8HNM

CXCR3-DNGi complex activated by VUF11222

Summary for 8HNM

• Entry DOI: 10.2210/pdb8hnm/pdb
• EMDB information: 34916
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• Functional Keywords: g protein coupled receptor, chemokine receptor, cxcr3, vuf11222, complex, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 192213.73

Authors

Jiao, H.Z.,Hu, H.L. (deposition date: 2022-12-08, release date: 2023-11-29, Last modification date: 2024-01-17)

• Primary citation: Jiao, H.,Pang, B.,Liu, A.,Chen, Q.,Pan, Q.,Wang, X.,Xu, Y.,Chiang, Y.C.,Ren, R.,Hu, H.; Structural insights into the activation and inhibition of CXC chemokine receptor 3.; Nat.Struct.Mol.Biol., 2024; PubMed: 38177682; DOI: 10.1038/s41594-023-01175-5

Experimental method

ELECTRON MICROSCOPY (2.94 Å)