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PDB: 440 results

7TCA
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Cryo-EM structure of SARS-CoV-2 Omicron spike in complex with antibody A19-46.1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody A19-46.1, ...
Authors:Zhou, T, Kwong, P.D.
Deposit date:2021-12-23
Release date:2022-03-30
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
7TCC
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Cryo-EM structure of SARS-CoV-2 Omicron spike in complex with antibodies A19-46.1 and B1-182.1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody A19-46.1, ...
Authors:Zhou, T, Kwong, P.D.
Deposit date:2021-12-23
Release date:2022-03-30
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
7TC9
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Locally refined region of SARS-CoV-2 spike in complex with antibody A19-46.1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody A19-46.1, Light chain of antibody A19-46.1, ...
Authors:Zhou, T, Kwong, P.D.
Deposit date:2021-12-23
Release date:2022-03-30
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (5.08 Å)
Cite:Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
7TCQ
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BU of 7tcq by Molmil
Crystal structure of SARS-CoV-2 neutralizing antibody WS6 in complex with spike S2 peptide
Descriptor: Anti-SARS-CoV-2 antibody WS6 Fab heavy chain, Anti-SARS-CoV-2 antibody WS6 Fab light chain, DI(HYDROXYETHYL)ETHER, ...
Authors:Zhou, T, Kwong, P.D.
Deposit date:2021-12-28
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability.
Structure, 30, 2022
7U0D
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Local refinement of cryo-EM structure of the interface of the Omicron RBD in complex with antibodies B-182.1 and A19-46.1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 antibody A19-46.1, Heavy chain of SARS-CoV-2 antibody B1-182.1, ...
Authors:Zhou, T, kwong, P.D.
Deposit date:2022-02-17
Release date:2022-03-30
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
7U9O
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SARS-CoV-2 spike trimer RBD in complex with Fab NE12
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NE12 Fab heavy chain, NE12 Fab light chain, ...
Authors:Tsybovsky, Y, Kwong, P.D, Farci, P.
Deposit date:2022-03-11
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants.
Cell Rep, 41, 2022
7U9P
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SARS-CoV-2 spike trimer RBD in complex with Fab NA8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NA8 Fab heavy chain, NA8 Fab light chain, ...
Authors:Tsybovsky, Y, Kwong, P.D, Farci, P.
Deposit date:2022-03-11
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants.
Cell Rep, 41, 2022
7TZ0
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Cryo-EM structure of SARS-CoV-2 spike in complex with FSR22, an anti-SARS-CoV-2 DARPin (Local refinement of FSR22 and RBD)
Descriptor: DARPin FSR22, Spike glycoprotein
Authors:Kwon, Y.D, Gorman, J, Kwong, P.D.
Deposit date:2022-02-15
Release date:2022-12-07
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (4.17 Å)
Cite:A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
7TYZ
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Cryo-EM structure of SARS-CoV-2 spike in complex with FSR22, an anti-SARS-CoV-2 DARPin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DARPin FSR22, ...
Authors:Kwon, Y.D, Gorman, J, Kwong, P.D.
Deposit date:2022-02-15
Release date:2022-12-07
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (3.51 Å)
Cite:A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
8DW2
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BU of 8dw2 by Molmil
Cryo-EM structure of SARS-CoV-2 RBD in complex with anti-SARS-CoV-2 DARPin,SR22, and two antibody Fabs, S309 and CR3022
Descriptor: Antibody CR3022 heavy chain, Antibody CR3022 light chain, Antibody S309 heavy chain, ...
Authors:Kwon, Y.D, Gorman, J, Kwong, P.D.
Deposit date:2022-07-30
Release date:2022-12-07
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (4.11 Å)
Cite:A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
8DW3
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BU of 8dw3 by Molmil
Cryo-EM structure of SARS-CoV-2 RBD in complex with anti-SARS-CoV-2 DARPin,SR16m, and two antibody Fabs, S309 and CR3022
Descriptor: Anti-SARS-CoV-2 DARPin SR16m, Antibody S309 light chain, Spike protein S1, ...
Authors:Kwon, Y.D, Gorman, J, Kwong, P.D.
Deposit date:2022-07-30
Release date:2022-12-07
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (4.26 Å)
Cite:A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
8EEU
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BU of 8eeu by Molmil
Venezuelan equine encephalitis virus-like particle in complex with Fab SKT05
Descriptor: Coat protein, Fab SKT05 heavy chain, Fab SKT05 light chain
Authors:Tsybovsky, Y, Pletnev, S, Verardi, R, Roederer, M, Kwong, P.D.
Deposit date:2022-09-07
Release date:2023-07-19
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
8EEV
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BU of 8eev by Molmil
Venezuelan equine encephalitis virus-like particle in complex with Fab SKT-20
Descriptor: Coat protein, Fab SKT20 heavy chain, Fab SKT20 light chain
Authors:Tsybovsky, Y, Pletnev, S, Verardi, R, Roederer, M, Kwong, P.D.
Deposit date:2022-09-07
Release date:2023-07-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
8F6X
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cryo-EM structure of a structurally designed Human metapneumovirus F protein in complex with antibody MPE8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MPE8 Single chain variable fragment, Structurally designed HMPV F protein HMPV_v3B_D12_DS454,Fibritin
Authors:Zhou, T, Kwong, P.D, Morano, N.C, Ou, L.
Deposit date:2022-11-17
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:cryo-EM structure of a structurally designed Human metapneumovirus F protein in complex with antibody MPE8
To Be Published
8F7T
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BU of 8f7t by Molmil
Glycan-Base ConC Env Trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env gp120, ...
Authors:Olia, A.S, Kwong, P.D.
Deposit date:2022-11-20
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Soluble prefusion-closed HIV-envelope trimers with glycan-covered bases.
Iscience, 26, 2023
8F7Z
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BU of 8f7z by Molmil
VRC34.01_mm28 bound to fusion peptide
Descriptor: HIV-1 Env Fusion Peptide, VRC34_m228 Light Chain, VRC34_mm28 Heavy Chain
Authors:Olia, A.S, Kwong, P.D.
Deposit date:2022-11-21
Release date:2023-11-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site.
Nat Commun, 14, 2023
8FA0
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Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with NBD-14208, an HIV-1 gp120 antagonist
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 gp120 core, ...
Authors:Kwon, Y.D, Kwong, P.D.
Deposit date:2022-11-25
Release date:2023-01-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Antiviral Activity and Crystal Structures of HIV-1 gp120 Antagonists.
Int J Mol Sci, 23, 2022
8F9Z
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Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with NBD-14204, an HIV-1 gp120 antagonist
Descriptor: (5M)-N-{(1S)-2-amino-1-[5-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl}-5-[5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrole-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Kwon, Y.D, Kwong, P.D.
Deposit date:2022-11-25
Release date:2023-01-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Antiviral Activity and Crystal Structures of HIV-1 gp120 Antagonists.
Int J Mol Sci, 23, 2022
8FBW
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BU of 8fbw by Molmil
Crystal structure of SIV-1 V2 antibody NCI05 in complex with a V2 peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Zhou, T, Kwong, P.D, Van Wazer, D.J.
Deposit date:2022-11-30
Release date:2023-01-18
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Effect of Passive Administration of Monoclonal Antibodies Recognizing Simian Immunodeficiency Virus (SIV) V2 in CH59-Like Coil/Helical or beta-Sheet Conformations on Time of SIV mac251 Acquisition.
J.Virol., 97, 2023
8FIS
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BU of 8fis by Molmil
Structure of Bispecific CAP256V2LS-J3 Fab in complex with BG505 DS-SOSIP.664
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2022-12-16
Release date:2023-02-01
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency.
Mabs, 15, 2023
8FR6
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BU of 8fr6 by Molmil
Antibody vFP53.02 in complex with HIV-1 envelope trimer BG505 DS-SOSIP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Wang, S, Kwong, P.D.
Deposit date:2023-01-06
Release date:2023-04-19
Last modified:2023-06-07
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
8FLW
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BU of 8flw by Molmil
Cryo-EM Structure of PGT145 DU303 Fab in complex with BG505 DS-SOSIP.664
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2022-12-22
Release date:2023-05-31
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design.
Cell Rep, 42, 2023
8FK5
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Cryo-EM Structure of PG9RSH DU011 Fab in complex with BG505 DS-SOSIP.664
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2022-12-20
Release date:2023-05-31
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design.
Cell Rep, 42, 2023
8FL1
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Cryo-EM Structure of PG9RSH DU025 Fab in complex with BG505 DS-SOSIP.664
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2022-12-21
Release date:2023-05-31
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design.
Cell Rep, 42, 2023
6MQC
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Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-c.01 in complex with FP (residue 512-519)
Descriptor: 0PV-C.01 antibody Fab heavy chain, 0PV-C.01 antibody Fab light chain, HIV fusion peptide residue 512-519
Authors:Xu, K, Wang, Y, Kwong, P.D.
Deposit date:2018-10-09
Release date:2019-07-31
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019

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PDB entries from 2024-07-31

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