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PDB: 501 results

4ZWJ
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BU of 4zwj by Molmil
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
Descriptor: Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin
Authors:Kang, Y, Zhou, X.E, Gao, X, He, Y, Liu, W, Ishchenko, A, Barty, A, White, T.A, Yefanov, O, Han, G.W, Xu, Q, de Waal, P.W, Ke, J, Tan, M.H.E, Zhang, C, Moeller, A, West, G.M, Pascal, B, Eps, N.V, Caro, L.N, Vishnivetskiy, S.A, Lee, R.J, Suino-Powell, K.M, Gu, X, Pal, K, Ma, J, Zhi, X, Boutet, S, Williams, G.J, Messerschmidt, M, Gati, C, Zatsepin, N.A, Wang, D, James, D, Basu, S, Roy-Chowdhury, S, Conrad, C, Coe, J, Liu, H, Lisova, S, Kupitz, C, Grotjohann, I, Fromme, R, Jiang, Y, Tan, M, Yang, H, Li, J, Wang, M, Zheng, Z, Li, D, Howe, N, Zhao, Y, Standfuss, J, Diederichs, K, Dong, Y, Potter, C.S, Carragher, B, Caffrey, M, Jiang, H, Chapman, H.N, Spence, J.C.H, Fromme, P, Weierstall, U, Ernst, O.P, Katritch, V, Gurevich, V.V, Griffin, P.R, Hubbell, W.L, Stevens, R.C, Cherezov, V, Melcher, K, Xu, H.E, GPCR Network (GPCR)
Deposit date:2015-05-19
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.302 Å)
Cite:Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
Nature, 523, 2015
1FLZ
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BU of 1flz by Molmil
URACIL DNA GLYCOSYLASE WITH UAAP
Descriptor: URACIL, URACIL-DNA GLYCOSYLASE
Authors:Werner, R.M, Jiang, Y.L, Gordley, R.G, Jagadeesh, G.J, Ladner, J.E, Xiao, G, Tordova, M, Gilliland, G.L, Stivers, J.T.
Deposit date:2000-08-15
Release date:2001-01-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Stressing-out DNA? The contribution of serine-phosphodiester interactions in catalysis by uracil DNA glycosylase.
Biochemistry, 39, 2000
6LAE
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BU of 6lae by Molmil
Crystal structure of the DNA-binding domain of human XPA in complex with DNA
Descriptor: DNA (5'-D(P*GP*CP*AP*TP*CP*TP*CP*GP*CP*CP*T)-3'), DNA (5'-D(P*TP*GP*GP*CP*GP*AP*GP*AP*TP*GP*C)-3'), DNA repair protein complementing XP-A cells, ...
Authors:Lian, F.M, Yang, X, Jiang, Y.L, Yang, F, Li, C, Yang, W, Qian, C.
Deposit date:2019-11-12
Release date:2020-02-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:New structural insights into the recognition of undamaged splayed-arm DNA with a single pair of non-complementary nucleotides by human nucleotide excision repair protein XPA.
Int.J.Biol.Macromol., 148, 2020
8F7S
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BU of 8f7s by Molmil
Gi bound delta-opioid receptor in complex with deltorphin
Descriptor: CHOLESTEROL, Delta-type opioid receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E.
Deposit date:2022-11-20
Release date:2022-12-14
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures of the entire human opioid receptor family.
Cell, 186, 2023
8H8J
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BU of 8h8j by Molmil
Lodoxamide-bound GPR35 in complex with G13
Descriptor: 2,2'-[(2-chloro-5-cyano-1,3-phenylene)bis(azanediyl)]bis(oxoacetic acid), CALCIUM ION, CHOLESTEROL, ...
Authors:Yuan, Q, Duan, J, Liu, Q, Xu, H.E, Jiang, Y.
Deposit date:2022-10-23
Release date:2023-02-08
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Insights into divalent cation regulation and G 13 -coupling of orphan receptor GPR35.
Cell Discov, 8, 2022
6PWC
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BU of 6pwc by Molmil
A complex structure of arrestin-2 bound to neurotensin receptor 1
Descriptor: Beta-arrestin-1, Fab30 heavy chain, Fab30 light chain, ...
Authors:Yin, W, Li, Z, Jin, M, Yin, Y.-L, de Waal, P.W, Pal, K, Gao, X, He, Y, Gao, J, Wang, X, Zhang, Y, Zhou, H, Melcher, K, Jiang, Y, Cong, Y, Zhou, X.E, Yu, X, Xu, H.E.
Deposit date:2019-07-22
Release date:2019-12-04
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:A complex structure of arrestin-2 bound to a G protein-coupled receptor.
Cell Res., 29, 2019
8F7W
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BU of 8f7w by Molmil
Gi bound kappa-opioid receptor in complex with dynorphin
Descriptor: CHOLESTEROL, Dynorphin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E.
Deposit date:2022-11-20
Release date:2022-12-14
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structures of the entire human opioid receptor family.
Cell, 186, 2023
8F7R
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BU of 8f7r by Molmil
Gi bound mu-opioid receptor in complex with endomorphin
Descriptor: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E.
Deposit date:2022-11-20
Release date:2022-12-14
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structures of the entire human opioid receptor family.
Cell, 186, 2023
8F7Q
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BU of 8f7q by Molmil
Gi bound mu-opioid receptor in complex with beta-endorphin
Descriptor: Beta-endorphin, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E.
Deposit date:2022-11-20
Release date:2022-12-14
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Structures of the entire human opioid receptor family.
Cell, 186, 2023
8F7X
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BU of 8f7x by Molmil
Gi bound nociceptin receptor in complex with nociceptin peptide
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E.
Deposit date:2022-11-20
Release date:2022-12-14
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structures of the entire human opioid receptor family.
Cell, 186, 2023
5BOA
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BU of 5boa by Molmil
Crystal Structure of the Meningitis Pathogen Streptococcus suis adhesion Fhb bound to the disaccharide receptor Gb2
Descriptor: Translation initiation factor 2 (IF-2 GTPase), alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose
Authors:Zhang, C, Yu, Y, Yang, M, Jiang, Y.
Deposit date:2015-05-27
Release date:2016-05-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.708 Å)
Cite:Structural basis of the interaction between the meningitis pathogen Streptococcus suis adhesin Fhb and its human receptor.
Febs Lett., 590, 2016
8SGT
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BU of 8sgt by Molmil
Cryo-EM structure of human NCX1 in Ca2+ bound, activated state (group II in the presence of 0.5 mM Ca2+)
Descriptor: CALCIUM ION, Fab heavy chain, Fab light chain, ...
Authors:Xue, J, Jiang, Y.
Deposit date:2023-04-13
Release date:2023-10-11
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural mechanisms of the human cardiac sodium-calcium exchanger NCX1.
Nat Commun, 14, 2023
8SGJ
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BU of 8sgj by Molmil
Cryo-EM structure of human NCX1 in apo inactivated state
Descriptor: CALCIUM ION, Fab heavy chain, Fab light chain, ...
Authors:Xue, J, Jiang, Y.
Deposit date:2023-04-12
Release date:2023-10-11
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural mechanisms of the human cardiac sodium-calcium exchanger NCX1.
Nat Commun, 14, 2023
8SGI
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BU of 8sgi by Molmil
Cryo-EM structure of human NCX1 in complex with SEA0400
Descriptor: 2-{4-[(2,5-difluorophenyl)methoxy]phenoxy}-5-ethoxyaniline, CALCIUM ION, Fab heavy chain, ...
Authors:Xue, J, Jiang, Y.
Deposit date:2023-04-12
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural mechanisms of human cardiac sodium calcium exchanger NCX1
To Be Published
8FYF
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BU of 8fyf by Molmil
Human TMEM175-LAMP1 transmembrane domain only complex
Descriptor: Endosomal/lysosomal potassium channel TMEM175, Lysosome-associated membrane glycoprotein 1
Authors:Zhang, J.Y, Zeng, W.Z, Han, Y, Jiang, Y.X.
Deposit date:2023-01-26
Release date:2023-06-28
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel.
Mol.Cell, 83, 2023
8FY5
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BU of 8fy5 by Molmil
Human TMEM175-LAMP1 full-length complex
Descriptor: Endosomal/lysosomal potassium channel TMEM175, Lysosome-associated membrane glycoprotein 1
Authors:Zhang, J.Y, Zeng, W.Z, Han, Y, Jiang, Y.X.
Deposit date:2023-01-25
Release date:2023-06-28
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel.
Mol.Cell, 83, 2023
7RHI
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BU of 7rhi by Molmil
Cryo-EM structure of human rod CNGA1/B1 channel in cGMP-bound openII state
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-17
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
7RHJ
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BU of 7rhj by Molmil
Cryo-EM structure of human rod CNGA1/B1 channel in L-cis-Diltiazem-blocked open state
Descriptor: (2R,3R)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel beta-1, ...
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-17
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
7RHG
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BU of 7rhg by Molmil
Cryo-EM structure of human rod CNGA1/B1 channel in cAMP-bound state
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-17
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
7RHK
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BU of 7rhk by Molmil
Cryo-EM structure of human rod CNGA1/B1 channel in L-cis-Diltiazem-trapped closed state
Descriptor: (2R,3R)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel beta-1, ...
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-17
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
7RHH
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BU of 7rhh by Molmil
Cryo-EM structure of human rod CNGA1/B1 channel in cGMP-bound openI state
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-17
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
7RHL
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BU of 7rhl by Molmil
Cryo-EM structure of human rod Apo CNGA1/B1 channel with CLZ coiled coil
Descriptor: Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-17
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
8HDO
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BU of 8hdo by Molmil
Structure of A2BR bound to synthetic agonists BAY 60-6583
Descriptor: 2-[6-azanyl-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylethanamide, Adenosine A2b receptor, CHOLESTEROL, ...
Authors:Cai, H, Xu, Y, Xu, H.E, Jiang, Y.
Deposit date:2022-11-05
Release date:2023-01-18
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Structures of adenosine receptor A 2B R bound to endogenous and synthetic agonists.
Cell Discov, 8, 2022
8HDP
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BU of 8hdp by Molmil
Structure of A2BR bound to endogenous agonists adenosine
Descriptor: ADENOSINE, Adenosine A2b receptor, CHOLESTEROL, ...
Authors:Cai, H, Xu, Y, Xu, H.E, Jiang, Y.
Deposit date:2022-11-05
Release date:2023-01-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of adenosine receptor A 2B R bound to endogenous and synthetic agonists.
Cell Discov, 8, 2022
8HCX
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BU of 8hcx by Molmil
Cryo-EM structure of Endothelin1-bound ETBR-Gq complex
Descriptor: Endothelin receptor type B,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Endothelin-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Yuan, Q, Jiang, Y, Xu, H.E, Ji, Y, Duan, J.
Deposit date:2022-11-03
Release date:2023-03-22
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of peptide recognition and activation of endothelin receptors.
Nat Commun, 14, 2023

221051

数据于2024-06-12公开中

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