8K2X

CXCR3-DNGi complex activated by CXCL10

Summary for 8K2X

• Entry DOI: 10.2210/pdb8k2x/pdb
• EMDB information: 36842
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• Functional Keywords: g protein coupled receptor, chemokine receptor, cxcr3, cxcl10, complex, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 202299.74

Authors

Jiao, H.Z.,Hu, H.L. (deposition date: 2023-07-14, release date: 2023-11-29, Last modification date: 2025-07-16)

• Primary citation: Jiao, H.,Pang, B.,Chiang, Y.C.,Chen, Q.,Pan, Q.,Ren, R.,Hu, H.; Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487.; Cell Discov, 9:119-119, 2023; PubMed: 38012179; DOI: 10.1038/s41421-023-00617-0

Experimental method

ELECTRON MICROSCOPY (3.2 Å)