8K4F
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![BU of 8k4f by Molmil](/molmil-images/mine/8k4f) | DHODH in complex with compound A0 | 分子名称: | 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine, 6-[bis(oxidanyl)methyl]-5~{H}-pyrimidine-2,4-dione, ACETATE ION, ... | 著者 | Jian, L, Sun, Q. | 登録日 | 2023-07-18 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Discovery and Optimization of Novel h DHODH Inhibitors for the Treatment of Inflammatory Bowel Disease. J.Med.Chem., 66, 2023
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5D1F
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8IOF
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8ID1
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5GT1
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![BU of 5gt1 by Molmil](/molmil-images/mine/5gt1) | crystal structure of cbpa from L. salivarius REN | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Choline binding protein A, ... | 著者 | Jiang, L, Ren, F. | 登録日 | 2016-08-18 | 公開日 | 2017-07-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The Adhesion of Lactobacillus salivarius REN to a Human Intestinal Epithelial Cell Line Requires S-layer Proteins Sci Rep, 7, 2017
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1TOB
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![BU of 1tob by Molmil](/molmil-images/mine/1tob) | SACCHARIDE-RNA RECOGNITION IN AN AMINOGLYCOSIDE ANTIBIOTIC-RNA APTAMER COMPLEX, NMR, 7 STRUCTURES | 分子名称: | 1,3-DIAMINO-5,6-DIHYDROXYCYCLOHEXANE, 2,6-diammonio-2,3,6-trideoxy-alpha-D-glucopyranose, 3-ammonio-3-deoxy-alpha-D-glucopyranose, ... | 著者 | Jiang, L, Suri, A.K, Fiala, R, Patel, D.J. | 登録日 | 1996-12-12 | 公開日 | 1997-06-16 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Saccharide-RNA recognition in an aminoglycoside antibiotic-RNA aptamer complex. Chem.Biol., 4, 1997
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5Y2I
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3M61
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![BU of 3m61 by Molmil](/molmil-images/mine/3m61) | Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition | 分子名称: | Urokinase-type plasminogen activator, upain-1 W3A | 著者 | Jiang, L, Yuan, C, Wind, T, Andreasen, P.A, Chen, L, Meehan, E.J, Huang, M. | 登録日 | 2010-03-15 | 公開日 | 2010-04-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition TO BE PUBLISHED
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7VUE
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![BU of 7vue by Molmil](/molmil-images/mine/7vue) | Structural insight of the molecular mechanism of cilofexor bound to FXR | 分子名称: | 2-[3-[4-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-2-chloranyl-phenyl]-3-oxidanyl-azetidin-1-yl]pyridine-4-carboxylic acid, Bile acid receptor, Peptide from Nuclear receptor coactivator 2 | 著者 | Jiang, L, Chen, Y.C. | 登録日 | 2021-11-02 | 公開日 | 2022-03-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | 主引用文献 | Structural insight into the molecular mechanism of cilofexor binding to the farnesoid X receptor. Biochem.Biophys.Res.Commun., 595, 2022
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5XG4
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![BU of 5xg4 by Molmil](/molmil-images/mine/5xg4) | Crystal structure of uPA in complex with quercetin | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 3,5,7,3',4'-PENTAHYDROXYFLAVONE, Urokinase-type plasminogen activator | 著者 | Jiang, L, Huang, M. | 登録日 | 2017-04-11 | 公開日 | 2017-07-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A structural mechanism of flavonoids in inhibiting serine proteases Food Funct, 8, 2017
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1NEM
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![BU of 1nem by Molmil](/molmil-images/mine/1nem) | Saccharide-RNA recognition in the neomycin B / RNA aptamer complex | 分子名称: | 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranose, 2,6-diamino-2,6-dideoxy-beta-L-idopyranose-(1-3)-beta-D-ribofuranose, 2-DEOXY-D-STREPTAMINE, ... | 著者 | Jiang, L, Majumdar, A, Hu, W, Jaishree, T.J, Xu, W, Patel, D.J. | 登録日 | 1999-03-15 | 公開日 | 1999-08-31 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Saccharide-RNA recognition in a complex formed between neomycin B and an RNA aptamer Structure Fold.Des., 7, 1999
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4X1N
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![BU of 4x1n by Molmil](/molmil-images/mine/4x1n) | The crystal structure of mupain-1-16 in complex with murinised human uPA at pH7.4 | 分子名称: | Urokinase-type plasminogen activator, mupain-1-16, piperidine-1-carboximidamide | 著者 | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | 登録日 | 2014-11-25 | 公開日 | 2015-03-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility. Plos One, 9, 2014
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4X1Q
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![BU of 4x1q by Molmil](/molmil-images/mine/4x1q) | The crystal structure of mupain-1 in complex with murinised human uPA at pH7.4 | 分子名称: | Urokinase-type plasminogen activator, mupain-1 | 著者 | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | 登録日 | 2014-11-25 | 公開日 | 2015-03-25 | 最終更新日 | 2015-11-04 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility. Plos One, 9, 2014
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4X0W
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![BU of 4x0w by Molmil](/molmil-images/mine/4x0w) | The crystal structure of mupain-1-17 in complex with murinised human uPA | 分子名称: | SULFATE ION, Urokinase-type plasminogen activator, mupain-1-17, ... | 著者 | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | 登録日 | 2014-11-24 | 公開日 | 2015-10-21 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Distinctive binding modes and inhibitory mechanisms of two peptidic inhibitors of urokinase-type plasminogen activator with isomeric P1 residues. Int.J.Biochem.Cell Biol., 62, 2015
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4X1P
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![BU of 4x1p by Molmil](/molmil-images/mine/4x1p) | The crystal structure of mupain-1-17 in complex with murinised human uPA at pH4.6 | 分子名称: | MUPAIN-1-17, SULFATE ION, TRIETHYLENE GLYCOL, ... | 著者 | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | 登録日 | 2014-11-25 | 公開日 | 2015-10-21 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Distinctive binding modes and inhibitory mechanisms of two peptidic inhibitors of urokinase-type plasminogen activator with isomeric P1 residues. Int.J.Biochem.Cell Biol., 62, 2015
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4X1S
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![BU of 4x1s by Molmil](/molmil-images/mine/4x1s) | The crystal structure of mupain-1-16-D9A in complex with murinised human uPA at pH7.4 | 分子名称: | Urokinase-type plasminogen activator, mupain-1-16, piperidine-1-carboximidamide | 著者 | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | 登録日 | 2014-11-25 | 公開日 | 2015-10-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility. Plos One, 9, 2014
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4X1R
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![BU of 4x1r by Molmil](/molmil-images/mine/4x1r) | The crystal structure of mupain-1-12 in complex with murinised human uPA at pH7.4 | 分子名称: | 1-phenylguanidine, Urokinase-type plasminogen activator, mupain-1-12 | 著者 | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | 登録日 | 2014-11-25 | 公開日 | 2015-03-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility. Plos One, 9, 2014
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6L6L
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![BU of 6l6l by Molmil](/molmil-images/mine/6l6l) | Structural basis of NR4A2 homodimers binding to selective Nur-responsive elements | 分子名称: | DNA (5'-D(*AP*AP*AP*GP*GP*TP*CP*AP*AP*AP*CP*TP*GP*TP*GP*AP*CP*CP*TP*AP*T)-3'), DNA (5'-D(P*TP*AP*TP*AP*GP*GP*TP*CP*AP*CP*AP*GP*TP*TP*TP*GP*AP*CP*CP*TP*T)-3'), Nuclear receptor related 1, ... | 著者 | Jiang, L, Chen, Y. | 登録日 | 2019-10-29 | 公開日 | 2019-11-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.781 Å) | 主引用文献 | Structural basis of binding of homodimers of the nuclear receptor NR4A2 to selective Nur-responsive DNA elements. J.Biol.Chem., 294, 2019
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6L6Q
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4DVB
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![BU of 4dvb by Molmil](/molmil-images/mine/4dvb) | The crystal structure of the Fab fragment of pro-uPA antibody mAb-112 | 分子名称: | Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, TETRAETHYLENE GLYCOL | 著者 | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | 登録日 | 2012-02-23 | 公開日 | 2013-01-16 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Rezymogenation of active urokinase induced by an inhibitory antibody. Biochem.J., 449, 2013
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6LC1
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4ZKR
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4ZKS
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4IYP
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![BU of 4iyp by Molmil](/molmil-images/mine/4iyp) | structure of the nPP2Ac-alpha4 complex | 分子名称: | Immunoglobulin-binding protein 1, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | 著者 | Jiang, L, Stanevich, V, Satyshur, K.A, Xing, Y. | 登録日 | 2013-01-29 | 公開日 | 2013-04-17 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.797 Å) | 主引用文献 | Structural basis of protein phosphatase 2A stable latency. Nat Commun, 4, 2013
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4ZKN
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