5IJ9
Cryo EM density of microtubule assembled from human TUBB3-D417H mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tubulin alpha-1B chain | polymer | 437 | 48665.0 | 1 | UniProt (P68363) Pfam (PF00091) Pfam (PF03953) In PDB | Homo sapiens (Human) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B | Tubulin beta-3 chain | polymer | 426 | 47833.0 | 1 | UniProt (Q13509) Pfam (PF00091) Pfam (PF03953) In PDB | Homo sapiens (Human) | Tubulin beta-4 chain,Tubulin beta-III |
| 3 | A | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | B | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) |
Sequence modifications
B: 1 - 426 (UniProt: Q13509)
| PDB | External Database | Details |
|---|---|---|
| His 417 | Asp 417 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 96498.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 990.7 | |
| All* | Total formula weight | 97488.7 |
