6IG2
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![BU of 6ig2 by Molmil](/molmil-images/mine/6ig2) | Structure of mitochondrial CDP-DAG synthase Tam41 complexed with CTP, delta 74, F240A | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, Phosphatidate cytidylyltransferase, mitochondrial | Authors: | Jiao, H.Z, Yin, Y, Liu, Z.F. | Deposit date: | 2018-09-23 | Release date: | 2019-07-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.882 Å) | Cite: | Structures of the Mitochondrial CDP-DAG Synthase Tam41 Suggest a Potential Lipid Substrate Pathway from Membrane to the Active Site. Structure, 27, 2019
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6IG4
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![BU of 6ig4 by Molmil](/molmil-images/mine/6ig4) | Structure of mitochondrial CDP-DAG synthase Tam41, delta 74 | Descriptor: | PLATINUM (II) ION, Phosphatidate cytidylyltransferase, mitochondrial, ... | Authors: | Jiao, H.Z, Yin, Y, Liu, Z.F. | Deposit date: | 2018-09-23 | Release date: | 2019-07-10 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.261 Å) | Cite: | Structures of the Mitochondrial CDP-DAG Synthase Tam41 Suggest a Potential Lipid Substrate Pathway from Membrane to the Active Site. Structure, 27, 2019
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6LV0
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![BU of 6lv0 by Molmil](/molmil-images/mine/6lv0) | |
8K2X
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![BU of 8k2x by Molmil](/molmil-images/mine/8k2x) | CXCR3-DNGi complex activated by CXCL10 | Descriptor: | C-X-C motif chemokine 10, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Jiao, H.Z, Hu, H.L. | Deposit date: | 2023-07-14 | Release date: | 2023-11-29 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487. Cell Discov, 9, 2023
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8K2W
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![BU of 8k2w by Molmil](/molmil-images/mine/8k2w) | Structure of CXCR3 complexed with antagonist AMG487 | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxidanylidene-pyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethyloxy)phenyl]ethanamide, ... | Authors: | Jiao, H.Z, Hu, H.L. | Deposit date: | 2023-07-14 | Release date: | 2023-11-29 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487. Cell Discov, 9, 2023
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8WBC
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![BU of 8wbc by Molmil](/molmil-images/mine/8wbc) | |
8WBE
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![BU of 8wbe by Molmil](/molmil-images/mine/8wbe) | |
8WBD
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![BU of 8wbd by Molmil](/molmil-images/mine/8wbd) | |
8WBG
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![BU of 8wbg by Molmil](/molmil-images/mine/8wbg) | |
8WBH
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![BU of 8wbh by Molmil](/molmil-images/mine/8wbh) | |
8WBF
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![BU of 8wbf by Molmil](/molmil-images/mine/8wbf) | |
8WBB
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![BU of 8wbb by Molmil](/molmil-images/mine/8wbb) | |
8HNK
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![BU of 8hnk by Molmil](/molmil-images/mine/8hnk) | CXCR3-DNGi complex activated by CXCL11 | Descriptor: | C-X-C motif chemokine 11, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Jiao, H.Z, Hu, H.L. | Deposit date: | 2022-12-08 | Release date: | 2023-11-29 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structural insights into the activation and inhibition of CXC chemokine receptor 3. Nat.Struct.Mol.Biol., 31, 2024
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8HNN
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![BU of 8hnn by Molmil](/molmil-images/mine/8hnn) | Structure of CXCR3 complexed with antagonist SCH546738 | Descriptor: | 3-azanyl-6-chloranyl-5-[(3S)-4-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-3-ethyl-piperazin-1-yl]pyrazine-2-carboxamide, CHOLESTEROL, Nb6, ... | Authors: | Jiao, H.Z, Hu, H.L. | Deposit date: | 2022-12-08 | Release date: | 2023-11-29 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural insights into the activation and inhibition of CXC chemokine receptor 3. Nat.Struct.Mol.Biol., 31, 2024
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8HNL
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![BU of 8hnl by Molmil](/molmil-images/mine/8hnl) | CXCR3-DNGi complex activated by PS372424 | Descriptor: | (3S)-N-[(2S)-5-carbamimidamido-1-(cyclohexylmethylamino)-1-oxidanylidene-pentan-2-yl]-2-(4-oxidanylidene-4-phenyl-butanoyl)-3,4-dihydro-1H-isoquinoline-3-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Jiao, H.Z, Hu, H.L. | Deposit date: | 2022-12-08 | Release date: | 2023-11-29 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Structural insights into the activation and inhibition of CXC chemokine receptor 3. Nat.Struct.Mol.Biol., 31, 2024
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8HNM
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![BU of 8hnm by Molmil](/molmil-images/mine/8hnm) | CXCR3-DNGi complex activated by VUF11222 | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Jiao, H.Z, Hu, H.L. | Deposit date: | 2022-12-08 | Release date: | 2023-11-29 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | Structural insights into the activation and inhibition of CXC chemokine receptor 3. Nat.Struct.Mol.Biol., 31, 2024
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6LVF
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![BU of 6lvf by Molmil](/molmil-images/mine/6lvf) | Cryo-EM structure of the multiple peptide resistance factor (MprF) loaded with one lysyl-phosphatidylglycerol molecule | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, Low pH-inducible protein LpiA, ... | Authors: | Song, D.F, Jiao, H.Z, Liu, Z.F. | Deposit date: | 2020-02-02 | Release date: | 2021-02-03 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Phospholipid translocation captured in a bifunctional membrane protein MprF. Nat Commun, 12, 2021
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7DUW
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![BU of 7duw by Molmil](/molmil-images/mine/7duw) | Cryo-EM structure of the multiple peptide resistance factor (MprF) loaded with two lysyl-phosphatidylglycerol molecules | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (2~{R},3~{S},4~{S},5~{S},6~{S})-2-(hydroxymethyl)-6-[(2~{R},3~{S},4~{R},5~{R},6~{R})-2-(hydroxymethyl)-6-[2-[[(2~{R},3~{S},4~{R},5~{R},6~{S})-6-(hydroxymethyl)-5-[(2~{S},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3,4-bis(oxidanyl)oxan-2-yl]oxymethyl]-4-[(1~{R},2~{R},4~{S},5'~{R},6~{R},7~{R},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxy-butoxy]-4,5-bis(oxidanyl)oxan-3-yl]oxy-oxane-3,4,5-triol, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... | Authors: | Song, D.F, Jiao, H.Z, Liu, Z.F. | Deposit date: | 2021-01-12 | Release date: | 2021-04-21 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Phospholipid translocation captured in a bifunctional membrane protein MprF. Nat Commun, 12, 2021
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