Human) | Tubulin beta-4 chain,Tubulin beta-III |
| 3 | C (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 5 | E (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) |
Sequence modifications
B: 1 - 426 (UniProt: Q13509)
| PDB | External Database | Details |
|---|---|---|
| His 417 | Asp 417 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 96498.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 990.7 | |
| All* | Total formula weight | 97488.7 |
