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PDB: 107 件
6RPT
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BU of 6rpt by Molmil
Structure of tick complement inhibitor CirpT1 complexed with macroglobubulin domain 4 of human complement C5
分子名称: Complement C5, GLYCEROL, Putative 8.9 kDa family member
著者Reichhardt, M.P, Lea, S.M, Johnson, S.
登録日2019-05-14
公開日2020-01-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An inhibitor of complement C5 provides structural insights into activation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6SAN
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BU of 6san by Molmil
SALSA / DMBT1 / GP340 SRCR domain 8 soaked in calcium and magnesium
分子名称: CHLORIDE ION, Deleted in malignant brain tumors 1 protein, GLYCEROL, ...
著者Reichhardt, M.P, Johnson, S, Loimaranta, V, Lea, S.M.
登録日2019-07-17
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR fold.
Life Sci Alliance, 3, 2020
6SA5
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BU of 6sa5 by Molmil
SALSA / DMBT1 / GP340 SRCR domain 8
分子名称: Deleted in malignant brain tumors 1 protein, GLYCEROL, MAGNESIUM ION, ...
著者Reichhardt, M.P, Johnson, S, Loimaranta, V, Lea, S.M.
登録日2019-07-16
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR fold.
Life Sci Alliance, 3, 2020
6SA4
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BU of 6sa4 by Molmil
SALSA / DMBT1 / GP340 SRCR domain 1
分子名称: CHLORIDE ION, Deleted in malignant brain tumors 1 protein, GLYCEROL, ...
著者Reichhardt, M.P, Lea, S.M, Johnson, S.
登録日2019-07-16
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR fold.
Life Sci Alliance, 3, 2020
7ALW
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BU of 7alw by Molmil
Nonameric cytoplasmic domain of SctV from Yersinia enterocolitica
分子名称: Low calcium response protein
著者Kuhlen, L, Johnson, S.
登録日2020-10-07
公開日2021-06-02
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Nonameric structures of the cytoplasmic domain of FlhA and SctV in the context of the full-length protein.
Plos One, 16, 2021
7ALJ
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BU of 7alj by Molmil
Structure of Drosophila Notch EGF domains 11-13
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurogenic locus Notch protein, ...
著者Suckling, R, Johnson, S, Lea, S.M.
登録日2020-10-06
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling.
Embo Rep., 22, 2021
7ALK
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BU of 7alk by Molmil
Structure of Drosophila C2-DSL-EGF1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neurogenic locus protein delta, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Suckling, R, Johnson, S, Lea, S.M.
登録日2020-10-06
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling.
Embo Rep., 22, 2021
7ALT
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BU of 7alt by Molmil
Structure of Drosophila Serrate C2-DSL-EGF1-EGF2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Suckling, R, Johnson, S, Lea, S.M.
登録日2020-10-07
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling.
Embo Rep., 22, 2021
7B29
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BU of 7b29 by Molmil
Complement inhibitor CirpA4 from Rhipicephalus appendiculatus
分子名称: CADMIUM ION, CHLORIDE ION, CirpA4
著者Lea, S.M, Johnson, S, Braunger, K.
登録日2020-11-26
公開日2021-12-08
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
7B2A
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BU of 7b2a by Molmil
Complement inhibitor CirpA5 from Rhipicephalus appendiculatus
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CirpA5
著者Lea, S.M, Johnson, S, Braunger, K.
登録日2020-11-26
公開日2021-12-08
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
7B2D
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BU of 7b2d by Molmil
Complement inhibitor CirpA1 from Rhipicephalus pulchellus
分子名称: CirpA1, D-MALATE
著者Lea, S.M, Johnson, S, Braunger, K.
登録日2020-11-26
公開日2021-12-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
7B26
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BU of 7b26 by Molmil
CirpA1 in complex with pseudo-monomeric Properdin lacking TSR2-3
分子名称: CirpA1, Properdin, alpha-D-mannopyranose, ...
著者Lea, S.M, Johnson, S, Braunger, K.
登録日2020-11-26
公開日2021-12-08
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
7B28
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BU of 7b28 by Molmil
Complement inhibitor CirpA3 from Rhipicephalus pulchellus
分子名称: CirpA3, SULFATE ION
著者Lea, S.M, Johnson, S, Braunger, K.
登録日2020-11-26
公開日2021-12-08
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
4B4A
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BU of 4b4a by Molmil
Structure of the TatC core of the twin arginine protein translocation system
分子名称: Lauryl Maltose Neopentyl Glycol, SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATC
著者Rollauer, S.E, Tarry, M.J, Jaaskelainen, M, Graham, J.E, Jaeger, F, Krehenbrink, M, Roversi, P, McDowell, M.A, Stansfeld, P.J, Johnson, S, Liu, S.M, Lukey, M.J, Marcoux, J, Robinson, C.V, Sansom, M.S, Palmer, T, Hogbom, M, Berks, B.C, Lea, S.M.
登録日2012-07-30
公開日2012-12-05
最終更新日2012-12-19
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the Tatc Core of the Twin-Arginine Protein Transport System.
Nature, 49, 2012
4BOE
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BU of 4boe by Molmil
Japanin from Rhipicephalus appendiculatus bound to cholesterol: Tetragonal crystal form
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Roversi, P, Johnson, S, Preston, S, Austyn, J.M, Nuttall, P, Lea, S.M.
登録日2013-05-19
公開日2014-05-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structural basis of cholesterol binding by a novel clade of dendritic cell modulators from ticks.
Sci Rep, 7, 2017
4TT9
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BU of 4tt9 by Molmil
Structure of the C-terminal SpoA domain of Shigella flexneri Spa33
分子名称: 1,2-ETHANEDIOL, Surface presentation of antigens protein SpaO
著者McDowell, M.A, Johnson, S, Lea, S.M.
登録日2014-06-20
公開日2015-06-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Characterisation of Shigella Spa33 and Thermotoga FliM/N reveals a new model for C-ring assembly in T3SS.
Mol.Microbiol., 99, 2016
4BQU
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BU of 4bqu by Molmil
Japanin from Rhipicephalus appendiculatus bound to cholesterol: Orthorhombic crystal form
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Roversi, P, Johnson, S, Preston, S, Austyn, J.M, Nuttall, P, Lea, S.M.
登録日2013-06-02
公開日2014-06-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural basis of cholesterol binding by a novel clade of dendritic cell modulators from ticks.
Sci Rep, 7, 2017
5MWE
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BU of 5mwe by Molmil
Complex between the Leucine Zipper (LZ, residues 490-567) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn)
分子名称: 1,2-ETHANEDIOL, 3,3',3''-phosphanetriyltripropanoic acid, Centrosomin, ...
著者Feng, Z, Johnson, S, Raff, J.W, Lea, S.M.
登録日2017-01-18
公開日2017-06-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
5MW9
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BU of 5mw9 by Molmil
Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) - L535E mutant form
分子名称: Centrosomin, ZINC ION
著者Feng, Z, Johnson, S, Raff, J.W, Lea, S.M.
登録日2017-01-18
公開日2017-06-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
5MVW
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BU of 5mvw by Molmil
Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Centrosomin, ...
著者Feng, Z, Johnson, S, Raff, J.W, Lea, S.M.
登録日2017-01-17
公開日2017-06-28
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
5MW0
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BU of 5mw0 by Molmil
Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) - L535E mutant form
分子名称: Centrosomin, ZINC ION
著者Feng, Z, Johnson, S, Raff, J.W, Lea, S.M.
登録日2017-01-17
公開日2017-06-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
5HCC
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BU of 5hcc by Molmil
Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Dermacentor andersoni RaCI3.
分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jore, M.M, Johnson, S, Lea, S.M.
登録日2016-01-04
公開日2016-03-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural basis for therapeutic inhibition of complement C5.
Nat.Struct.Mol.Biol., 23, 2016
5HCD
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BU of 5hcd by Molmil
Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Rhipicephalus microplus RaCI2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, Complement C5, ...
著者Jore, M.M, Johnson, S, Lea, S.M.
登録日2016-01-04
公開日2016-03-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Structural basis for therapeutic inhibition of complement C5.
Nat.Struct.Mol.Biol., 23, 2016
5HCE
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BU of 5hce by Molmil
Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Rhipicephalus appendiculatus RaCI1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, Complement C5, ...
著者Jore, M.M, Johnson, S, Lea, S.M.
登録日2016-01-04
公開日2016-03-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Structural basis for therapeutic inhibition of complement C5.
Nat.Struct.Mol.Biol., 23, 2016
4BFE
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BU of 4bfe by Molmil
Structure of the extracellular portion of mouse CD200RLa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 4, CYSTEINE, ...
著者Hatherley, D, Lea, S.M, Johnson, S, Barclay, A.N.
登録日2013-03-18
公開日2013-05-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of Cd200/Cd200 Receptor Family and Implications for Topology, Regulation, and Evolution
Structure, 21, 2013

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