8K2W
Structure of CXCR3 complexed with antagonist AMG487
Summary for 8K2W
| Entry DOI | 10.2210/pdb8k2w/pdb |
| EMDB information | 36841 |
| Descriptor | Nb6, Soluble cytochrome b562,C-X-C chemokine receptor type 3,Kappa-type opioid receptor, CHOLESTEROL, ... (6 entities in total) |
| Functional Keywords | g protein coupled receptor, chemokine receptor, cxcr3, amg487, complex, signaling protein |
| Biological source | Lama glama More |
| Total number of polymer chains | 2 |
| Total formula weight | 77238.91 |
| Authors | Jiao, H.Z.,Hu, H.L. (deposition date: 2023-07-14, release date: 2023-11-29, Last modification date: 2025-07-23) |
| Primary citation | Jiao, H.,Pang, B.,Chiang, Y.C.,Chen, Q.,Pan, Q.,Ren, R.,Hu, H. Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487. Cell Discov, 9:119-119, 2023 Cited by PubMed: 38012179DOI: 10.1038/s41421-023-00617-0 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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